safingol has been researched along with Liver Diseases in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riley, RT; Sharma, RP; Suzuki, H | 1 |
| Allgood, JC; Dillehay, DL; Merrill, AH; Moody, SJ; Morales, PR; Pallas, DC; Pruett, S; Symolon, H | 1 |
| Carfagna, MA; Susick, RL; Young, KM | 1 |
3 other study(ies) available for safingol and Liver Diseases
| Article | Year |
|---|---|
Inducible nitric oxide has protective effect on fumonisin B1 hepatotoxicity in mice via modulation of sphingosine kinase.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens, Environmental; Cell Proliferation; Chemical and Drug Induced Liver Injury; Fumonisins; Hepatocytes; In Situ Nick-End Labeling; Interferon-gamma; Interleukin-12; Liver Diseases; Liver Regeneration; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphotransferases (Alcohol Group Acceptor); RNA, Messenger; Sphingosine; Tumor Necrosis Factor-alpha; Weight Loss | 2007 |
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.
Topics: Acylation; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; BALB 3T3 Cells; Biotransformation; Body Weight; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Kidney Diseases; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Transgenic; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Tissue Distribution | 2007 |
Sex differences in rat hepatic cytolethality of the protein kinase C inhibitor safingol: role of biotransformation.
Topics: Administration, Oral; Animals; Biotransformation; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; DNA; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Liver; Liver Diseases; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Sex Factors; Skin; Sphingosine; Time Factors | 1996 |