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salicylic acid and Colorectal Neoplasms

salicylic acid has been researched along with Colorectal Neoplasms in 16 studies

Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"Salicylic acid (SA) has observationally been shown to decrease colorectal cancer (CRC) risk."8.02Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study. ( Albanes, D; Alwers, E; Amitay, E; Baron, JA; Bermejo, JL; Berndt, SI; Bishop, DT; Brenner, H; Buchanan, DD; Butterworth, A; Campbell, PT; Casey, G; CastellvĂ­-Bel, S; Chan, AT; Chang-Claude, J; Drew, DA; Figueiredo, JC; Gallinger, S; Giles, GG; Gruber, SB; Gsur, A; Gunter, MJ; Hampel, H; Harrison, TA; Hoffmeister, M; Hopper, JL; Keku, TO; Kim, HR; Kweon, SS; Li, CI; Li, L; Lin, Y; Lindblom, A; Lindor, NM; Marchand, LL; Moreno, V; Newcomb, PA; Nounu, A; Peters, U; Pharoah, PDP; Platz, EA; Relton, CL; Rennert, G; Richmond, RC; Sakoda, LC; Schafmayer, C; Scherer, D; Schoen, RE; Slattery, ML; Stadler, ZK; Stewart, ID; Surendran, P; Ulrich, CM; van Dujinhoven, FJB; Van Guelpen, B; Vodicka, P; Vodickova, L; Wareham, NJ; Weinstein, SJ; White, E; Williams, AC; Wolk, A; Woods, MO; Wu, AH; Zheng, W, 2021)
"Aspirin's potential as a drug continues to be evaluated for the prevention of colorectal cancer (CRC)."7.85Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer. ( Bhat, GJ; Callegari, E; Dachineni, R; Kesharwani, SS; Kumar, DR; Sankaranarayanan, R; Seefeldt, T; Tummala, H, 2017)
"Aspirin was introduced into clinical practice more than 100 years ago."6.41Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer. ( Lawrence, JR; Paterson, JR, 2001)
"Aspirin has recently been attracting attention as a cancer preventive drug, and its inhibitory effects on the development of various cancers have been reported in several large prospective studies."5.72Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells. ( Aono, Y; Horinaka, M; Iizumi, Y; Imai, A; Ishikawa, H; Mutoh, M; Nishimoto, E; Ono, H; Sakai, T; Takakura, H; Taniguchi, K; Yasuda, S, 2022)
"Intake of acetylsalicylic acid reduces the risk of cardiovascular disease and is associated with a decreased risk for colorectal cancer."5.08Urinary salicylate excretion in subjects eating a variety of diets shows that amounts of bioavailable salicylates in foods are low. ( Hollman, PC; Janssen, PL; Katan, MB; Reichman, E; van Staveren, WA; Venema, DP, 1996)
"A variety of studies have supported the finding that regular intake of aspirin (acetylsalicylic acid) or nonsteroidal anti-inflammatory agents can affect colorectal cancer carcinogenesis."5.08Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose. ( Boland, CR; Brenner, DE; Crowell, J; Kelloff, G; Krishnan, K; Normolle, D; Peters-Golden, M; Rock, CL; Ruffin, MT; Vaerten, MA, 1997)
"Salicylic acid (SA) has observationally been shown to decrease colorectal cancer (CRC) risk."4.02Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study. ( Albanes, D; Alwers, E; Amitay, E; Baron, JA; Bermejo, JL; Berndt, SI; Bishop, DT; Brenner, H; Buchanan, DD; Butterworth, A; Campbell, PT; Casey, G; CastellvĂ­-Bel, S; Chan, AT; Chang-Claude, J; Drew, DA; Figueiredo, JC; Gallinger, S; Giles, GG; Gruber, SB; Gsur, A; Gunter, MJ; Hampel, H; Harrison, TA; Hoffmeister, M; Hopper, JL; Keku, TO; Kim, HR; Kweon, SS; Li, CI; Li, L; Lin, Y; Lindblom, A; Lindor, NM; Marchand, LL; Moreno, V; Newcomb, PA; Nounu, A; Peters, U; Pharoah, PDP; Platz, EA; Relton, CL; Rennert, G; Richmond, RC; Sakoda, LC; Schafmayer, C; Scherer, D; Schoen, RE; Slattery, ML; Stadler, ZK; Stewart, ID; Surendran, P; Ulrich, CM; van Dujinhoven, FJB; Van Guelpen, B; Vodicka, P; Vodickova, L; Wareham, NJ; Weinstein, SJ; White, E; Williams, AC; Wolk, A; Woods, MO; Wu, AH; Zheng, W, 2021)
