salicortin and Neoplasms

salicortin has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for salicortin and Neoplasms

ArticleYear
Miyabeacin: A new cyclodimer presents a potential role for willow in cancer therapy.
    Scientific reports, 2020, 04-15, Volume: 10, Issue:1

    Willow (Salix spp.) is well known as a source of medicinal compounds, the most famous being salicin, the progenitor of aspirin. Here we describe the isolation, structure determination, and anti-cancer activity of a cyclodimeric salicinoid (miyabeacin) from S. miyabeana and S. dasyclados. We also show that the capability to produce such dimers is a heritable trait and how variation in structures of natural miyabeacin analogues is derived via cross-over Diels-Alder reactions from pools of ortho-quinol precursors. These transient ortho-quinols have a role in the, as yet uncharacterised, biosynthetic pathways around salicortin, the major salicinoid of many willow genotypes.

    Topics: Antineoplastic Agents, Phytogenic; Benzyl Alcohols; Biosynthetic Pathways; Cell Line, Tumor; Drug Screening Assays, Antitumor; Glucosides; Humans; Inhibitory Concentration 50; Neoplasms; Plant Bark; Salix

2020