safingol and Liver Diseases

safingol has been researched along with Liver Diseases in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riley, RT; Sharma, RP; Suzuki, H1
Allgood, JC; Dillehay, DL; Merrill, AH; Moody, SJ; Morales, PR; Pallas, DC; Pruett, S; Symolon, H1
Carfagna, MA; Susick, RL; Young, KM1

Other Studies

3 other study(ies) available for safingol and Liver Diseases

ArticleYear
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase.
    Toxicology, 2007, Jan-05, Volume: 229, Issue:1-2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens, Environmental; Cell Proliferation; Chemical and Drug Induced Liver Injury; Fumonisins; Hepatocytes; In Situ Nick-End Labeling; Interferon-gamma; Interleukin-12; Liver Diseases; Liver Regeneration; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphotransferases (Alcohol Group Acceptor); RNA, Messenger; Sphingosine; Tumor Necrosis Factor-alpha; Weight Loss

2007
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:3

    Topics: Acylation; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; BALB 3T3 Cells; Biotransformation; Body Weight; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Kidney Diseases; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Transgenic; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Tissue Distribution

2007
Sex differences in rat hepatic cytolethality of the protein kinase C inhibitor safingol: role of biotransformation.
    Toxicology and applied pharmacology, 1996, Volume: 137, Issue:2

    Topics: Administration, Oral; Animals; Biotransformation; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; DNA; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Liver; Liver Diseases; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Sex Factors; Skin; Sphingosine; Time Factors

1996