Page last updated: 2024-08-24

safranal and Disease Models, Animal

safranal has been researched along with Disease Models, Animal in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Chen, W; Lin, Z; Teng, C; Wang, J; Wang, L; Wu, J; Wu, L; Zhang, Z1
Abd El-Salam, DM; Hussein, RM; Rizk, SM; Shehata, NI1
Chu, X; Guan, S; Jin, W; Wang, H; Xue, Y; Zhang, J; Zhang, Y1
Fu, W; Lertnimitphun, P; Lu, Y; Pei, W; Xu, H; Yang, B; Yuan, M; Zhang, W; Zhang, X; Zheng, C; Zhou, H1
Xi, G; Zhao, Y1
Eghdami, K; Erfanparast, A; Farshid, AA; Samadi, F; Tamaddonfard, E1
Bukhari, SI; Dhar, MK; Kaul, S; Pattnaik, B; Rayees, S1
Broadhead, GK; Chang, A; Grigg, J; McCluskey, P1
Dang, X; Fan, L; Ma, J; Song, J; Wang, K; Zhang, C; Zou, Y1
Cortez, MA; Hosseinzadeh, H; Liu, D; Sadeghnia, HR; Snead, OC1
Amin, B; Hosseinzadeh, H1
Cuenca, N; Esquiva, G; Fernández-Sánchez, L; Lax, P; Martín-Nieto, J; Pinilla, I1

Reviews

1 review(s) available for safranal and Disease Models, Animal

ArticleYear
Efficacy and Safety of Saffron Supplementation: Current Clinical Findings.
    Critical reviews in food science and nutrition, 2016, Dec-09, Volume: 56, Issue:16

    Topics: Affect; Animals; Antioxidants; Cardiovascular System; Carotenoids; Clinical Trials as Topic; Cognition; Crocus; Cyclohexenes; Disease Models, Animal; Humans; Oxidative Stress; Phytotherapy; Plant Preparations; Reproduction; Terpenes; Vision, Ocular; Vitamin A; Zeaxanthins

2016

Other Studies

11 other study(ies) available for safranal and Disease Models, Animal

ArticleYear
Safranal Treatment Induces Sirt1 Expression and Inhibits Endoplasmic Reticulum Stress in Mouse Chondrocytes and Alleviates Osteoarthritis Progression in a Mouse Model.
    Journal of agricultural and food chemistry, 2022, Aug-10, Volume: 70, Issue:31

    Topics: Animals; Apoptosis; Chondrocytes; Cyclohexenes; Disease Models, Animal; Endoplasmic Reticulum Stress; Mice; Osteoarthritis; Sirtuin 1; Terpenes; tert-Butylhydroperoxide

2022
Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington's disease.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Corpus Striatum; Disease Models, Animal; Huntington Disease; Motor Activity; Neuroprotective Agents; Nitro Compounds; Propionates; Rats; Rats, Wistar

2023
Safranal, an active constituent of saffron, ameliorates myocardial ischemia via reduction of oxidative stress and regulation of Ca
    Journal of pharmacological sciences, 2020, Volume: 143, Issue:3

    Topics: Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Crocus; Cyclohexenes; Disease Models, Animal; Isoproterenol; Male; Malondialdehyde; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxidative Stress; Phytotherapy; Rats, Sprague-Dawley; Superoxide Dismutase; Terpenes

2020
Safranal Alleviated OVA-Induced Asthma Model and Inhibits Mast Cell Activation.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Allergens; Animals; Anti-Inflammatory Agents; Asthma; Cell Degranulation; Cyclohexenes; Cytokines; Disease Models, Animal; Disease Susceptibility; Female; Immunoglobulin E; Inflammation Mediators; Mast Cells; Mice; NF-kappa B; Ovalbumin; Signal Transduction; Terpenes

2021
Safranal-promoted differentiation and survival of dopaminergic neurons in an animal model of Parkinson's disease.
    Pharmaceutical biology, 2018, Volume: 56, Issue:1

    Topics: Animals; Cell Differentiation; Cyclohexenes; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Green Fluorescent Proteins; Neural Stem Cells; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Terpenes; Tyrosine 3-Monooxygenase

2018
Comparison of the effects of crocin, safranal and diclofenac on local inflammation and inflammatory pain responses induced by carrageenan in rats.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carotenoids; Carrageenan; Cyclohexenes; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Hyperalgesia; Inflammation; Male; Neutrophil Infiltration; Pain; Pain Threshold; Rats; Rats, Wistar; Terpenes; Time Factors

2013
Safranal of Crocus sativus L. inhibits inducible nitric oxide synthase and attenuates asthma in a mouse model of asthma.
    Phytotherapy research : PTR, 2015, Volume: 29, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Cells, Cultured; Crocus; Cyclohexenes; Cytochromes c; Cytokines; Disease Models, Animal; Humans; Lung; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Plant Extracts; Terpenes

2015
Neuroprotective effects of safranal in a rat model of traumatic injury to the spinal cord by anti-apoptotic, anti-inflammatory and edema-attenuating.
    Tissue & cell, 2015, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; Cyclohexenes; Disease Models, Animal; Edema; Humans; Inflammation; Interleukin-10; Male; Neurons; Neuroprotective Agents; Rats; Spinal Cord Injuries; Terpenes; Tumor Necrosis Factor-alpha

2015
Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Volume: 11, Issue:3

    Topics: Animals; Autoradiography; Binding Sites; Brain; Crocus; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Absence; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Receptors, GABA-A; Terpenes

2008
Evaluation of aqueous and ethanolic extracts of saffron, Crocus sativus L., and its constituents, safranal and crocin in allodynia and hyperalgesia induced by chronic constriction injury model of neuropathic pain in rats.
    Fitoterapia, 2012, Volume: 83, Issue:5

    Topics: Acetone; Amines; Analgesics; Animals; Behavior, Animal; Carotenoids; Constriction; Crocus; Cyclohexanecarboxylic Acids; Cyclohexenes; Disease Models, Animal; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Neuralgia; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Terpenes; Walking

2012
Safranal, a saffron constituent, attenuates retinal degeneration in P23H rats.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Animals; Cell Communication; Crocus; Cyclohexenes; Disease Models, Animal; Neuroprotective Agents; Photoreceptor Cells; Rats; Retina; Retinal Bipolar Cells; Retinal Degeneration; Retinal Horizontal Cells; Retinitis Pigmentosa; Synaptic Transmission; Terpenes

2012