salicylic acid has been researched along with Hyperpigmentation in 28 studies
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).
Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 9.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "Comparing the therapeutic efficacy of TCA 25% peels with those of salicylic acid 30% in patients with acne vulgaris." | 9.20 | Trichloroacetic Acid Versus Salicylic Acid in the Treatment of Acne Vulgaris in Dark-Skinned Patients. ( Abdel Meguid, AM; Elaziz Ahmed Attallah, DA; Omar, H, 2015) |
| "Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types." | 7.75 | Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. ( Garg, VK; Sarkar, R; Sinha, S, 2009) |
| " No adverse reaction was reported in either group." | 7.30 | Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial. ( He, X; Li, S; Niu, YG; Steel, A; Wang, HT; Zhang, XS; Zhang, Z, 2023) |
| " Treatment had no significant adverse effects." | 6.74 | Effectiveness, safety, and effect on quality of life of topical salicylic acid peels for treatment of postinflammatory hyperpigmentation in dark skin. ( Alam, M; Boone, SL; Helenowski, I; Joshi, SS; Kundu, RV; Rademaker, A; West, DP; White, L; Yoo, S, 2009) |
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 5.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "Comparing the therapeutic efficacy of TCA 25% peels with those of salicylic acid 30% in patients with acne vulgaris." | 5.20 | Trichloroacetic Acid Versus Salicylic Acid in the Treatment of Acne Vulgaris in Dark-Skinned Patients. ( Abdel Meguid, AM; Elaziz Ahmed Attallah, DA; Omar, H, 2015) |
| " Salicylic acid peel has effectiveness for both of acne and postinflammatory hyperpigmentation that are common in patients with skin of color." | 5.12 | Whitening effect of salicylic acid peels in Asian patients. ( Ahn, HH; Kim, IH, 2006) |
| "Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types." | 3.75 | Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. ( Garg, VK; Sarkar, R; Sinha, S, 2009) |
| "The results of this study suggest that superficial salicylic acid peels are both safe and efficacious for treatment of acne vulgaris, oily skin, textural changes, melasma, and post-inflammatory hyperpigmentation in patients with skin types V and VI." | 3.70 | The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. ( Grimes, PE, 1999) |
| " No adverse reaction was reported in either group." | 3.30 | Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial. ( He, X; Li, S; Niu, YG; Steel, A; Wang, HT; Zhang, XS; Zhang, Z, 2023) |
| " Treatment had no significant adverse effects." | 2.74 | Effectiveness, safety, and effect on quality of life of topical salicylic acid peels for treatment of postinflammatory hyperpigmentation in dark skin. ( Alam, M; Boone, SL; Helenowski, I; Joshi, SS; Kundu, RV; Rademaker, A; West, DP; White, L; Yoo, S, 2009) |
| "Hydroquinone 4% cream with 2% glycolic acid is safe and effective in improving photodamage on the neck and upper chest when used alone or in combination with salicylic acid peels." | 2.69 | Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest. ( Gladstone, HB; Jeffers, M; Moy, RL; Nguyen, SL; Ottomeyer, T; Williams, R; Wortzman, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.57) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 13 (46.43) | 24.3611 |
| 2020's | 5 (17.86) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, J | 1 |
| Jiang, R | 1 |
| Zhou, J | 1 |
| Xu, X | 1 |
| Sun, Z | 1 |
| Li, J | 1 |
| Chen, X | 1 |
| Li, Z | 1 |
| Yan, X | 1 |
| Zhao, D | 1 |
| Zheng, Z | 1 |
| Sun, L | 1 |
| Li, S | 1 |
| He, X | 1 |
| Zhang, Z | 1 |
| Zhang, XS | 1 |
| Niu, YG | 1 |
| Steel, A | 1 |
| Wang, HT | 1 |
| Tsukahara, R | 1 |
| Miyata, K | 1 |
| Go, U | 1 |
| Mitsuishi, T | 1 |
| How, KN | 1 |
| Lim, PY | 1 |
| Wan Ahmad Kammal, WSL | 1 |
| Shamsudin, N | 1 |
