salicylates and Cholera

salicylates has been researched along with Cholera* in 5 studies

Trials

1 trial(s) available for salicylates and Cholera

Article	Year
Saccharomyces boulardii and bismuth subsalicylate as low-cost interventions to reduce the duration and severity of cholera. Pathogens and global health, 2015, Volume: 109, Issue:6 We conducted a randomised single-blinded clinical trial of 100 cholera patients in Port-au-Prince, Haiti to determine if the probiotic Saccharomyces cerevisiae var. boulardii and the anti-diarrhoeal drug bismuth subsalicylate (BS) were able to reduce the duration and severity of cholera. Subjects received either: S. boulardii 250 mg, S. boulardii 250 mg capsule plus BS 524 mg tablet, BS 524 mg, or two placebo capsules every 6 hours alongside standard treatment for cholera. The length of hospitalisation plus the number and volume of emesis, stool and urine were recorded every 6 hours until the study subject was discharged (n = 83), left against medical advice (n = 11), or requested removal from the study (n = 6). There were no reported deaths or adverse study-related events. There were no statistically significant differences between the study arms and the outcomes of interest. Topics: Adult; Anti-Bacterial Agents; Antibodies, Bacterial; Bismuth; Cholera; Diarrhea; Disease Outbreaks; Emergency Medical Services; Feces; Female; Fluid Therapy; Haiti; Humans; Length of Stay; Male; Organometallic Compounds; Probiotics; Saccharomyces; Salicylates; Severity of Illness Index; Treatment Outcome; Vibrio cholerae	2015

Article

Year

Saccharomyces boulardii and bismuth subsalicylate as low-cost interventions to reduce the duration and severity of cholera.

Pathogens and global health, 2015, Volume: 109, Issue:6

We conducted a randomised single-blinded clinical trial of 100 cholera patients in Port-au-Prince, Haiti to determine if the probiotic Saccharomyces cerevisiae var. boulardii and the anti-diarrhoeal drug bismuth subsalicylate (BS) were able to reduce the duration and severity of cholera. Subjects received either: S. boulardii 250 mg, S. boulardii 250 mg capsule plus BS 524 mg tablet, BS 524 mg, or two placebo capsules every 6 hours alongside standard treatment for cholera. The length of hospitalisation plus the number and volume of emesis, stool and urine were recorded every 6 hours until the study subject was discharged (n = 83), left against medical advice (n = 11), or requested removal from the study (n = 6). There were no reported deaths or adverse study-related events. There were no statistically significant differences between the study arms and the outcomes of interest.

Topics: Adult; Anti-Bacterial Agents; Antibodies, Bacterial; Bismuth; Cholera; Diarrhea; Disease Outbreaks; Emergency Medical Services; Feces; Female; Fluid Therapy; Haiti; Humans; Length of Stay; Male; Organometallic Compounds; Probiotics; Saccharomyces; Salicylates; Severity of Illness Index; Treatment Outcome; Vibrio cholerae

2015

Other Studies

4 other study(ies) available for salicylates and Cholera

Article	Year
Testing for cholera antagonists. Lancet (London, England), 1977, Jan-01, Volume: 1, Issue:8001 Topics: Adult; Animals; Antitoxins; Cholera; Diarrhea; Dogs; Drug Evaluation, Preclinical; Humans; Indomethacin; Intestinal Secretions; Salicylates	1977
Letter: Biochemical treatment of cholera. Lancet (London, England), 1976, Apr-24, Volume: 1, Issue:7965 Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Antagonists; Cholera; Cyclic AMP; Diarrhea; Humans; Niridazole; Prostaglandin Antagonists; Salicylates	1976
Indomethacin in cholera diarrhoea. Lancet (London, England), 1976, Nov-06, Volume: 2, Issue:7993 Topics: Animals; Cholera; Dogs; Drug Evaluation; Humans; Indomethacin; Salicylates	1976
Studies on vaccination against cholera. VI. Toxicity of V. cholerae suspensions killed by various methods. Zeitschrift fur Immunitatsforschung, Allergie und klinische Immunologie, 1970, Volume: 139, Issue:3 Topics: Animals; Body Weight; Cholera; Cholera Vaccines; Formaldehyde; Hot Temperature; Lactones; Mercury; Mice; Phenols; Salicylates; Suspensions; Vaccination; Vibrio	1970