salicylates and Periapical-Diseases

Differences in bone density before and after endodontic treatment were examined in teeth with periapical lesions in Hounsfield units (HUs) by using cone beam computed tomography (CBCT).. Sixteen patients requiring endodontic treatment for periapical lesions underwent CBCT scan before and after treatment. Their bone densities were calculated in HUs. The study included 16 lesions measuring 8-10 mm in diameter. HU measurements were taken from an area of 2.25 mm(2) on the CBCT images where the bone density was lowest, before and after treatment.. The initial and final measurements were compared statistically by using paired samples statistics at the 5% significance level.. The results of this study support the use of CBCT to measure bone density before and after endodontic treatment.

Topics: Adolescent; Adult; Alveolar Bone Loss; Alveolar Process; Bone Density; Bone Regeneration; Calcium Hydroxide; Cone-Beam Computed Tomography; Cuspid; Follow-Up Studies; Gutta-Percha; Humans; Incisor; Maxilla; Periapical Diseases; Root Canal Filling Materials; Root Canal Preparation; Root Canal Therapy; Salicylates; Wound Healing; Young Adult

The objective of this study was to evaluate the apical and periapical repair after endodontic treatment of teeth with pulp necrosis and a chronic periapical lesion in dogs. Seventy-two root canals from four mongrel dogs were submitted to biomechanical preparation, using 5.25% sodium hypochlorite or 2% chlorhexidine digluconate as the irrigating solution. The root canals were subsequently either filled immediately with Sealapex, using active lateral gutta-percha condensation, or a calcium hydroxide root canal dressing was applied for 15 days before filling with Sealapex. After 210 days, the animals were killed by anesthetic overdose, and the obtained histological sections were stained with hematoxylin and eosin for optical microscopic analysis of apical and periapical repair. There was better histological repair in the groups with the root canal dressing (p < 0.05) than the groups with immediate obturation. Comparing the immediate obturation groups, irrigation with chlorhexidine solution resulted in better repair than sodium hypochlorite.

Topics: Animals; Bone Resorption; Calcium Hydroxide; Chlorhexidine; Dental Pulp Necrosis; Disease Models, Animal; Disinfectants; Dogs; Female; Gutta-Percha; Male; Periapical Diseases; Periapical Periodontitis; Periapical Tissue; Periodontal Ligament; Root Canal Filling Materials; Root Canal Irrigants; Root Canal Obturation; Root Canal Preparation; Root Canal Therapy; Root Resorption; Salicylates; Sodium Hypochlorite; Statistics as Topic; Statistics, Nonparametric; Time Factors; Wound Healing

Topics: Adolescent; Adult; Aged; Child; Diflunisal; Humans; Middle Aged; Mouth; Pain, Postoperative; Periapical Diseases; Salicylates; Tooth Extraction