salicylates and Remission--Spontaneous

Sixty-four patients with proven ulcerative colitis who had been maintained on sulphasalazine as their sole form of treatment for a minimum period of one year were entered into a controlled trial of sulphasalazine versus dummy tablets for a period of six months. All the patients admitted were not only symptom-free but also showed no evidence of inflammation on sigmoidoscopy and rectal biopsy. A patient was judged to have relapsed when there was a recurrence of colitic symptoms accompanied by sigmoidoscopic and histological evidence of inflammation. The patients who received dummy tablets had more than four times the relapse rate of those receiving sulphasalazine. The results were similar in patients who had been on maintenance treatment with sulphasalazine for less than three years before entry into the trial and in those who had been on this treatment for more than three years. It is concluded that maintenance treatment of ulcerative colitis with sulphasalazine should be continued indefinitely unless contraindicated by side effects.

Topics: Biopsy; Blood Cell Count; Blood Sedimentation; Clinical Trials as Topic; Colitis, Ulcerative; Headache; Hemoglobins; Humans; Inflammation; Nausea; Placebos; Prednisolone; Psychology; Rectum; Remission, Spontaneous; Salicylates; Sigmoidoscopy; Sulfasalazine

Topics: Ataxia; Bismuth; Confusion; Delirium; Dyspepsia; Gait; Humans; Male; Memory Disorders; Middle Aged; Organometallic Compounds; Remission, Spontaneous; Salicylates; Tremor

The role played by dietary chemical factors in the pathogenesis of chronic idiopathic urticaria (CIU) was assessed in seventy-six patients by challenge Stable remission was first established by using an empirically established 'exclusion diet'. A diet modified to exclude those chemicals giving a positive response to challlenge was demonstrated to be of therapeutic value for time periods of up to 18 months. Re-testing twelve patients at 12 months indicated that most patients positive to salicylate or benzoate challenge retained this pattern of reactivity.

Topics: Adolescent; Adult; Aged; Benzoates; Child; Chronic Disease; Female; Humans; Male; Middle Aged; Penicillins; Remission, Spontaneous; Salicylates; Tartrazine; Urticaria; Yeast, Dried

Topics: Adrenal Cortex Hormones; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Pregnancy; Remission, Spontaneous; Salicylates

Topics: Adult; Anti-Bacterial Agents; Arthritis; Behcet Syndrome; Humans; Male; Middle Aged; Recurrence; Remission, Spontaneous; Salicylates

Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Ambulatory Care; Betamethasone; Female; Follow-Up Studies; Home Nursing; Hospitalization; Humans; Male; Prognosis; Psoriasis; Remission, Spontaneous; Salicylates; Tars; Time Factors; Ultraviolet Therapy

Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Child; Drug Combinations; Drug Evaluation; Female; Hexachlorophene; Humans; Male; Middle Aged; Remission, Spontaneous; Salicylates; Sulfur

Topics: Evaluation Studies as Topic; Hodgkin Disease; Humans; Remission, Spontaneous; Salicylates; Sodium

Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Drug Combinations; Female; Follow-Up Studies; Humans; Infant; Male; Middle Aged; Ointments; ortho-Aminobenzoates; Petrolatum; Psoriasis; Remission, Spontaneous; Salicylates; Sex Factors; Time Factors