salicylates has been researched along with Weight-Loss* in 3 studies
3 other study(ies) available for salicylates and Weight-Loss
| Article | Year |
|---|---|
An over-the-counter weight-loss supplement with a toxicity that may be unexpectedly difficult to treat.
Topics: Adult; Caffeine; Dietary Supplements; Female; Humans; Hypokalemia; Nonprescription Drugs; Poisoning; Salicylates; Weight Loss | 2012 |
Alleviation of mortality induced by salicylate and stress.
Protection from the deleterious effects of the interaction of environmental stress and salicylate by calcium supplement was investigated in 96 pigmented rats. Within a 2 x 2 x 4 factorial design, rats were assigned to groups defined by: A) ad lib access to 1) plain tap water, or 2) 50 mM calcium chloride solution; B) exposure to stressors consisting of daily 10 h periods of 1) 98 dB SPL noise, or 2) confinement precluding movements; C) daily injections of 233, 350, or 410 mg/kg of sodium salicylate or the saline vehicle. For subjects maintained on tap water, weight loss and mortality increased with salicylate levels, with all subjects dying in the group drinking water and injected with 410 mg/kg. Calcium protected all of the subjects in the noise stress group but not in the confined group. Topics: Administration, Oral; Animals; Calcium; Death; Male; Noise; Rats; Rats, Inbred Strains; Restraint, Physical; Salicylates; Salicylic Acid; Stress, Psychological; Weight Loss | 1994 |
Tinnitus-induced weight loss in rats. An animal model for tinnitus research.
Growing rats were exposed to noise and/or tinnitus-producing drugs (sodium salicylate, quinine, gentamycin). Growth inhibition or weight loss was absent or significantly lower in the noise-only and salicylate-only/quinine-only groups than in the groups exposed to both noise and drugs. In the gentamycin groups, initially the same trend was found, but general toxicity soon prevailed, leading to heavy weight losses in both groups. The findings clearly favor the hypothesis that tinnitus-induced stress may be the cause for this effect. The experimental set-up thus could serve as an animal model for tinnitus research. In humans, high doses of salicylate or quinine should be avoided in persons exposed to elevated noise levels. Topics: Animals; Disease Models, Animal; Female; Gentamicins; Growth Disorders; Noise; Pilot Projects; Quinine; Rats; Rats, Inbred Strains; Salicylates; Stress, Physiological; Tinnitus; Weight Loss | 1991 |