salicylates and Respiratory-Insufficiency

Topics: Aminobutyrates; Aminophylline; Carbonic Anhydrase Inhibitors; Central Nervous System Stimulants; Drug Therapy; Flavones; Humans; Lung Diseases; Lung Diseases, Obstructive; Nikethamide; Respiratory Insufficiency; Respiratory System Agents; Salicylates; Thiazoles; Toxicology; Tromethamine

Topics: Abdomen; Acidosis; Diagnosis, Differential; Humans; Infant; Lethargy; Male; Poisoning; Renal Dialysis; Respiratory Insufficiency; Salicylates; Tachypnea

Topics: Humans; Intubation, Intratracheal; Respiratory Insufficiency; Salicylates

Topics: Aged; Arrhythmias, Cardiac; Diazepam; Female; Heart Arrest; Humans; Male; Middle Aged; Respiratory Insufficiency; Salicylates

The case of a patient who developed severe acute respiratory failure during therapy for salicylate intoxication is described. The individual with aspirin overdose is at risk for this complication because of the potential for treatment modalities to cause or worsen lung edema initiated by the effects of salicylates on the pulmonary capillary bed.

Topics: Adult; Diuresis; Female; Humans; Pulmonary Edema; Renal Dialysis; Respiratory Insufficiency; Salicylates

Topics: Asthma; Congenital Hypothyroidism; Ephedrine; Female; Goiter; Humans; Hypothyroidism; Infant, Newborn; Iodides; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pregnancy Complications; Respiratory Insufficiency; Salicylates; Theophylline

The plasma protein binding of a representative acidic drug, salicylate, and a representative basic drug, quinidine, has been studied in patients with several diseases that are sometimes associated with uraemia or a change in serum albumin level. Decreased plasma protein binding of salicylate was observed in plasma from patients with uraemia and liver disease. Low albumin levels in these patients could only account inpart for the decreased binding. On the other hand, salicylate binding to plasma proteins appeared to be increased in patients with hypoxia. Decreased plasma protein binding of quinidine was observed in some patients with uraemia and in the majority of patients with liver disease.

Topics: Adult; Aged; Blood Proteins; Chronic Disease; Humans; Kidney Failure, Chronic; Liver Diseases; Middle Aged; Protein Binding; Quinidine; Respiratory Insufficiency; Salicylates

Topics: Abdominal Injuries; Adrenal Cortex Hormones; Anti-Bacterial Agents; Anuria; Blood Gas Analysis; Blood Volume; Electrocardiography; Humans; Hypotension; Hypothermia, Induced; Kinetics; Oxygen; Respiratory Insufficiency; Salicylates; Shock; Shock, Hemorrhagic; Shock, Traumatic; Thoracic Injuries; Urination; Vascular Resistance; Vasodilator Agents; Venous Pressure

Topics: Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alkalosis; Alkalosis, Respiratory; Arteries; Asthma; Carbon Dioxide; Education, Medical; Female; Heart Arrest; Humans; Hydrogen-Ion Concentration; Infant; Keto Acids; Kidney Failure, Chronic; Male; Mathematics; Middle Aged; Pulmonary Edema; Respiratory Insufficiency; Salicylates; Teaching

Topics: Arthritis; Arthritis, Rheumatoid; Collagen Diseases; Gold; Humans; Otorhinolaryngologic Diseases; Phenylbutazone; Respiratory Insufficiency; Rheumatic Fever; Salicylates; Tonsillectomy

Topics: Antidotes; Barbiturates; Cholinesterase Inhibitors; Glutethimide; Humans; Hypoventilation; Meprobamate; Morphine; Myasthenia Gravis; Poisoning; Pulmonary Atelectasis; Pulmonary Edema; Respiration, Artificial; Respiratory Insufficiency; Salicylates; Tetanus; Therapeutics; Toxicology; Tracheotomy