| Vakirlis, E | 1 |
| Theodosiou, G | 1 |
| Lallas, A | 1 |
| Apalla, Z | 1 |
| Sotiriou, E | 1 |
| Guarneri, C | 1 |
| Tchernev, G | 1 |
| Chokoeva, AA | 1 |
| Ananiev, J | 1 |
| Wollina, U | 1 |
| Abdel Meguid, AM | 1 |
| Elaziz Ahmed Attallah, DA | 1 |
| Omar, H | 1 |
| Shokeen, D | 1 |
| Mohamed Ali, BM | 1 |
| Gheida, SF | 1 |
| El Mahdy, NA | 1 |
| Sadek, SN | 1 |
| Garg, VK | 1 |
| Sinha, S | 1 |
| Sarkar, R | 1 |
| Joshi, SS | 1 |
| Boone, SL | 1 |
| Alam, M | 1 |
| Yoo, S | 1 |
| White, L | 1 |
| Rademaker, A | 1 |
| Helenowski, I | 1 |
| West, DP | 1 |
| Kundu, RV | 1 |
| Dahl, A | 1 |
| Yatskayer, M | 1 |
| Raab, S | 1 |
| Oresajo, C | 1 |
| Taibjee, SM | 1 |
| Cheung, ST | 1 |
| Laube, S | 1 |
| Lanigan, SW | 1 |
| Ahn, HH | 1 |
| Kim, IH | 1 |
| Hexsel, D | 1 |
| Arellano, I | 1 |
| Rendon, M | 1 |
| Grimes, PE | 1 |
| Gladstone, HB | 1 |
| Nguyen, SL | 1 |
| Williams, R | 1 |
| Ottomeyer, T | 1 |
| Wortzman, M | 1 |
| Jeffers, M | 1 |
| Moy, RL | 1 |
| Di Altobrando, A | 1 |
| Tabanelli, M | 1 |
| Crisanti, E | 1 |
| Dika, E | 1 |
| Patrizi, A | 1 |
| Savoia, F | 1 |
| Chan, C | 1 |
| Magro, CM | 1 |
| Pham, AK | 1 |
| LeBlanc, RE | 1 |
| Yan, S | 1 |
| Barton, DT | 1 |
| Pace, NC | 1 |
| Chapman, MS | 1 |
| Momtahen, S | 1 |
| Ward, PD | 1 |
| Miller, HL | 1 |
| Shipman, AR | 1 |
| Yeo, L | 1 |
| Husain, E | 1 |
| Rajpara, S | 1 |
| Oza, VS | 1 |
| Schulman, JM | 1 |
| Mully, TW | 1 |
| Ortiz, S | 1 |
| Regula, CG | 1 |
| Clarke, JT | 1 |
| Lin, MY | 1 |
| Chen, LJ | 1 |
| Ma, L | 1 |
| Wu, WY | 1 |
| Xiang, LH | 1 |
| Morris-Jones, R | 1 |
| Creamer, D | 1 |
| Selim, A | 1 |
| Roider, E | 1 |
| Schneider, J | 1 |
| Flaig, MJ | 1 |
| Ruzicka, T | 1 |
| Kunte, C | 1 |
| Berking, C | 1 |
| Castori, M | 1 |
| Scarciolla, O | 1 |
| Morlino, S | 1 |
| Manente, L | 1 |
| Biscaglia, A | 1 |
| Fragasso, A | 1 |
| Grammatico, P | 1 |
| Federici, S | 1 |
| Griffiths, D | 1 |
| Siberchicot, F | 1 |
| Chateil, JF | 1 |
| Gilbert, B | 1 |
| Lacombe, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing the Efficacy and Safety of Combined Glycolic Acid and Salicylic Acid Peel Versus Glycolic Acid Peel Alone in the Treatment of Melasma: A Split Face Study[NCT02812719] | Early Phase 1 | 0 participants (Actual) | Interventional | 2018-07-31 | Withdrawn (stopped due to Study did not receive funding and will not be implemented.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for salicylic acid and Hyperpigmentation
| Article | Year |
|---|---|
Postinflammatory hyperpigmentation in patients with skin of color.
Topics: Chemexfoliation; Dermatitis; Dermatologic Agents; Dicarboxylic Acids; Drug Combinations; Ethanol; Gl | 2016 |
Spontaneous Hair Repigmentation in an 80-Year-Old Man: A Case of Melanoma-Associated Hair Repigmentation and Review of the Literature.
Topics: Aged, 80 and over; Biopsy, Needle; Hair Color; Hair Follicle; Humans; Hyperpigmentation; Immunohisto | 2019 |
9 trials available for salicylic acid and Hyperpigmentation
| Article | Year |
|---|---|
Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial.
Topics: Acne Vulgaris; Adult; China; Humans; Hyperpigmentation; Salicylic Acid; Skin; Treatment Outcome | 2023 |
Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Facial Derma | 2020 |
Trichloroacetic Acid Versus Salicylic Acid in the Treatment of Acne Vulgaris in Dark-Skinned Patients.
Topics: Acne Vulgaris; Chemexfoliation; Dermatitis, Exfoliative; Double-Blind Method; Erythema; Female; Huma | 2015 |
Evaluation of salicylic acid peeling in comparison with topical tretinoin in the treatment of postinflammatory hyperpigmentation.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Chemexfoliation; Child; Combined Modality Therap | 2017 |
Effectiveness, safety, and effect on quality of life of topical salicylic acid peels for treatment of postinflammatory hyperpigmentation in dark skin.
