saikosaponin d has been researched along with Disease Models, Animal in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 8 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, X; Du, Z; Fu, Q; Gao, S; Li, S; Liu, T; Ma, S; Ma, Y; Tang, R; Wang, W; Wang, X; Yu, J | 1 |
| Cui, L; Li, C; Xu, X; Yang, L; Zhang, L; Zhuo, Y | 1 |
| Ali, H; Ali, J; Islam, SU; Khan, AU; Khan, S; Kim, YS; Shah, FA | 1 |
| Chai, OH; Lee, EJ; Piao, CH; Song, CH | 1 |
| Gao, J; Guan, X; Guo, J; Liu, B; Liu, S; Qin, Z; Tang, K; Wang, X; Zhang, F | 1 |
| An, Y; Li, J; Li, M; Li, P; Ren, J; Wu, M; Xie, Y; Xiong, W; Xue, H; Yan, D; Zhong, G | 1 |
| Li, W; Liao, X; Liu, Y; Su, Y; Wang, Q; Xu, Y; Yu, Y; Zhang, J; Zhang, S; Zhao, M | 1 |
| Hu, MZ; Li, YB; Liu, B; Mi, LF; Wang, AR; Zhang, ZL; Zhao, ZY; Zheng, S | 1 |
| Chen, G; Fu, Y; Yao, L; Yao, T; Zhang, L; Zhou, C | 1 |
| Cho, S; Khan, A; Kim, YJ; Lee, S; Pan, JH; Park, YH | 1 |
| Bi, Y; Ding, L; Gao, W; Ye, M; Zhu, W | 1 |
| Du, ZA; Hu, ZS; Sun, MN | 1 |
| Cheng, H; Cheng, L; Song, S; Wang, L; Xu, D; Yin, Q; Zhang, M; Zhou, X | 1 |
| Cao, C; Ding, H; Liu, Y | 1 |
| Chen, J; Chen, W; Duan, M; Li, B; Li, Q; Liao, M; Ling, F; Liu, Y; Lu, C; Qi, W; Xiao, K; Zeng, Z; Zhao, Y | 1 |
| Huang, W; Sun, R | 1 |
| Huang, W; Huang, Y; Lv, L; Sun, R; Wang, R | 1 |
| Cheng, WJ; Cheng, XL; Chu, KD; Liu, JZ; Liu, QB; Pan, XD; Shi, YL; Tan, YH; Yu, KY; Zhang, MJ; Zheng, S | 1 |
18 other study(ies) available for saikosaponin d and Disease Models, Animal
| Article | Year |
|---|---|
Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress.
Topics: Animals; Calcium; Depression; Disease Models, Animal; Endoplasmic Reticulum Stress; Hippocampus; Lipopolysaccharides; Mice; Microglia; Neuroinflammatory Diseases; NF-kappa B; Signal Transduction; Stress, Psychological; Toll-Like Receptor 4 | 2023 |
Saikosaponin d modulates the polarization of tumor-associated macrophages by deactivating the PI3K/AKT/mTOR pathway in murine models of pancreatic cancer.
Topics: Animals; Carcinoma, Pancreatic Ductal; Disease Models, Animal; Mice; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Saponins; TOR Serine-Threonine Kinases; Tumor Microenvironment; Tumor-Associated Macrophages | 2023 |
Mucoprotective effects of Saikosaponin-A in 5-fluorouracil-induced intestinal mucositis in mice model.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Cytokines; Diarrhea; Disease Models, Animal; Fluorouracil; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred BALB C; Mucositis; Oleanolic Acid; Saponins | 2019 |
Saikosaponin A ameliorates nasal inflammation by suppressing IL-6/ROR-γt/STAT3/IL-17/NF-κB pathway in OVA-induced allergic rhinitis.
Topics: Animals; Cytokines; Disease Models, Animal; Immunoglobulin E; Immunoglobulin G; Inflammation; Interleukin-17; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Nasal Mucosa; NF-kappa B; Nuclear Receptor Subfamily 1, Group F, Member 3; Oleanolic Acid; Ovalbumin; Rhinitis, Allergic; Saponins; Signal Transduction; STAT3 Transcription Factor; Th17 Cells; Th2 Cells | 2020 |
Proteomics-based screening of the target proteins associated with antidepressant-like effect and mechanism of Saikosaponin A.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Dopamine; Male; Oleanolic Acid; Proteome; Rats; Rats, Sprague-Dawley; Saponins; Stress, Psychological | 2020 |
Saikosaponin-d ameliorates dextran sulfate sodium-induced colitis by suppressing NF-κB activation and modulating the gut microbiota in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colitis, Ulcerative; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Gastrointestinal Microbiome; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred BALB C; Mucins; NF-kappa B; Oleanolic Acid; Saponins; Signal Transduction | 2020 |
Active components of Bupleurum chinense and Angelica biserrata showed analgesic effects in formalin induced pain by acting on Nav1.7.
