salicylates and Arthritis--Reactive

Traveler's diarrhea (TD) is the most common travel-related illness, and it can have a significant impact on the traveler. Pretravel consultation provides an excellent opportunity for the clinician to counsel the traveler and discuss strategies such as food and water hygiene, vaccinations, and medications for prophylaxis or self-treatment that may decrease the incidence and impact of TD. Postinfectious sequelae, such as postinfectious irritable bowel syndrome, reactive arthritis, and Guillain-Barre syndrome, may develop weeks or months after return.

Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Antidiarrheals; Arthritis, Reactive; Bismuth; Dehydration; Diarrhea; Female; Fluid Therapy; Foodborne Diseases; Guillain-Barre Syndrome; Humans; Immunocompromised Host; Irritable Bowel Syndrome; Organometallic Compounds; Pregnancy; Probiotics; Risk Factors; Salicylates; Travel; Travel Medicine; Vaccines; Waterborne Diseases

Arthritis, following infection caused by group A beta-hemolytic streptococcus, is classically attributed to acute rheumatic fever. However, a new clinical syndrome, called poststreptococcal reactive arthritis, as a distinct entity from acute rheumatic fever, was described recently. The purpose of this paper is to provide a summary of published information on poststreptococcal reactive arthritis. The paper outlines its clinical description and proposed diagnostic criteria. Similarities and differences between poststreptococcal reactive arthritis and acute rheumatic fever are discussed. Information regarding long-term risk of carditis following poststreptococcal reactive arthritis is provided, and therapeutic recommendations are outlined.

Topics: Acute Disease; Adolescent; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Reactive; Child; Diagnosis, Differential; Humans; Rheumatic Fever; Risk Factors; Salicylates; Streptococcal Infections; Time Factors

Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Child; Humans; Rheumatic Fever; Salicylates; Streptococcal Infections; Streptococcus pyogenes

Topics: Antimetabolites; Arthritis, Reactive; Chlamydia; Chlamydia Infections; Dysentery, Bacillary; Female; Hepatitis B Antigens; Herpesviridae Infections; Humans; Indomethacin; Leukocyte Count; Male; Mycoplasma; Mycoplasma Infections; Phenylbutazone; Prognosis; Salicylates; Salmonella Infections; Sexually Transmitted Diseases; Shigella; Synovial Fluid

Poststreptococcal reactive arthritis (PSRA) is an acute, nonsuppurative arthritis following documented streptococcal infections. Although most authors accepted it as a different entity, the differences from acute rheumatic fever (ARF) are not clear. To document and compare the clinical and laboratory characteristics of PSRA and ARF, 24 patients with PSRA and 20 with ARF were enrolled in the study. The latency period from upper respiratory tract infection was shorter in patients with PSRA ( P<0.01). However, 25% of the patients with ARF had also short (<10 days) latency periods. Although symmetric and nonmigratory arthritis were more frequent in patients with PSRA, there was no significant difference for the distribution of mono-, oligo-, and polyarticular disease between PSRA and ARF patients. The frequency of small joint and hip involvement was also similar between the patient groups. Unresponsiveness of articular symptoms to salicylate therapy within 72 h was more frequent in patients with PSRA (P<0.001). However, in a substantial part of the patients with ARF (nine patients, 45%), joint symptoms also had no response during the first 72 h. Since there is a considerable overlap of symptoms, signs, and laboratory features of PSRA and ARF, a line between these two entities could not be easily drawn. We conclude that these two conditions are actually different presentations of the same disease.

Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Reactive; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Male; Rheumatic Fever; Salicylates; Streptococcal Infections; Streptococcus pyogenes; Time Factors

Topics: Arthritis, Reactive; Chemical and Drug Induced Liver Injury; Histocompatibility Antigens; HLA Antigens; Humans; Liver; Salicylates

Topics: Arthritis, Juvenile; Arthritis, Reactive; Arthritis, Rheumatoid; Chemotaxis; Exudates and Transudates; Humans; Joint Diseases; Leukocytes; Osteoarthritis; Phenylbutazone; Rheumatoid Factor; Salicylates; Synovial Fluid

Topics: Adult; Anthracenes; Antisepsis; Arthritis, Reactive; Coal Tar; Demeclocycline; Humans; Male; Phenylbutazone; Psoriasis; Salicylates

Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents; Antidepressive Agents; Arthritis, Reactive; Arthritis, Rheumatoid; Drug Synergism; Humans; Osteoarthritis; Rheumatic Diseases; Salicylates; Spondylitis, Ankylosing

Topics: Arthritis, Reactive; Humans; Salicylates; Spondylitis; Spondylitis, Ankylosing