salicylates and Dermatitis--Seborrheic

Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Candidiasis; Child, Preschool; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Occupational; Dermatitis, Seborrheic; Eczema; Environmental Exposure; Female; Glucocorticoids; Humans; Hyperhidrosis; Infant; Male; Photosensitivity Disorders; Saccharomyces cerevisiae; Salicylates; Steroids; Sulfur

Dandruff is a common scalp disorder affecting almost half of the post-pubertal population of any ethnicity and both genders. It is one of the major reasons for patients to consult a dermatologist and it is the cause of significant psychological and social distress.. The aim of this open study was to evaluate the benefit of a 4-week treatment with a shampoo containing 0.1% lipohydroxyacid (LHA) and 1.3% salicylic acid on the scalp condition and on the quality of life of 275 volunteers with seborrheic dermatitis (SD) (n = 226) or light-to-moderate scalp psoriasis (SP) (n = 49).. The clinical benefit of the treatment was assessed by scoring the following parameters, i.e., severity of the dermatosis, scaling, itching, excoriations, and superficial burning sensation. The impact on the quality of life was assessed using the Scalpdex, a questionnaire specially developed by Chen et al. for patients with scalp dermatitis, which includes 23 questions regarding the symptoms, functioning and emotions affected by scalp dermatosis.. The shampoo used in this study was well tolerated. After a 4-week treatment, dermatologists noticed a significant clinical improvement of all the scalp parameters evaluated (i.e., the composite lesional score was improved in 91% and 77% of the patients with SD or SP respectively). The symptoms, functioning and emotions scores of quality of life were also significantly improved in relation to the improvement of scalp condition.. This study not only allowed a better understanding of the SD and SP patient's profile but also demonstrated that the shampoo evaluated is a convenient, efficient, safe, and well-tolerated cosmetic treatment of SD and light-to-moderate SP improving greatly the quality of life of the treated patients.

Topics: Administration, Cutaneous; Adult; Chronic Disease; Dermatitis, Seborrheic; Female; Hair Preparations; Humans; Keratolytic Agents; Male; Middle Aged; Psoriasis; Quality of Life; Salicylates; Scalp Dermatoses; Severity of Illness Index; Surveys and Questionnaires; Treatment Outcome

The success of a dandruff treatment depends not only on the ability of a shampoo to control dandruff, but also on patient compliance, which is closely linked to the cosmetic attributes of the product.. The aim of this study was to compare efficacy, tolerance, and cosmetic properties of a LHA Shampoo [containing 0.1% lipohydroxy acid (LHA) and 1.3% salicylic acid] to a CPO shampoo [containing 1.5% ciclopiroxolamine (CPO), 3% salicylic acid, and 0.5% menthol] in subjects with seborrheic dermatitis (SD) of the scalp.. One hundred subjects with mild to moderate scalp SD were randomized to receive either the LHA shampoo or the CPO shampoo every 2 days for 4 weeks. Efficacy and tolerance were evaluated at days 0, 14, and 28.. The LHA and the CPO shampoo both decreased symptoms of scale, erythema, itching, cutaneous discomfort, and dryness from baseline to day 28. A higher percentage of patients showed improvement in the group treated with the LHA formulation than in the group treated with the CPO formulation, but the difference did not reach statistical significance. At day 28, the tolerance and the global efficacy of the LHA shampoo were significantly better (P = 0.03 and P = 0.01, respectively) than those of the CPO shampoo. Furthermore, the cosmetic acceptability was better or significantly better for all the endpoints evaluated for the LHA shampoo (P = 0.02 for cleaning, P = 0.04 for lathering).. In conclusion, these results demonstrated that the lipohydroxy acid shampoo evaluated in this study is a more convenient, efficient, safe, and well-tolerated cosmetic treatment for mild-to-moderate seborrheic dermatitis of the scalp than a ciclopiroxolamine shampoo.

Topics: Adult; Ciclopirox; Dermatitis, Seborrheic; Female; Hair Preparations; Humans; Male; Pyridones; Salicylates; Scalp Dermatoses

Efficacy and tolerance of an alcoholic solution containing 0.64 mg betamethasone-dipropionate plus 20 mg salicylic acid (Diprosalic Solution) were compared with an alcoholic solution containing 0,64 mg betamethasone-dipropionate in a 3 week double blind study in 100 patients with psoriasis and other steroid-responsive dermatoses of dry nature, comprising scalp and other hairy and non-hairy areas of the body. This double blind study was followed by a 3 week open study in another 100 patients with similar diagnosis, using Diprosalic Solution only. Although the therapeutic results of the double blind study showed no significant differences between both treatment groups, distinct advantages of the drug containing salicylic acid could be clearly demonstrated, such as: 1. More rapid onset of action, 2. rapid clearing of scaling, pruritus and inflammation, 3. these advantages are in compliance with the fact that topically applied salicylic acid softens keratin, loosens cornified epithelium and desquamates the epidermis, making the underlying layers more accessible to the antiinflammatory steroid.

Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Clinical Trials as Topic; Dermatitis; Dermatitis, Seborrheic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Eczema; Female; Glucocorticoids; Humans; Male; Middle Aged; Psoriasis; Salicylates; Salicylic Acid

Topics: Clinical Trials as Topic; Dermatitis, Seborrheic; Double-Blind Method; Humans; Salicylates; Scalp Dermatoses; Selenium; Soaps; Sulfur; Zinc

A methyl salicylate-buffered, croton oil-containing 50% salicylic acid ointment peel, following pretreatment with topical tretinoin and localized 20% trichloroacetic acid, is extremely effective for removal of lentigines, pigmented keratoses, and actinically damaged skin from the dorsum of the hands and forearms. The ease of application, uniform results, decreased risk of scarring, and one-time application of this peel, in comparison with other methods used for treatment of these aging-skin changes, warrants consideration by the dermatologic surgeon.

Topics: Aged; Bandages; Chemexfoliation; Dermatitis, Seborrheic; Female; Forearm; Hand Dermatoses; Humans; Keratosis; Lentigo; Ointments; Pigmentation Disorders; Salicylates; Salicylic Acid; Tretinoin; Trichloroacetic Acid

One hundred patients with facial seborrheic dermatitis and 42 control subjects were studied. The number of periodic acid-Schiff-positive Pityosporum ovale yeast cells in skin scrapings per high-power field were counted and designated 1 + to 4 +. Our data indicate a correlation between the density of P. ovale and the clinical severity of seborrheic dermatitis, both before and after therapy with a precipitated sulfur/salicyclic acid shampoo. The data support the concept that yeast contributes to the pathogenesis of seborrheic dermatitis.

Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Dermatitis, Seborrheic; Facial Dermatoses; Follow-Up Studies; Humans; Malassezia; Male; Middle Aged; Salicylates; Staining and Labeling; Sulfur

Essentials of the author's own way of therapeutical proceeding are: in cases of low inflammatory seborrheic dermatitis, ointments containing salicylic acid and sulfur; in children, zinc oil and zinc paste with bismuth; in cases of acute seborrheic dermatitis, ointments with glucocorticoids; in seborrheic erythroderma, systemic glucocorticoids.

Topics: Administration, Topical; Anti-Inflammatory Agents; Bismuth; Dermatitis, Seborrheic; Glucocorticoids; Humans; Ointments; Salicylates; Sulfur; Zinc

Recommendations for topical dermatologic therapy of the most common skin diseases in infancy and childhood are given with tabular summaries. They are concerned with diaper dermatitis, seborrhoeic dermatitis, atopic dermatitis, scabies and pediculosis. Special attention is given to topical steroid therapy in seborrhoeic and atopic dermatitis and to the possible neurotoxic side-effects of Lindan, the most effective substance against scabies and pediculosis.

Topics: Administration, Topical; Antifungal Agents; Balneology; Child; Child, Preschool; Cortisone; Dermatitis, Atopic; Dermatitis, Seborrheic; Diaper Rash; Hexachlorocyclohexane; Histamine H1 Antagonists; Humans; Infant; Ointments; Salicylates; Scabies; Skin Diseases; Zinc Oxide

Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Dermatitis, Seborrheic; Diagnosis, Differential; Humans; Hydrocortisone; Infant; Salicylates; Sulfur; Tars

Topics: Age Factors; Dermatitis, Seborrheic; Diagnosis, Differential; Female; Humans; Infant; Poisoning; Salicylates; Skin Absorption

Topics: Dermatitis; Dermatitis, Seborrheic; Drug Combinations; Drug Evaluation; Humans; Pregnadienetriols; Psoriasis; Salicylates; Solutions

Topics: Administration, Topical; Anti-Inflammatory Agents; Dermatitis; Dermatitis, Seborrheic; Dermatologic Agents; Drug Prescriptions; Eczema; Female; Humans; Hydrocortisone; Male; Neomycin; Ointment Bases; Psoriasis; Salicylates; Skin Diseases; Sulfur; Tetracycline

