salicylates and Ascites

salicylates has been researched along with Ascites* in 4 studies

Reviews

1 review(s) available for salicylates and Ascites

Article	Year
[PERITONEAL DIALYSIS IN CLINICAL PRACTICE. (REVIEW OF THE LITERATURE)]. Sovetskaia meditsina, 1964, Volume: 27 Topics: Acute Kidney Injury; Ascites; Dialysis; Ethanol; Methanol; Nephritis; Peritoneal Cavity; Peritoneal Dialysis; Poisoning; Renal Dialysis; Renal Insufficiency; Salicylates; Toxicology	1964

Trials

1 trial(s) available for salicylates and Ascites

Article	Year
Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites. Journal of hepatology, 1993, Volume: 19, Issue:2 Imidazole-salicylate is a non-steroidal anti-inflammatory drug with limited inhibitory effects on prostaglandin synthesis. The renal effects of this drug were investigated by a double-blind cross-over study in 10 patients with cirrhosis and ascites. Two therapeutic doses of imidazole-salicylate (750 mg each) were given at midnight and 08:00 h and 80 mg of furosemide were injected intravenously at 09:00 h. The same procedure was followed on another day but a placebo replaced imidazole-salicylate. Renal function (creatinine clearance, free water and electrolyte excretions) and urinary excretion of prostaglandin E, 6-keto-prostaglandin F1 alpha and thromboxane B2 were evaluated for 8 h after the first dose of the drug and for 2 h after furosemide injection. Platelet thromboxane production was also determined 9 h after the first administration of drug or placebo. Imidazole-salicylate did not affect renal function or inhibit kidney prostanoid production either under basal conditions or after the stimulating effect of furosemide. On the contrary, imidazole-salicylate significantly inhibited platelet thromboxane production (45.8 +/- 9 vs. 69.4 +/- 7.5 ng/ml, P < 0.05). These results suggest that imidazole-salicylate is an anti-inflammatory drug that can be given to patients with decompensated cirrhosis without risk of inhibiting kidney prostaglandin synthesis or the renal response to furosemide. Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Blood Platelets; Diuretics; Double-Blind Method; Female; Furosemide; Glomerular Filtration Rate; Humans; Imidazoles; Kidney; Liver Cirrhosis; Male; Middle Aged; Prostaglandins F; Salicylates; Thromboxane B2; Time Factors	1993

Article

Year

Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites.

Journal of hepatology, 1993, Volume: 19, Issue:2

Imidazole-salicylate is a non-steroidal anti-inflammatory drug with limited inhibitory effects on prostaglandin synthesis. The renal effects of this drug were investigated by a double-blind cross-over study in 10 patients with cirrhosis and ascites. Two therapeutic doses of imidazole-salicylate (750 mg each) were given at midnight and 08:00 h and 80 mg of furosemide were injected intravenously at 09:00 h. The same procedure was followed on another day but a placebo replaced imidazole-salicylate. Renal function (creatinine clearance, free water and electrolyte excretions) and urinary excretion of prostaglandin E, 6-keto-prostaglandin F1 alpha and thromboxane B2 were evaluated for 8 h after the first dose of the drug and for 2 h after furosemide injection. Platelet thromboxane production was also determined 9 h after the first administration of drug or placebo. Imidazole-salicylate did not affect renal function or inhibit kidney prostanoid production either under basal conditions or after the stimulating effect of furosemide. On the contrary, imidazole-salicylate significantly inhibited platelet thromboxane production (45.8 +/- 9 vs. 69.4 +/- 7.5 ng/ml, P < 0.05). These results suggest that imidazole-salicylate is an anti-inflammatory drug that can be given to patients with decompensated cirrhosis without risk of inhibiting kidney prostaglandin synthesis or the renal response to furosemide.

Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Ascites; Blood Platelets; Diuretics; Double-Blind Method; Female; Furosemide; Glomerular Filtration Rate; Humans; Imidazoles; Kidney; Liver Cirrhosis; Male; Middle Aged; Prostaglandins F; Salicylates; Thromboxane B2; Time Factors

1993

Other Studies

2 other study(ies) available for salicylates and Ascites

Article	Year
HOST-TUMOUR RELATIONSHIP. XVII. QUANTITATIVE CHANGES IN SOME FRACTIONS OF SULPHOSALICYLIC ACID SOLUBLE SUBSTANCES IN THE SERUM AND ASCITES FLUID OF YOSHIDA ASCITES TUMOUR BEARING RATS. Neoplasma, 1964, Volume: 11 Topics: Ascites; Benzenesulfonates; Blood Proteins; Mucoproteins; Neoplasms; Neoplasms, Experimental; Rats; Research; Salicylates; Salicylic Acid	1964
[Further experiments on the possibility of preventing ascites in the stasis liver by means of creation of an adhesive perihepatitis]. Minerva chirurgica, 1963, May-31, Volume: 18 Topics: Adhesives; Ascites; Hepatitis; Humans; Liver Cirrhosis; Phenols; Salicylates; Tissue Adhesions	1963