safrole has been researched along with Body Weight in 4 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The validity of the method was demonstrated by a linear dose-response relationship observed in rats given oral doses of safrole at 30, 75, and 150 mg/kg body weight." | 1.31 | Biological monitoring of environment exposure to safrole and the Taiwanese betel quid chewing. ( Chang, MJ; Hsieh, LL; Ko, CY; Lin, RF, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, MJ | 1 |
| Ko, CY | 1 |
| Lin, RF | 1 |
| Hsieh, LL | 1 |
| Lipsky, MM | 1 |
| Hinton, DE | 1 |
| Klaunig, JE | 1 |
| Trump, BF | 1 |
| Horbach, GJ | 1 |
| Venkatraman, JT | 1 |
| Fernandes, G | 1 |
| Taylor, G | 1 |
| Houston, JB | 1 |
| Elcombe, CR | 1 |
4 other studies available for safrole and Body Weight
| Article | Year |
|---|---|
Biological monitoring of environment exposure to safrole and the Taiwanese betel quid chewing.
Topics: Administration, Oral; Adolescent; Adult; Animals; Body Weight; Chromatography, High Pressure Liquid; | 2002 |
Biology of hepatocellular neoplasia in the mouse. I. Histogenesis of safrole-induced hepatocellular carcinoma.
Topics: Adenoma; Animals; Body Weight; Dioxoles; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inb | 1981 |
Food restriction prevents the loss of isosafrole inducible cytochrome P-450 mRNA and enzyme levels in aging rats.
Topics: Aging; Animals; Blotting, Western; Body Weight; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Ind | 1990 |
Effect of promethazine and isosafrole on rat-hepatic microsomal mono-oxygenase activity: comparison with classic inducers phenobarbitone and beta-naphthoflavone.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Body Weight; Dioxoles; Enzyme Induction; Flavonoids; Ma | 1985 |