safrole has been researched along with Aging in 4 studies
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).
safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ronis, MJ | 1 |
| Rowlands, JC | 1 |
| Hakkak, R | 1 |
| Badger, TM | 1 |
| Horbach, GJ | 3 |
| Van Asten, JG | 2 |
| Rietjens, IM | 1 |
| Kremers, P | 1 |
| Van Bezooijen, CF | 2 |
| Venkatraman, JT | 1 |
| Fernandes, G | 1 |
4 other studies available for safrole and Aging
| Article | Year |
|---|---|
Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood.
Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Caseins; Cytochrome P-450 CYP1A1; Cytochrome | 2001 |
The effect of age on inducibility of various types of rat liver cytochrome P-450.
Topics: Aging; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme-Li | 1992 |
Food restriction prevents the loss of isosafrole inducible cytochrome P-450 mRNA and enzyme levels in aging rats.
Topics: Aging; Animals; Blotting, Western; Body Weight; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Ind | 1990 |
The influence of ageing on the induction of the mRNAs of rat liver cytochromes P450IIB1 and P450IIB2.
Topics: Aging; Animals; Base Sequence; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Liver; Ma | 1990 |