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salicylic acid and Gastric Ulcer

salicylic acid has been researched along with Gastric Ulcer in 12 studies

Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).

Research Excerpts

ExcerptRelevanceReference
"Enprostil is a synthetic dehydro-prostaglandin E2 with gastroduodenal ulcer-healing and mucosal-protective properties."2.67Effect of enprostil on the gastroduodenal mucosa of healthy volunteers. ( Basuk, PM; Isenberg, JI; Karlin, DA; Lanza, FL; Robinson, MG, 1990)
" To assess the significance of this multiple probe approach, drug concentrations in each probe location were monitored after selected compounds were dosed to the ligated stomach by oral gavage."1.35The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach. ( Lunte, CE; Woo, KL, 2008)
"We compared the gastric toxic effect of aspirin (ASA) in both normal and diabetic rats, with that of NCX-4016, a derivative of ASA with nitric oxide (NO) releasing moiety."1.31Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats. ( Fujita, A; Takeuchi, K; Tashima, K; Umeda, M, 2000)
"Salicylic acid has been shown to decrease gastric mucosal lesions induced by indomethacin in the rat."1.27Salicylic acid blocks indomethacin-induced cyclooxygenase inhibition and lesion formation in rat gastric mucosa. ( Elashoff, J; Guth, PH; Hansen, D; Kauffman, GL; Ligumsky, M; Paulsen, G, 1985)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woo, KL1
Lunte, CE1
PAULS, F1
WICK, AN1
MACKAY, EM1
Morris, GP1
Wallace, JL1
Harding, PL1
Krausse, EJ1
Lolle, SJ1
Pagella, PG1
Bellavite, O1
Agozzino, S1
Donà, GC1
Cremonesi, P1
De Santis, F1
Weissenborn, U1
Maedge, S1
Sewing, KF1
Robert, A1
Tashima, K1
Fujita, A1
Umeda, M1
Takeuchi, K1
Lanza, FL1
Robinson, MG1
Isenberg, JI1
Basuk, PM1
Karlin, DA1
Ligumsky, M2
Sestieri, M1
Karmeli, F1
Rachmilewitz, D1
Thisted, B1
Krantz, T1
Strøom, J1
Sørensen, MB1
Guth, PH1
Elashoff, J1
Kauffman, GL1
Hansen, D2
Paulsen, G1
Whittle, BJ1
Salmon, JA1

Trials

1 trial available for salicylic acid and Gastric Ulcer

ArticleYear
Effect of enprostil on the gastroduodenal mucosa of healthy volunteers.
    Alimentary pharmacology & therapeutics, 1990, Volume: 4, Issue:6

    Topics: Double-Blind Method; Duodenum; Enprostil; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Human

1990

Other Studies

11 other studies available for salicylic acid and Gastric Ulcer

ArticleYear
The direct comparison of health and ulcerated stomach tissue: a multiple probe microdialysis sampling approach.
    Journal of pharmaceutical and biomedical analysis, 2008, Sep-10, Volume: 48, Issue:1

    Topics: Acetic Acid; Animals; Area Under Curve; Caffeine; Calibration; Chromatography, High Pressure Liquid;

2008
Inhibition of gastric ulceration in the rat by o-hydroxybenzoic (salicylic) acid.
    Science (New York, N.Y.), 1948, Jan-02, Volume: 106, Issue:2766

    Topics: Animals; Peptic Ulcer; Rats; Salicylic Acid; Stomach Ulcer

1948
Correlations between changes in indicators of gastric mucosal barrier integrity at time of exposure to "barrier breakers" and extent of hemorrhagic erosions one hour later.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:1

    Topics: Animals; Aspirin; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Mannitol; Prognosis;

1984
Pharmacological studies of imidazole 2-hydroxybenzoate (ITF 182), an antiinflammatory compound with an action on thromboxane A2 production.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System;

1983
Effect of oral 16,16-dimethyl prostaglandin E2 on gastric mucosal salicylate concentration in the rat.
    Pharmacology, 1984, Volume: 28, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Chromatography, High Pressure Liquid; Female; Gastric Mucosa

1984
Gastric cytoprotection by sodium salicylate.
    Prostaglandins, 1981, Volume: 21 Suppl

    Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; Male; Rats; Salicylates; Salicylic Acid; St

1981
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
    Life sciences, 2000, Aug-18, Volume: 67, Issue:13

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa;

2000
Protection by mild irritants against indomethacin-induced gastric mucosal damage in the rat: role of prostaglandin synthesis.
    Israel journal of medical sciences, 1986, Volume: 22, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Animals; Dinoprostone; Ethanol; Gastric Acid; Gastric M

1986
Acute salicylate self-poisoning in 177 consecutive patients treated in ICU.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Brain Edema; Cerebral Hemorrhage; Child;

1987
Salicylic acid blocks indomethacin-induced cyclooxygenase inhibition and lesion formation in rat gastric mucosa.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 178, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Indomethacin;

1985
Gastric ulcer formation and cyclo-oxygenase inhibition in cat antrum follows parenteral administration of aspirin but not salicylate.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: Animals; Aspirin; Cats; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Histamine; In

1985