salicylic acid and Acantholysis Bullosa

salicylic acid has been researched along with Acantholysis Bullosa in 8 studies

Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).

Research

Studies (8)

Authors

Clinical Trials (3)

Trial Overview

Trial Outcomes

Average Steps Per Day Assessed by FitBit® / Pedometer

Average number of steps walked per day from baseline to the end of each treatment. (NCT02960997)
Timeframe: 12 weeks

Trough Concentration of Sirolimus

Trough measurements were taken prior to topical sirolimus administration at the week 12 study visit. (NCT02960997)
Timeframe: Week 12

5-D Pruritus Scale Score

The 5-D Pruritus Scale is a 1-page, 5-question tool used in clinical trials to assess 5 dimensions of background itch: degree, duration, direction, disability, and distribution. Each question corresponds to 1 of the 5 dimensions of itch; participants were to rate their symptoms over the preceding 2-week period on a 1 to 5 scale, with 5 being the most affected. After the summation of individual score, the total score ranges from 5 (least affected) to 25 (most affected). Data are reported per intervention. (NCT02960997)
Timeframe: Week 0 and week 12 of the respective treatment period

Child Dermatological Quality of Life Questionnaire Score

Quality of Life-Epidermolysis Bullosa (QOLEB) Questionnaire specifically designed for people with EB. The QOLEB can be used to identify everyday life occurrences negatively affected by EB. It assesses change in quality of life over time, an important measure when assessing the success of new treatments for EB. Scores from 0 to 51, with higher scores indicate greater impact of EB on quality of life. Data are reported per intervention. (NCT02960997)
Timeframe: Week 0 and week 12 of the respective treatment period

Epidermolysis Bullosa Disease Activity and Scarring Index (EBDASI) Disease Severity Scale Score

The EBDASI is a validated scoring system that objectively quantifies the severity of EB affecting the entire body. It has been designed to evaluate the response to new therapies for the treatment of EB. Scores range from 0 (absent of EB) to 10 (entire area involved). Data are reported per intervention. (NCT02960997)
Timeframe: Week 0 and week 12 of the respective treatment period

Foot Health Status Questionnaire, Foot Function Domain Score

Foot function was assessed utilizing the validated Foot Health Status Questionnaire (FHSQ). Low Score (0) means severely limited in performing a broad range of physical activities. High Score (100) means can perform all desired physical activities. Data are reported per intervention. (NCT02960997)
Timeframe: Week 0 and week 12 of the respective treatment period

Foot Health Status Questionnaire, Physical Activity Domain Score

Physical Activity was assessed utilizing the validated Foot Health Status Questionnaire (FHSQ). Low Score (0) means severely limited in performing a broad range of physical activities. High Score (100) means can perform all desired physical activities. Data are reported per intervention. (NCT02960997)
Timeframe: Week 0 and week 12 of the respective treatment period

Reviews

4 reviews available for salicylic acid and Acantholysis Bullosa

Other Studies

4 other studies available for salicylic acid and Acantholysis Bullosa