"Aspirin's potential as a drug continues to be evaluated for the prevention of colorectal cancer (CRC)."3.85Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer. ( Bhat, GJ; Callegari, E; Dachineni, R; Kesharwani, SS; Kumar, DR; Sankaranarayanan, R; Seefeldt, T; Tummala, H, 2017)
"Aspirin was introduced into clinical practice more than 100 years ago."2.41Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer. ( Lawrence, JR; Paterson, JR, 2001)
"Aspirin has recently been attracting attention as a cancer preventive drug, and its inhibitory effects on the development of various cancers have been reported in several large prospective studies."1.72Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells. ( Aono, Y; Horinaka, M; Iizumi, Y; Imai, A; Ishikawa, H; Mutoh, M; Nishimoto, E; Ono, H; Sakai, T; Takakura, H; Taniguchi, K; Yasuda, S, 2022)
"Evidence for cancer prophylaxis is based on ASA doses of at least 75mg/day."1.43Aspirin for cancer is no mere antiplatelet prototype. There is potential in its ancient roots. ( Baxter, GJ; Lawrence, JR; Paterson, JR, 2016)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (37.50)18.2507
2000's2 (12.50)29.6817
2010's6 (37.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Nounu, A1
Richmond, RC1
Stewart, ID1
Surendran, P1
Wareham, NJ1
Butterworth, A1
Weinstein, SJ1
Albanes, D1
Baron, JA2
Hopper, JL1
Figueiredo, JC1
Newcomb, PA1
Lindor, NM1
Casey, G1
Platz, EA1
Marchand, LL1
Ulrich, CM1
Li, CI1
van Dujinhoven, FJB1
Gsur, A1
Campbell, PT1
Moreno, V1
Vodicka, P1
Vodickova, L1
Amitay, E1
Alwers, E1
Chang-Claude, J1
Sakoda, LC1
Slattery, ML1
Schoen, RE1
Gunter, MJ1
CastellvĂ­-Bel, S1
Kim, HR1
Kweon, SS1
Chan, AT1
Li, L1
Zheng, W1
Bishop, DT1
Buchanan, DD1
Giles, GG1
Gruber, SB1
Rennert, G1
Stadler, ZK1
Harrison, TA1
Lin, Y1
Keku, TO1
Woods, MO1
Schafmayer, C1
Van Guelpen, B1
Gallinger, S1
Hampel, H1
Berndt, SI1
Pharoah, PDP1
Lindblom, A1
Wolk, A1
Wu, AH1
White, E1
Peters, U1
Drew, DA1
Scherer, D1
Bermejo, JL1
Brenner, H1
Hoffmeister, M1
Williams, AC1
Relton, CL1
Imai, A1
Horinaka, M1
Aono, Y1
Iizumi, Y1
Takakura, H1
Ono, H1
Yasuda, S1
Taniguchi, K1
Nishimoto, E1
Ishikawa, H1
Mutoh, M1
Sakai, T1
Dachineni, R1
Kumar, DR1
Callegari, E1
Kesharwani, SS1
Sankaranarayanan, R1
Seefeldt, T1
Tummala, H1
Bhat, GJ1
Lawrence, JR2
Baxter, GJ1
Paterson, JR2
Shaukat, A1
Grau, MV1
Church, TR1
Baxter, G1
Barry, EL1
Summers, R1
Sandler, RS1
Owen, RW1
Wimonwatwatee, T1
Spiegelhalder, B1
Bartsch, H1
Janssen, PL1
Hollman, PC1
Reichman, E1
Venema, DP1
van Staveren, WA1
Katan, MB1
Ruffin, MT1
Krishnan, K1
Rock, CL1
Normolle, D1
Vaerten, MA1
Peters-Golden, M1
Crowell, J1
Kelloff, G1
Boland, CR1
Brenner, DE1
Giardina, C1
Boulares, H1
Inan, MS1
Scheier, L1
Shah, SR1
Applebaum, DS1
Potenziani, S1
Huttenbach, YT1
Wolf, J1
Orengo, IF1
Rogers, JE1
Ohinata, A1
Dasari, A1
Eng, C1
Ha, JY1
Oh, EH1
Jung, MK1
Park, SE1
Kim, JT1
Hwang, IG1
Lee, M1
Duke, EE1
Munoz, J1
Holaday, L1
Sgouros, S1
Walsh, AR1