Topics: Analgesics; Angelica; Animals; Bupleurum; CHO Cells; Cricetulus; Disease Models, Animal; Drugs, Chinese Herbal; Female; Formaldehyde; Furocoumarins; Hot Temperature; Male; Medicine, Chinese Traditional; Mice; NAV1.7 Voltage-Gated Sodium Channel; Oleanolic Acid; Pain; Plant Roots; Saponins; Sodium | 2021 |
Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway.
Topics: Animals; Antidepressive Agents; Apoptosis; Behavior, Animal; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Depression; Disease Models, Animal; Hippocampus; Ischemic Stroke; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Recovery of Function; Saponins | 2021 |
Saikosaponin-d Alleviates Renal Inflammation and Cell Apoptosis in a Mouse Model of Sepsis via TCF7/FOSL1/Matrix Metalloproteinase 9 Inhibition.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Disease Models, Animal; Epithelial Cells; Hepatocyte Nuclear Factor 1-alpha; Humans; Inflammation; Kidney; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Nephritis; Oleanolic Acid; Proto-Oncogene Proteins c-fos; Saponins; Sepsis | 2021 |
Investigation of the Hepatoprotective Effect of Prunus mume Sieb. et Zucc Extract in a Mouse Model of Alcoholic Liver Injury Through High-Resolution Metabolomics.
Topics: Animals; Antioxidants; Chromatography, Liquid; Disease Models, Animal; Ethanol; Fatty Liver, Alcoholic; Humans; Liver; Male; Mass Spectrometry; Metabolomics; Mice; Mice, Inbred C57BL; Oleanolic Acid; Phosphatidylcholines; Prunus; Saponins | 2017 |
SSa ameliorates the Glu uptaking capacity of astrocytes in epilepsy via AP-1/miR-155/GLAST.
Topics: Animals; Astrocytes; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Transporter 1; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; MicroRNAs; Oleanolic Acid; Pentylenetetrazole; Proto-Oncogene Proteins c-fos; Rats, Wistar; Saponins; Transcription Factor AP-1 | 2017 |
Saikosaponin a Ameliorates LPS-Induced Acute Lung Injury in Mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Caspase 1; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Lung; Male; Mice, Inbred BALB C; Neutrophil Infiltration; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Pulmonary Edema; Saponins; Tumor Necrosis Factor-alpha | 2018 |
Attenuation of neuropathic pain by saikosaponin a in a rat model of chronic constriction injury.
Topics: Animals; Chronic Disease; Constriction; Disease Models, Animal; Male; Neuralgia; NF-kappa B; Oleanolic Acid; Rats, Sprague-Dawley; Saponins; Sciatic Nerve; Spinal Cord; Tumor Necrosis Factor-alpha | 2014 |
Pharmacological experimental study of the anti-depressant effect of total saikosaponins.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hindlimb Suspension; Humans; Male; Mice; Motor Activity; Oleanolic Acid; Saponins | 2014 |
Saikosaponin A inhibits influenza A virus replication and lung immunopathology.
Topics: Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoblotting; Influenza A virus; Influenza, Human; Lung; Mice; Mice, Inbred C57BL; Oleanolic Acid; Orthomyxoviridae Infections; Respiratory Tract Infections; Saponins; Virus Replication | 2015 |
[Study on hepatotoxicity on rats caused by crude extracts of total saikosaponins and correlation with oxidative damage mechanism].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Humans; Liver; Male; Malondialdehyde; Oleanolic Acid; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Saponins; Superoxide Dismutase | 2010 |
[Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins].
Topics: Animals; Antimetabolites; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Female; Liver; Male; Mitochondria, Liver; Oleanolic Acid; Organ Size; Rats; Saponins | 2011 |
[Aike mixture has good anti-inflammatory and analgesic effects on mice].
Topics: Animals; Chronic Disease; Disease Models, Animal; Drug Combinations; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Phytotherapy; Prostatitis; Saponins | 2007 |