Page last updated: 2024-11-04

safrole and Pain

safrole has been researched along with Pain in 1 studies

Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maia, RC1
Silva, LL1
Mazzeu, EF1
Fumian, MM1
de Rezende, CM1
Doriguetto, AC1
CorrĂȘa, RS1
Miranda, AL1
Barreiro, EJ1
Fraga, CA1

Other Studies

1 other study available for safrole and Pain

ArticleYear
Synthesis and analgesic profile of conformationally constrained N-acylhydrazone analogues: discovery of novel N-arylideneamino quinazolin-4(3H)-one compounds derived from natural safrole.
    Bioorganic & medicinal chemistry, 2009, Sep-15, Volume: 17, Issue:18

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Female; Humans; Hydrazones; Male; Mice; Pain; Platele

2009