Reviews

2 reviews available for salicylic acid and Colorectal Neoplasms

ArticleYear
Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer.
    QJM : monthly journal of the Association of Physicians, 2001, Volume: 94, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; D

2001
Colorectal cancer presenting with a cutaneous metastatic lesion on the scalp.
    Cutis, 1995, Volume: 55, Issue:1

    Topics: Adenocarcinoma; Colorectal Neoplasms; Diagnosis, Differential; Humans; Male; Middle Aged; Scalp; Ski

1995

Trials

3 trials available for salicylic acid and Colorectal Neoplasms

ArticleYear
Serum salicylate levels and risk of recurrent colorectal adenomas.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2011, Volume: 20, Issue:4

    Topics: Adenoma; Calcium, Dietary; Colorectal Neoplasms; Dietary Supplements; Female; Humans; Male; Middle A

2011
Urinary salicylate excretion in subjects eating a variety of diets shows that amounts of bioavailable salicylates in foods are low.
    The American journal of clinical nutrition, 1996, Volume: 64, Issue:5

    Topics: Adult; Biological Availability; Cardiovascular Diseases; Colorectal Neoplasms; Diet; Female; Humans;

1996
Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose.
    Journal of the National Cancer Institute, 1997, Aug-06, Volume: 89, Issue:15

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Colorectal Neoplasms; Drug Administr

1997

Other Studies

11 other studies available for salicylic acid and Colorectal Neoplasms

ArticleYear
Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study.
    Nutrients, 2021, 11-21, Volume: 13, Issue:11

    Topics: Aspirin; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Genome-Wide Association Study; Ge

2021
Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells.
    Biochemical and biophysical research communications, 2022, 11-05, Volume: 628

    Topics: Aspirin; Colorectal Neoplasms; Cyclin-Dependent Kinase 4; Humans; Prospective Studies; Ribosomal Pro

2022
Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer.
    International journal of oncology, 2017, Volume: 51, Issue:6

    Topics: Acetylation; Anticarcinogenic Agents; Aspirin; CDC2 Protein Kinase; Colorectal Neoplasms; Cyclin B1;

2017
Aspirin for cancer is no mere antiplatelet prototype. There is potential in its ancient roots.
    Medical hypotheses, 2016, Volume: 94

    Topics: Animals; Aspirin; Blood Platelets; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Gastrointestinal

2016
A high performance liquid chromatography system for quantification of hydroxyl radical formation by determination of dihydroxy benzoic acids.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1996, Volume: 5, Issue:4

    Topics: Chromatography, High Pressure Liquid; Colorectal Neoplasms; Humans; Hydroxybenzoates; Hydroxyl Radic

1996
NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species.
    Biochimica et biophysica acta, 1999, Jan-11, Volume: 1448, Issue:3

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antioxidants; Apoptosis; Butyra

1999
Salicylic acid: one more reason to eat your fruits and vegetables.
    Journal of the American Dietetic Association, 2001, Volume: 101, Issue:12

    Topics: Arteriosclerosis; Cardiovascular Diseases; Colorectal Neoplasms; Condiments; Diet, Vegetarian; Food

2001
Cutaneous metastasis to the scalp as the primary presentation of colorectal adenocarcinoma.
    Dermatology online journal, 2017, Nov-15, Volume: 23, Issue:11

    Topics: Adenocarcinoma; Biopsy; Colorectal Neoplasms; CREST Syndrome; Female; Head and Neck Neoplasms; Human

2017
Atypical metastatic presentations in colorectal cancer: a case series.
    Clinical colorectal cancer, 2014, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Colorectal Neoplasms; Female; Humans; Male; Mandibular Neoplasms; Pancr

2014
Choroidal and skin metastases from colorectal cancer.
    World journal of gastroenterology, 2016, Nov-21, Volume: 22, Issue:43

    Topics: Adenocarcinoma; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Biopsy; Capecitabine; C

2016
Synchronous dural and cutaneous metastases along the distribution of the external carotid artery.
    British journal of neurosurgery, 1994, Volume: 8, Issue:5

    Topics: Adult; Carotid Artery, External; Cerebellar Neoplasms; Colorectal Neoplasms; Dura Mater; Humans; Mal

1994