safrole has been researched along with Tongue Neoplasms in 1 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
Tongue Neoplasms: Tumors or cancer of the TONGUE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, FS | 1 |
| Huang, AC | 1 |
| Yang, JS | 1 |
| Yu, CS | 1 |
| Lu, CC | 1 |
| Chiang, JH | 1 |
| Chiu, CF | 1 |
| Chung, JG | 1 |
1 other study available for safrole and Tongue Neoplasms
| Article | Year |
|---|---|
Safrole induces cell death in human tongue squamous cancer SCC-4 cells through mitochondria-dependent caspase activation cascade apoptotic signaling pathways.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Caspase 3; Caspase 8; Caspase 9; Ce | 2012 |