safingol and Disease Models, Animal

safingol has been researched along with Disease Models, Animal in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (14.29)	18.2507
2000's	3 (21.43)	29.6817
2010's	6 (42.86)	24.3611
2020's	3 (21.43)	2.80

Authors

Authors	Studies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Avraham, R; Israely, T; Melamed, S; Politi, B; Vitner, EB	1
Allikmets, R; Badur, MG; Bahlo, M; Baldini, M; Bernstein, PS; Bonelli, R; Cai, C; Dorrell, MI; Eade, K; Egan, C; Eichler, F; Fallon, R; Friedlander, M; Fruttiger, M; Gantner, ML; Giles, S; Gillies, M; Guymer, R; Handzlik, MK; Harkins-Perry, S; Hart, BJ; Heeren, TFC; Ideguchi, Y; Kitano, M; Metallo, CM; Nagasaki, T; Okada, M; Sauer, L; Scheppke, L; Trombley, J; Wallace, M; Woods, SM	1
Funao, H; Ishihama, H; Ishii, K; Isogai, N; Kuramoto, T; Matsumoto, M; Nakamura, M; Shiono, Y; Yoshioka, K	1
Chen, Y; Ding, L; Dong, P; Jiang, M; Shi, H; Wen, S; Yang, J; Yang, Y; Zhu, Y	1
Chabowski, A; Konończuk, T; Kurek, K; Mikłosz, A; Żendzian-Piotrowska, M; Łukaszuk, B	1
Adeli, K; Baker, C; Dekker, MJ; Naples, M; Qiu, W; Sacco, J; Samsoondar, J; Zhang, R	1
Chabowski, A; Górski, J; Kurek, K; Mikłosz, A; Żendzian-Piotrowska, M; Łukaszuk, B	1
de Jongste, JC; Joza, S; Post, M; Reiss, I; Tibboel, J	1
Li, W; Norred, WP; Riley, RT; Voss, KA	1
Allgood, JC; Dillehay, DL; Merrill, AH; Moody, SJ; Morales, PR; Pallas, DC; Pruett, S; Symolon, H	1
Borracci, P; Cagiano, R; Carratù, MR; Cuomo, V; Tattoli, M; Trabace, L	1
Brady, RO; Goldin, E; Miller, SP; Pentchev, PG; Rodriguez-Lafrasse, C; Roff, CF; Vanier, MT	1
Brady, RO; Brown, A; Comly, ME; Cooney, A; Goldin, E; Miller, SP; Pentchev, PG; Roff, CF; Vanier, MT	1

Reviews

1 review(s) available for safingol and Disease Models, Animal

Article	Year
Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport. Developmental neuroscience, 1991, Volume: 13, Issue:4-5 Topics: Amines; Androstenes; Animals; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Fibroblasts; Filipin; Humans; Imipramine; Lysosomes; Mice; Morpholines; Niemann-Pick Diseases; Sphingosine; Structure-Activity Relationship	1991

Article

Year

Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport.

Developmental neuroscience, 1991, Volume: 13, Issue:4-5

Topics: Amines; Androstenes; Animals; Biological Transport; Cells, Cultured; Cholesterol; Cholesterol Esters; Disease Models, Animal; Fibroblasts; Filipin; Humans; Imipramine; Lysosomes; Mice; Morpholines; Niemann-Pick Diseases; Sphingosine; Structure-Activity Relationship

