salicylates and Periodontal-Diseases

Topics: Anti-Infective Agents, Local; Chlorhexidine; Dental Implants; Dental Plaque; Drug Combinations; Gingivitis; Humans; Mouthwashes; Oils, Volatile; Oral Hygiene; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Index; Periodontal Pocket; Salicylates; Terpenes

Periodontal diseases are a group of related inflammatory disorders, initiated by dental plaque and causing destruction of the supporting structures of the teeth. Although the inflammatory response is a fundamental defence mechanism against bacterial infection, its persistence over a long period of time may extensively damage the periodontal tissues: cementum, alveolar bone, periodontal ligament and dentogingival tissues. These disorders, despite recent improvements in oral health are still a major cause of tooth loss in patients over 35 years of age.

Topics: Adult; Anti-Infective Agents, Local; Cetylpyridinium; Child; Child, Preschool; Chlorhexidine; Chlorine; Dental Plaque; Drug Combinations; Fluorides; Gingivitis; Humans; Iodine; Middle Aged; Mouthwashes; Oxides; Periodontal Diseases; Povidone; Salicylates; Terpenes; Triclosan

Topics: Alkaloids; Bacteremia; Benzophenanthridines; Chlorhexidine; Dental Devices, Home Care; Dental Plaque; Drug Combinations; Gingivitis; Humans; Hydrogen Peroxide; Isoquinolines; Periodontal Diseases; Root Planing; Salicylates; Terpenes; Therapeutic Irrigation; Tin Fluorides

Various hypotheses have been introduced and discussed in the past decade to explain the aetiology of caries and paradontopathies: Non-specific/group-specific/specific plaque hypothesis, exogenic plaque hypothesis, ecological change theory. Principles and strategies of chemotherapy for dental plaque-related ailments are treated on the basis of these theories.

Topics: Amines; Anti-Bacterial Agents; Cariostatic Agents; Chlorhexidine; Dental Caries; Dental Plaque; Drug Combinations; Fluorides; Humans; Periodontal Diseases; Salicylates; Terpenes; Tin Fluorides

This 3-month double-blind randomized placebo-controlled study evaluated the clinical and microbial effects of an essential oil mouth rinse used as an adjunct to mechanical plaque control by patients in supportive periodontal care.. Fifty patients were randomly allocated to an essential oil group (Listerine(®) Coolmint; Johnson & Johnson, New Brunswick, NJ, USA) or placebo group to rinse twice per day as an adjunct to mechanical plaque control. At baseline and after 3 months, plaque index (PI), gingivitis index (GI), probing pocket depth, bleeding on probing (BoP) and clinical attachment level were registered. Subgingival plaque samples were collected for the detection and quantification of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Micromonas micros, Prevotella intermedia, Fusobacterium genus and Streptococcus mutans by means of real-time PCR (qPCR). Patient's compliance, satisfaction and side effects were registered.. Twenty-three patients in the essential oil group (mean age: 57) and 21 in the placebo group (mean age: 55) with acceptable oral hygiene at intake (mean PI <1.5 on a scale of 5) adhered to the study protocol. Gingivitis index, PI and BoP significantly reduced over time (P ≤ 0.029); however, between group analyses revealed no significant differences. There was no significant change over time neither in detection frequency nor load for any of the microbiota. Daily rinsing with an essential oil rinse was found safe and perceived beneficial by the patients.. Patients in supportive periodontal care who are fairly compliant with oral hygiene may not benefit from additional mouth rinsing using an essential oil solution.

Topics: Adult; Aged; Aged, 80 and over; Aggregatibacter actinomycetemcomitans; Anti-Infective Agents, Local; Bacteroides; Dental Plaque; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Fusobacterium; Gingival Hemorrhage; Humans; Male; Middle Aged; Mouthwashes; Oils, Volatile; Patient Satisfaction; Peptostreptococcus; Periodontal Attachment Loss; Periodontal Diseases; Periodontal Pocket; Placebos; Porphyromonas gingivalis; Prevotella intermedia; Salicylates; Streptococcus mutans; Terpenes; Treatment Outcome; Treponema denticola

Topics: Dental Plaque; Drug Combinations; Female; Gingivitis; Humans; Middle Aged; Mouthwashes; Osteoporosis, Postmenopausal; Periodontal Diseases; Pilot Projects; Salicylates; Terpenes

Topics: Adult; Analysis of Variance; Cross-Over Studies; Dental Plaque Index; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Mouthwashes; Periodontal Diseases; Periodontal Index; Postoperative Care; Salicylates; Terpenes

The effectiveness of diflunisal as a preoperative medication to reduce pain following periodontal surgery was evaluated. Fifty patients were divided into two groups in a double-blind random manner: Group one received preoperative difunisal and Group two received preoperative placebo. The preoperative diflunisal group reported significantly less discomfort (P less than 0.05) than the preoperative placebo group and used rescue medication significantly less often (P less than 0.01). Therapeutic doses of diflunisal, given presurgically, are significantly more effective than placebo in limiting postoperative pain associated with periodontal surgery.