Topics: Administration, Topical; Adult; Chemexfoliation; Female; Humans; Hyperpigmentation; Inflammation; Ke | 2009 |
Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone.
Topics: Adult; Aged; Chemistry, Pharmaceutical; Double-Blind Method; Ellagic Acid; Ethnicity; Face; Female; | 2013 |
Controlled study of excimer and pulsed dye lasers in the treatment of psoriasis.
Topics: Adult; Aged; Combined Modality Therapy; Female; Humans; Hyperpigmentation; Keratolytic Agents; Laser | 2005 |
Whitening effect of salicylic acid peels in Asian patients.
Topics: Acne Vulgaris; Adult; Asian People; Chemexfoliation; Colorimetry; Female; Humans; Hyperpigmentation; | 2006 |
Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest.
Topics: Chemexfoliation; Female; Glycolates; Humans; Hydroquinones; Hyperpigmentation; Keratolytic Agents; M | 2000 |
17 other studies available for salicylic acid and Hyperpigmentation
| Article | Year |
|---|---|
Salicylic acid in ginseng root alleviates skin hyperpigmentation disorders by inhibiting melanogenesis and melanosome transport.
Topics: alpha-MSH; Animals; Calcium; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Humans; Hy | 2021 |
Combined therapies of oral retinoid and topical salicylic acid in recalcitrant pigmented warts of a child.
Topics: Administration, Cutaneous; Administration, Oral; Alphapapillomavirus; Biopsy; Child; Drug Resistance | 2020 |
Terra firma-forme dermatosis: Differential diagnosis and response to salicylic acid therapy.
Topics: Administration, Topical; Child; Dermoscopy; Diagnosis, Differential; Exanthema; Female; Humans; Hype | 2019 |
[10-year-old boy with blackish brown skin alterations].
Topics: 2-Propanol; Child; Chronic Disease; Dermatitis; Diagnosis, Differential; Ethanol; Humans; Hyperpigme | 2014 |
Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study.
Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Cicatrix; Drug Combinations; Female; Glycolates; | 2009 |
Ethnic considerations in the treatment of Hispanic and Latin-American patients with hyperpigmentation.
Topics: Administration, Topical; Drug Therapy, Combination; Facial Dermatoses; Fluocinolone Acetonide; Gluco | 2006 |
The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups.
Topics: Acne Vulgaris; Adult; Black People; Chemexfoliation; Drug Administration Schedule; Female; Hispanic | 1999 |
Oral mucosal hyperpigmentation in a patient with a previous diagnosis of melanoma of the scalp.
Topics: Aged; Humans; Hyperpigmentation; Male; Melanoma; Mouth Mucosa; Scalp; Skin Neoplasms | 2020 |
A case of repigmentation and curling of hair on acitretin therapy.
Topics: Acitretin; Hair; Hair Color; Hair Diseases; Humans; Hyperpigmentation; Keratolytic Agents; Male; Mid | 2014 |
Poliosis circumscripta unmasking a scalp melanoma.
Topics: Adult; Hair Diseases; Head and Neck Neoplasms; Humans; Hyperpigmentation; Male; Melanoma; Scalp; Ski | 2015 |
A case of hair re-pigmentation from a scalp melanoma.
Topics: Biopsy, Needle; Diagnosis, Differential; Female; Hair; Hair Follicle; Humans; Hyperpigmentation; Imm | 2015 |
JAAD Grand Rounds quiz. Woman with hyperpigmented plaque and alopecia.
Topics: Adult; Alopecia; Diagnosis, Differential; Female; Forehead; Humans; Hyperpigmentation; Scalp; Sclero | 2009 |
Generalized reticulated hyperpigmentation induced by lichen planus.
Topics: Aged; Diagnosis, Differential; Female; Foot Dermatoses; Hand Dermatoses; Humans; Hyperpigmentation; | 2009 |
A clinically challenging pigmented lesion on the scalp.
Topics: Biopsy; Head and Neck Neoplasms; Humans; Hyperpigmentation; Male; Middle Aged; Neoplasms, Adnexal an | 2010 |
Hypopigmentation in the sites of regressed melanoma metastases after successful dacarbazine therapy.
Topics: Antineoplastic Agents, Alkylating; Dacarbazine; Forearm; Head and Neck Neoplasms; Humans; Hyperpigme | 2012 |
Whorled hairless nevus of the scalp, linear hyperpigmentation, and telangiectatic nevi of the lower limbs: a novel variant of the "phacomatosis complex".
Topics: Child; Hamartoma; Hemangioma; Humans; Hyperpigmentation; Lower Extremity Deformities, Congenital; Ma | 2012 |
Oculo-ectodermal syndrome: a new tumour predisposition syndrome.
Topics: Alopecia; Child, Preschool; Female; Follow-Up Studies; Genetic Predisposition to Disease; Granuloma, | 2004 |