Sebaceous gland activity in the newborn and children is extensive at first in the epidermis, and later decreases owing to defective operation of the sweat glands, circulation changes, growth of the hair, and a predisposition to infection, for which significant treatment is required. In addition to the genetic "typus neurodermiticus", pharmaceutical, alimentary and respiratory allergens and psychological factors may play a part in the appearance of atopical dermatitis. Onset is usually in the 2nd to 6th month and the side of the face and the scalp are affected. The clinical picture varies considerably with age and includes sanious foci covered with scabs on the head and eczema flexurarum. Differences in family history, age and the location of sites will distinguish this form from seborrhoeic dermatitis. Gluteal dermitis is secondary to congestion caused by dampness, rugging and soaking, and the action of stools and urine (bacterial amniogenesis). The main complications of neonatal and infantile impetigo are: glomerulonephritis, exfoliative dermatitis, pulmonary abscess, pulmonitis and osteomyelitis; phlyctenular, serpiginous impetigo with large and small bullae is particularly important. Treatment of neonatal and infantile dermatosis must take account of the fact that increased reabsorption and congestion are contraindications for the local application of corticoids and preparations containing salicylic and boric acid.

Topics: Anti-Bacterial Agents; Child, Preschool; Dermatitis, Atopic; Dermatitis, Seborrheic; Diagnosis, Differential; Diet Therapy; Eczema; Humans; Hypnotics and Sedatives; Impetigo; Infant; Infant, Newborn; Infant, Newborn, Diseases; Neurodermatitis; Nystatin; Oils; Ointments; Salicylates; Skin Diseases

Topics: Acne Keloid; Administration, Topical; Alopecia Areata; Anti-Inflammatory Agents; Dermatitis, Seborrheic; Drug Combinations; Drug Evaluation; Fluocortolone; Glucocorticoids; Humans; Pantothenic Acid; Pregnadienediols; Psoriasis; Salicylates; Scalp Dermatoses; Solutions

Topics: Adrenocorticotropic Hormone; Alopecia; Betamethasone; Dermatitis, Seborrheic; Detergents; Eczema; Female; Hair; Hexachlorophene; Humans; Impetigo; Lice Infestations; Lichen Planus; Male; Psoriasis; Pyridinium Compounds; Salicylates; Scalp Dermatoses; Selenium; Skin Neoplasms; Sulfur; Tinea Capitis

Topics: Arm; Dermatitis, Seborrheic; Drug Combinations; Eczema; Flumethasone; Humans; Leg Dermatoses; Neurodermatitis; Ointments; Pregnanetriol; Prurigo; Salicylates; Skin Absorption; Skin Diseases; Skin Diseases, Infectious

Topics: Cold Temperature; Dermatitis, Contact; Dermatitis, Seborrheic; Eczema; Eczema, Dyshidrotic; Humans; Neurodermatitis; Pityriasis; Salicylates; Zinc

Topics: Adrenal Cortex Hormones; Dermatitis, Seborrheic; Facial Dermatoses; Hair; Humans; Male; Salicylates; Sulfur; Tars

Topics: Adrenal Cortex Hormones; Age Factors; Borates; Child; Child, Preschool; Dermatitis, Exfoliative; Dermatitis, Seborrheic; Diagnosis, Differential; Diaper Rash; Glomerulonephritis; Humans; Impetigo; Infant; Infant, Newborn; Lung Abscess; Neurodermatitis; Osteomyelitis; Pneumonia; Salicylates; Skin Absorption; Skin Diseases

Topics: Dermatitis; Dermatitis, Seborrheic; Drug Combinations; Eczema; Flumethasone; Humans; Ointments; Prurigo; Salicylates; Skin Diseases; Staphylococcus

Topics: Alopecia Areata; Benzalkonium Compounds; Dermatitis, Seborrheic; Granuloma; Humans; Neurodermatitis; Paronychia; Salicylates; Skin Diseases; Triamcinolone Acetonide

Topics: Antifungal Agents; Dandruff; Dermatitis; Dermatitis, Seborrheic; Humans; Salicylates; Scalp Dermatoses; Sebaceous Gland Diseases

Topics: Dermatitis; Dermatitis, Seborrheic; Disease; Humans; Keratolytic Agents; Salicylates; Scalp; Sebaceous Gland Diseases; Skin Diseases

Topics: Dandruff; Dermatitis; Dermatitis, Seborrheic; Salicylates; Salts; Sebaceous Gland Diseases

Topics: Biphenyl Compounds; Dermatitis, Seborrheic; Disease; Salicylates; Scalp; Skin Diseases