Topics: Adolescent; Adult; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Middle Aged; Pain, Postoperative; Periodontal Diseases; Placebos; Premedication; Random Allocation; Salicylates

Topics: Double-Blind Method; Fluorides; Humans; Hydroxybenzoates; Mouthwashes; Periodontal Diseases; Placebos; Salicylates

Evaluation of the clinical efficacy of the drug holisal» according to the results of domestic and foreign studies on modern methods for treatment of inflammatory diseases of the oral mucosa mouth and periodontium.. The study method was a comparative analysis of data obtained by various authors. The literature search was conducted on PubMed (www.ncbi.nlm.nih.gov), eLibrary (elibrary.ru) and ScienceDirect (www.sciencedirect.com).. The drug Cholisal reduces the duration of treatment, allows to increase the period of remission of the disease. It also promotes pain relief and accelerated mucosal epithelialization of the mouth mucosa.. Clinical studies of the drug Cholisal have shown that a wide range of its pharmacological action ensures the effectiveness of treatment of inflammatory diseases of the oral mucosa and periodontium by a combination of analgesic, antimicrobial, anti-inflammatory, and antifungal effects.. Оценка клинической эффективности применения препарата Холисал по результатам отечественных и зарубежных исследований, посвященных современным методам лечения воспалительных заболеваний слизистой оболочки полости рта и пародонта.. Методом изучения явился сравнительный анализ представленных публичных данных, полученных различными авторами. Проведен поиск литературы по базе PubMed (www.ncbi.nlm.nih.gov), eLibrary (elibrary.ru) и ScienceDirect (www.sciencedirect.com).. Препарат Холисал сокращает сроки лечения, позволяет увеличить период ремиссии заболевания. Способствует купированию болевого синдрома и ускоренной эпителизации слизистой оболочки рта.. Клинические исследования препарата Холисал показали, что широкий диапазон его фармакологического действия обеспечивает эффективность лечения воспалительных заболеваний слизистой оболочки полости рта и пародонта, когда одновременно требуется сочетание анальгезирующего, противомикробного, противовоспалительного, противогрибкового воздействий.

Topics: Humans; Mouth Mucosa; Periodontal Diseases; Periodontium; Salicylates; Stomatitis, Aphthous

Dental plaque is a biofilm that forms naturally on the surfaces of exposed teeth and other areas of the oral cavity. It is the primary etiological factor for the most frequently occurring oral diseases, such as dental caries and periodontal diseases. Specific, nonspecific, and ecologic plaque hypothesis explains the causation of dental and associated diseases. Adequate control of biofilm accumulation on teeth has been the cornerstone of prevention of periodontitis and dental caries. Mechanical plaque control is the mainstay for prevention of oral diseases, but it requires patient cooperation and motivation; therefore, chemical plaque control agents act as useful adjuvants for achieving the desired results. Hence, it is imperative for the clinicians to update their knowledge in chemical antiplaque agents and other developments for the effective management of plaque biofilm-associated diseases. This article explores the critical analysis of various chemical plaque control strategies and the current trends in the control and prevention of dental plaque biofilm.

Topics: Aloe; Benzhydryl Compounds; Biofilms; Cetylpyridinium; Chlorhexidine; Dental Plaque; Dextranase; Drug Combinations; Humans; Lippia; Morpholines; Periodontal Diseases; Phenols; Plant Extracts; Povidone-Iodine; Propolis; Salicylates; Terpenes

The aim of our research was to evaluate efficiency of medicine Cholisal in complex treatment of periodontitis. During the research 36 patients with periodontitis (from 18 to 36 years old) were examined and treated. The patients were divided into 3 groups according to severity of periodontitis. Each group included 12 patients. For studying the efficiency of treatment both objective and subjective data was used. In case of mild severity of disease clinical indices were: HI=2,1+/-0,75; Ghi=1,4+/-0,67; Gi=1,7+/-0,78, PI=0,8+/-0,34. In case of moderate severity of disease clinical indices were: HI=2,57+/-1,02; GHI=2,18+/-0,81; GI=1,95+/-0,8, PI=3,9+/-1,1. In case of severe disease - HI=3,9+/-1,25, GHI=2,5+/-0,8, GI=2,9+/-1,2, PI=7,8+/-1,62. Clinical study has shown that Cholisal enables successful treatment of periodontitis. It has prolonged, antiinflamatory, deodorant and analgesic effect. Our investigation revealed that xolisale can be recommended in complex treatment of periodontal disease.

Topics: Adolescent; Adult; Anti-Bacterial Agents; Cellulose; Choline; Glycerol; Humans; Oral Hygiene; Periodontal Diseases; Salicylates; Severity of Illness Index

Topics: Administration, Topical; Anti-Bacterial Agents; Chlorhexidine; Drug Combinations; Drug Delivery Systems; Humans; Periodontal Diseases; Salicylates; Terpenes; Tin Fluorides

In Part I of this two-part series, the author described a comprehensive nonsurgical program for the general practitioner, including the use of the DNA probe, various plaque control modalities, nonsurgical therapy, and the limitations of the program. In Part II, the author describes verbal skills that can be helpful in discussing periodontal therapy with patients, along with antimicrobial therapy, treating the periodontal maintenance patient with early signs of breakdown, and communicating with the periodontist to create positive results for the patient, the general practitioner's office, and the periodontist's office.

Topics: Chlorhexidine; Dental Prophylaxis; Dentist-Patient Relations; Drug Combinations; Humans; Patient Acceptance of Health Care; Periodontal Diseases; Referral and Consultation; Salicylates; Terpenes

Topics: Gingival Diseases; Periodontal Diseases; Salicylates; Sulfonic Acids; Trichloroacetic Acid