salicylates has been researched along with Orthomyxoviridae-Infections* in 1 studies
1 other study(ies) available for salicylates and Orthomyxoviridae-Infections
| Article | Year |
|---|---|
Inhibition of fatty acid beta oxidation by influenza B virus and salicylic acid in mice: implications for Reye's syndrome.
Injection of concentrated influenza B/Lee/40 virus into 4-week-old Balb C mice resulted in 60% inhibition of 14C-palmitate oxidation in isolated hepatic mitochondria. Oral feeding of carnitine to infected mice prevented the inhibition of fatty acid oxidation. High concentrations of salicylic acid given orally also inhibited 14C-palmitate oxidation. Serum free fatty acid concentrations of infected mice and of those fed salicylic acid were significantly higher than in control mice. A combination of low-dose virus and low-dose salicylic acid inhibited palmitate oxidation, suggesting an additive effect on the metabolic derangement when the two agents were present simultaneously. Topics: Animals; Influenza B virus; Mice; Orthomyxoviridae Infections; Oxidation-Reduction; Palmitates; Palmitic Acids; Reye Syndrome; Salicylates; Salicylic Acid | 1988 |