salicylates and Intestinal-Diseases

Ulcers of the small bowel are documented in a patient after intake of salsalate. Rapid clinical and endoscopic improvement occurred on discontinuation of administration of the drug. Endoscopic features suggested the direct effect of a tablet dissolving in the proximal part of the small bowel. To my knowledge, this is the first report of small-bowel ulcerations associated with the newer form of salicylates that bypass the stomach for their absorption.

Topics: Female; Humans; Intestinal Diseases; Intestine, Small; Middle Aged; Osteoarthritis; Peptic Ulcer; Salicylates; Ulcer

Topics: Adolescent; Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Colchicine; Genetics, Medical; Gout; Intestinal Diseases; Intestinal Obstruction; Intestine, Small; Kidney Diseases; Pathology; Salicylates; Substance Withdrawal Syndrome; Substance-Related Disorders; Toxicology; Uremia; Uricosuric Agents

Topics: Anticoagulants; Bismuth; Chemical and Drug Induced Liver Injury; Chlorothiazide; Drug Therapy; Esophagus; Gastroenterology; Hepatitis; Intestinal Diseases; Mercury Poisoning; Morphine; Mouth; Pancreas; Phenylbutazone; Phenytoin; Reserpine; Salicylates; Steroids; Stomach; Tooth; Toxicology