saikosaponin d has been researched along with Acute Liver Injury, Drug-Induced in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 10 (66.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J; Ma, RX; Wang, YF; Yao, Y; Zou, B | 1 |
| Gao, ZH; Li, RF; Li, SQ; Li, YY; Liu, WY; Wang, HW; Wang, JG; You, M | 1 |
| Chen, CI; Chen, CY; Cheng, HY; Huang, HH; Kuo, SM; Shiu, LY | 1 |
| Li, S; Peng, S; Qiao, Y; Shen, C; Wang, S; Wu, Q; Yang, W; Yu, Y; Zhang, M; Zhang, Q; Zhang, Y | 1 |
| Chen, Y; Li, Y; Lin, L; Que, R; Shen, Y; Yan, N | 1 |
| Chen, X; Peng, X; Rao, X; Zheng, C; Zhu, Y | 1 |
| Gao, JJ; Han, LW; He, QX; Liu, KC; Tu, PF; Xia, Q; Zhang, SS; Zhang, Y | 1 |
| Fang, Z; Gonzalez, FJ; Guo, B; Jiang, C; Kim, JH; Krausz, KW; Liu, A; Sun, L; Tanaka, N; Yang, J | 1 |
| Du, GH; Li, ZY; Qin, XM; Sun, HM; Xing, J | 1 |
| Chen, L; Jin, H; Lu, Y; Shao, J; Wu, L; Zhang, F; Zheng, S | 1 |
| Chao, JC; Chu, CC; Lin, YH; Tsai, YH; Wu, SJ | 1 |
| Chang, CC; Chao, JC; Tam, KW; Tsai, YH; Wu, SJ | 1 |
| Huang, W; Huang, Y; Lv, L; Sun, R; Wang, R | 1 |
| Abe, H; Arichi, S; Odashima, S; Sakaguchi, M | 1 |
| Chuang, CH; Lin, CC; Liu, SY; Yen, MH | 1 |
15 other study(ies) available for saikosaponin d and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Endoplasmic reticulum stress regulates autophagic response that is involved in Saikosaponin a-induced liver cell damage.
Topics: Animals; Apoptosis; Autophagy; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum Stress; Mice | 2023 |
[Effects of saikosaponin b_2 on inflammation and energy metabolism in mice with acute liver injury induced by LPS/GalN].
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytokines; Energy Metabolism; Galactosamine; Inflammation; Lipopolysaccharides; Liver; Mice; NF-kappa B; Oleanolic Acid; Random Allocation; Saponins; Sirtuins | 2019 |
Reparative and toxicity-reducing effects of liposome-encapsulated saikosaponin in mice with liver fibrosis.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Compounding; Drug Liberation; Hepatic Stellate Cells; Humans; Inhibitory Concentration 50; Liposomes; Liver; Liver Cirrhosis, Experimental; Male; Mice, Inbred C57BL; Oleanolic Acid; Protective Agents; Saponins; Thioacetamide | 2020 |
Content decline of SERCA inhibitors saikosaponin a and d attenuates cardiotoxicity and hepatotoxicity of vinegar-baked Radix bupleuri.
Topics: Acetic Acid; Animals; Animals, Newborn; Apoptosis; Bupleurum; Cardiotoxicity; Cell Line; Cells, Cultured; Chemical and Drug Induced Liver Injury; Female; Hep G2 Cells; Hot Temperature; Humans; Male; Myocytes, Cardiac; Oleanolic Acid; Plant Preparations; Plant Roots; Rats, Sprague-Dawley; Saponins; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2017 |
Saikosaponin‑d alleviates carbon‑tetrachloride induced acute hepatocellular injury by inhibiting oxidative stress and NLRP3 inflammasome activation in the HL‑7702 cell line.
Topics: Apoptosis; Carbon Tetrachloride; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Cytokines; Inflammasomes; Inflammation Mediators; Liver; Malondialdehyde; NLR Family, Pyrin Domain-Containing 3 Protein; Oleanolic Acid; Oxidative Stress; Saponins | 2018 |
Saikosaponin a ameliorates lipopolysaccharide and d‑galactosamine-induced liver injury via activating LXRα.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Galactosamine; Hep G2 Cells; Humans; Interleukin-1beta; Lipopolysaccharides; Liver; Liver X Receptors; Malondialdehyde; Mice, Inbred C57BL; Oleanolic Acid; Peroxidase; Saponins; Tumor Necrosis Factor-alpha | 2019 |
[Study on liver protection and hepatotoxicity of saikosaponin a based on zebrafish model].
Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Liver, Alcoholic; Oleanolic Acid; Saponins; Zebrafish | 2019 |
Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antipyretics; Bupleurum; Chemical and Drug Induced Liver Injury; Cytokines; Down-Regulation; Drugs, Chinese Herbal; Humans; Inactivation, Metabolic; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oleanolic Acid; Oxidative Stress; Plants, Medicinal; PPAR alpha; RNA, Messenger; Saponins; Signal Transduction; STAT3 Transcription Factor | 2014 |
Chemical and biological comparison of raw and vinegar-baked Radix Bupleuri.
Topics: Acetic Acid; Animals; Bupleurum; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Female; Liver; Magnetic Resonance Spectroscopy; Male; Mice; Oleanolic Acid; Plant Extracts; Saponins | 2015 |
Activation of Fas death receptor pathway and Bid in hepatocytes is involved in saikosaponin D induction of hepatotoxicity.
Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Bupleurum; Caspase 8; Cell Line; Chemical and Drug Induced Liver Injury; fas Receptor; Hepatocytes; Humans; Male; MAP Kinase Signaling System; Mice; Mitochondria; Oleanolic Acid; Saponins; Signal Transduction | 2016 |
Curcumin or saikosaponin a improves hepatic antioxidant capacity and protects against CCl4-induced liver injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Lipids; Liver; Liver Diseases; Male; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Saponins; Superoxide Dismutase | 2008 |
Curcumin and saikosaponin a inhibit chemical-induced liver inflammation and fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents; Bupleurum; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Collagen; Curcuma; Curcumin; Cytokines; Dietary Supplements; Drug Therapy, Combination; Fibrosis; Hydroxyproline; Inflammation; Liver; Male; NF-kappa B; Oleanolic Acid; Phytotherapy; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Rhizome; Saponins; Transforming Growth Factor beta1 | 2010 |
[Research on mechanism of energy metabolism disorders of rat's hepatoxicity induced by saikosaponins].
Topics: Animals; Antimetabolites; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Female; Liver; Male; Mitochondria, Liver; Oleanolic Acid; Organ Size; Rats; Saponins | 2011 |
Protective effect of saikosaponin-d isolated from Bupleurum falcatum L. on CCl4-induced liver injury in the rat.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Lipid Peroxides; Male; Microsomes, Liver; Necrosis; Oleanolic Acid; Organ Size; Plants, Medicinal; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1982 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Drugs, Chinese Herbal; Liver; Liver Diseases; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1991 |