safrole has been researched along with Chemical Dependence in 3 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 19-year-old man developed a schizophrenia-like psychosis after ingesting isosafrole." | 7.67 | Isosafrole and schizophrenia-like psychosis. ( Haier, RJ; Keitner, GI; Sabaawi, M, 1984) |
| "A 19-year-old man developed a schizophrenia-like psychosis after ingesting isosafrole." | 3.67 | Isosafrole and schizophrenia-like psychosis. ( Haier, RJ; Keitner, GI; Sabaawi, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Manier, SK | 1 |
| Wagmann, L | 1 |
| Weber, AA | 1 |
| Meyer, MR | 1 |
| Beyer, J | 1 |
| Ehlers, D | 1 |
| Maurer, HH | 1 |
| Keitner, GI | 1 |
| Sabaawi, M | 1 |
| Haier, RJ | 1 |
3 other studies available for safrole and Chemical Dependence
| Article | Year |
|---|---|
Abuse of nutmeg seeds: Detectable by means of liquid chromatography-mass spectrometry techniques?
Topics: Allylbenzene Derivatives; Chromatography, Liquid; Dioxolanes; Gas Chromatography-Mass Spectrometry; | 2021 |
Abuse of nutmeg (Myristica fragrans Houtt.): studies on the metabolism and the toxicologic detection of its ingredients elemicin, myristicin, and safrole in rat and human urine using gas chromatography/mass spectrometry.
Topics: Allylbenzene Derivatives; Animals; Benzyl Compounds; Dioxolanes; Drug Monitoring; Gas Chromatography | 2006 |
Isosafrole and schizophrenia-like psychosis.
Topics: Adult; Amphetamine; Dioxoles; Humans; Lysergic Acid Diethylamide; Male; Psychoses, Substance-Induced | 1984 |