salicylates and Uterine-Hemorrhage

Topics: Administration, Topical; Aged; Female; Humans; Male; Prothrombin Time; Salicylates; Uterine Hemorrhage; Warfarin

6.6% of all Australian patients attending an antenatal clinic were found to be taking salicylate preparations regularly, most commonly in powder form and almost always as self-medication. In this group of salicylate takers there was an increased incidence of anaemia, anti-partum and post-partum haemorrhage, prolonged gestation, complicated deliveries, and perinatal mortality compared with non-takers. These findings suggest that regular salicylate consumption has detrimental effects in pregnancy. Routine antenatal urinary screening for salicylate in pregnancy is recommended.

Topics: Adolescent; Adult; Age Factors; Anemia; Female; Fetal Death; Humans; Infant, Newborn; Obstetric Labor Complications; Parity; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Pregnancy, Prolonged; Prospective Studies; Salicylates; Self Medication; Time Factors; Uterine Hemorrhage

Topics: Abnormalities, Drug-Induced; Animals; Autonomic Nervous System; Bicarbonates; Chlorpromazine; Embryonic and Fetal Development; Female; Immobilization; Phenobarbital; Pregnancy; Pressure; Rats; Reserpine; Salicylates; Uterine Hemorrhage; Uterus