safrole has been researched along with Neoplasms in 8 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 2 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Ge, D | 1 |
| Jing, Q | 1 |
| Zhao, W | 1 |
| Yue, H | 1 |
| Su, L | 1 |
| Zhao, J | 1 |
| Bode, AM | 1 |
| Dong, Z | 1 |
| HAGAN, EC | 1 |
| JENNER, PM | 1 |
| JONES, WI | 1 |
| FITZHUGH, OG | 1 |
| LONG, EL | 1 |
| BROUWER, JG | 1 |
| WEBB, WK | 1 |
| Fairweather, FA | 1 |
| Swann, CA | 1 |
| Miller, EC | 2 |
| Miller, JA | 2 |
4 reviews available for safrole and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Toxic phytochemicals and their potential risks for human cancer.
Topics: Amygdalin; Aristolochic Acids; Capsaicin; Cell Line, Tumor; Cycasin; Diet; Drug Screening Assays, An | 2015 |
Food additives and cancer.
Topics: Animals; Chemical Phenomena; Chemistry; Female; Food Additives; Food Coloring Agents; Furylfuramide; | 1981 |
Carcinogens occurring naturally in foods.
Topics: Aflatoxins; Animals; Carcinogens, Environmental; Cycasin; Ethionine; Food; Griseofulvin; Humans; Neo | 1976 |
4 other studies available for safrole and Neoplasms
| Article | Year |
|---|---|
Finding ATF4/p75NTR/IL-8 signal pathway in endothelial-mesenchymal transition by safrole oxide.
Topics: Activating Transcription Factor 4; Fibrosis; Gene Expression Regulation; Gene Knockdown Techniques; | 2014 |
Safrole.
Topics: Animals; Carcinogens; Flavoring Agents; Humans; Neoplasms; Safrole | 2011 |
TOXIC PROPERTIES OF COMPOUNDS RELATED TO SAFROLE.
Topics: Animals; Carcinogens; Dogs; Esophageal Neoplasms; Guinea Pigs; Liver Neoplasms; Mice; Neoplasms; Neo | 1965 |
Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules.
Topics: 2-Acetylaminofluorene; Aflatoxins; Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; C | 1981 |