safrole has been researched along with Bacteremia in 1 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grillo, S | 1 |
| Cuervo, G | 1 |
| Carratala, J | 1 |
| San-Juan, R | 1 |
| Aguado, JM | 1 |
| Morata, L | 1 |
| Gomez-Zorrilla, S | 1 |
| López-Contreras, J | 1 |
| Gasch, O | 1 |
| Gomila-Grange, A | 1 |
| Iftimie, S | 1 |
| Garcia-Pardo, G | 1 |
| Calbo, E | 1 |
| Boix-Palop, L | 1 |
| Oriol, I | 1 |
| Jover-Sáenz, A | 1 |
| López-Cortés, LE | 1 |
| Euba, G | 1 |
| Aguirregabiria, M | 1 |
| Garcia-Pais, MJ | 1 |
| Gioia, F | 1 |
| Paño, JR | 1 |
| Pedro-Botet, ML | 1 |
| Benítez, RM | 1 |
| Pérez-Rodríguez, MT | 1 |
| Meije, Y | 1 |
| Loeches-Yagüe, MB | 1 |
| Horna, G | 1 |
| Berbel, D | 1 |
| Domínguez, MÁ | 1 |
| Padullés, A | 1 |
| Cobo, S | 1 |
| Hereu, P | 1 |
| Videla, S | 1 |
| Tebe, C | 1 |
| Pallarés, N | 1 |
| Miro, JM | 1 |
| Pujol, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter, Randomised, Open-label Phase III-IV Study to Evaluate the Efficacy of Cloxacillin and Fosfomycin Combination Versus Cloxacillin Monotherapy in Patients With Methicillin-susceptible Staphylococcus Aureus Bacteraemia: SAFO Trial[NCT03959345] | Phase 4 | 215 participants (Actual) | Interventional | 2019-05-31 | Terminated (stopped due to Data safety and monitoring board(DSMB) have been performed when half of sample size (SS)have been reached. Recruitment was slower than expected so SS was recalculated. After analysis of data, DSMB recommended to stop study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for safrole and Bacteremia
| Article | Year |
|---|---|
Multicentre, randomised, open-label, phase IV-III study to evaluate the efficacy of cloxacillin plus fosfomycin versus cloxacillin alone in adult patients with methicillin-susceptible
Topics: Adult; Bacteremia; Cloxacillin; Fosfomycin; Humans; Methicillin; Multicenter Studies as Topic; Rando | 2021 |