1991

Other Studies

13 other study(ies) available for safingol and Disease Models, Animal

Article	Year
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Elevation in sphingolipid upon SARS-CoV-2 infection: possible implications for COVID-19 pathology. Life science alliance, 2022, Volume: 5, Issue:1 Topics: Animals; Chlorocebus aethiops; Chromatography, Liquid; COVID-19; Dioxanes; Disease Models, Animal; Gangliosides; Glucosyltransferases; Humans; Mass Spectrometry; Mice, Transgenic; Pyrrolidines; SARS-CoV-2; Sphingolipids; Sphingosine; Vero Cells; Virus Replication	2022
Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. The New England journal of medicine, 2019, 10-10, Volume: 381, Issue:15 Topics: Adult; Aged; Animals; Disease Models, Animal; DNA Mutational Analysis; Exome; Female; Hereditary Sensory and Autonomic Neuropathies; Humans; Lipid Metabolism; Macula Lutea; Male; Mice; Middle Aged; Mutation; Pedigree; Retinal Telangiectasis; Risk Factors; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Young Adult	2019
Potential osteomyelitis biomarkers identified by plasma metabolome analysis in mice. Scientific reports, 2020, 01-21, Volume: 10, Issue:1 Topics: Animals; Biomarkers; Carnitine; Citric Acid Cycle; Disease Models, Animal; Fatty Acids; Ketoglutaric Acids; Luminescent Measurements; Male; Metabolome; Mice, Inbred BALB C; Osteomyelitis; Sphingolipids; Sphingosine; Staphylococcal Infections; Staphylococcus aureus; Succinic Acid; Surgical Wound Infection	2020
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE Atherosclerosis, 2017, Volume: 262 Topics: Animals; Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Diet, High-Fat; Discriminant Analysis; Disease Models, Animal; Disease Progression; Dyslipidemias; Genetic Predisposition to Disease; Lipids; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Mice, Knockout, ApoE; Pattern Recognition, Automated; Phenotype; Phosphatidylcholines; Plaque, Atherosclerotic; Sphingomyelins; Sphingosine	2017
Cerulein-Induced Acute Pancreatitis Affects Sphingomyelin Signaling Pathway in Rats. Pancreas, 2018, Volume: 47, Issue:7 Topics: Acute Disease; Animals; Ceramides; Ceruletide; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Disease Models, Animal; Humans; Pancreas; Pancreatitis; Rats, Wistar; Signal Transduction; Sphingomyelins; Sphingosine	2018
Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis, 2013, Volume: 228, Issue:1 Topics: Animal Feed; Animals; Apolipoprotein B-100; Cricetinae; Dietary Fats; Disease Models, Animal; Dyslipidemias; Fatty Acids, Monounsaturated; Fructose; Glucose Intolerance; Hepatitis; Immunosuppressive Agents; Insulin Resistance; Lipoproteins, VLDL; Liver; Male; Mesocricetus; Signal Transduction; Sphingolipids; Sphingosine	2013
Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance. Journal of diabetes research, 2015, Volume: 2015 Topics: Animals; Ceramides; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Fatty Acids, Monounsaturated; Glycolysis; Insulin Resistance; Lysophospholipids; Male; Muscle, Skeletal; Oxygen; Rats; Rats, Wistar; Signal Transduction; Sphingolipids; Sphingosine	2015
Amelioration of hyperoxia-induced lung injury using a sphingolipid-based intervention. The European respiratory journal, 2013, Volume: 42, Issue:3 Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage Fluid; Bronchopulmonary Dysplasia; Ceramides; Chromatography, Liquid; Disease Models, Animal; Hyperoxia; Lung; Lung Injury; Mass Spectrometry; Mice; Mice, Inbred C57BL; Oxygen Inhalation Therapy; Sphingolipids; Sphingosine; Vital Capacity	2013
Role of proliferation in the toxicity of fumonisin B1: enhanced hepatotoxic response in the partially hepatectomized rat. Journal of toxicology and environmental health. Part A, 2000, Aug-11, Volume: 60, Issue:7 Topics: Animals; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Fumonisins; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mycotoxins; Rats; Rats, Sprague-Dawley; Sphingosine; Time Factors	2000
Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation. Drug and chemical toxicology, 2007, Volume: 30, Issue:3 Topics: Acylation; Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; BALB 3T3 Cells; Biotransformation; Body Weight; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Kidney Diseases; Liver; Liver Diseases; Male; Methylation; Mice; Mice, Transgenic; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sphingosine; Tissue Distribution	2007
Prenatal exposure model simulating CO inhalation in human cigarette smokers: sphingomyelin alterations in the rat sciatic nerve. Toxicology letters, 2000, Sep-30, Volume: 117, Issue:1-2 Topics: Administration, Inhalation; Air Pollutants; Animals; Brain; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Female; Humans; Male; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sciatic Nerve; Sphingomyelins; Sphingosine; Tobacco Smoke Pollution	2000
Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver. Biochimica et biophysica acta, 1992, Aug-19, Volume: 1127, Issue:3 Topics: Animals; Cholesterol; Chromatography, Thin Layer; Cytosol; Disease Models, Animal; Kinetics; Liver; Lysosomes; Mass Spectrometry; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Niemann-Pick Diseases; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Species Specificity; Sphingosine	1992