safingol has been researched along with Acute Promyelocytic Leukemia in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 9 (75.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hazel, BA; Kalf, GF; Niculescu, R; O'Connor, A | 1 |
| Abita, JP; Chedeville, A; Gespach, C; Zimber, A | 1 |
| Hsiao, TF; Hui, EK; Wei, LL; Yung, BY | 1 |
| Hui, EK; Yung, BY | 2 |
| Hui, EK; Tzeng, WF; Wei, JS; Wei, LL; Yung, BY | 1 |
| Alkan, S; Amin, HM; Denning, MF; Ergin, M; Quevedo, ME | 1 |
| Hui, EK; Luo, KJ; Yung, BY | 1 |
| Hui, EK; Wei, JS; Wei, LL; Yung, BY | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Stevens, VL; Winton, EF | 1 |
| Hsu, T; Simpson, RU; Taylor, JM; Wendt, MD | 1 |
| Kinkade, JM; Merrill, AH; Owens, NE; Smith, EE; Stevens, VL; Winton, EF | 1 |
12 other study(ies) available for safingol and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
Benzene and its metabolite, hydroquinone, induce granulocytic differentiation in myeloblasts by interacting with cellular signaling pathways activated by granulocyte colony-stimulating factor.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzene; Cell Differentiation; Cell Division; Cell Line; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Humans; Hydroquinones; Interleukin-3; Leukemia, Promyelocytic, Acute; Leukotriene Antagonists; Leukotriene D4; Lipoxygenase Inhibitors; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Protein Kinase C; Receptors, Leukotriene; Signal Transduction; Sphingosine; Tumor Cells, Cultured | 1995 |
Inhibition of proliferation and induction of monocytic differentiation on HL60 human promyelocytic leukemia cells treated with bile acids in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bile Acids and Salts; Cell Cycle; Cell Differentiation; Cell Division; Chenodeoxycholic Acid; Deoxycholic Acid; Flow Cytometry; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Lithocholic Acid; Monocytes; Piperazines; Protein Kinase C; Sphingosine; Tretinoin; Tumor Cells, Cultured | 1994 |
Sphinganine potentiation of dimethyl sulfoxide-induced granulocyte differentiation, increase of alkaline phosphatase activity and decrease of protein kinase C activity in a human leukemia cell line (HL-60).
Topics: Alkaline Phosphatase; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Drug Synergism; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Kinase C; Sphingosine; Time Factors; Tumor Cells, Cultured | 1994 |
Differential regulation of protein kinase C isoenzymes during sphinganine potentiation of retinoic acid-induced granulocytic differentiation in human leukemia HL-60 cells.
Topics: Blotting, Western; Cell Differentiation; Cell Line; Diglycerides; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Granulocytes; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Protein Kinase C; Sphingosine; Tretinoin; Tumor Cells, Cultured | 1993 |
Alkaline phosphatase activity during sphinganine potentiation of retinoic acid-induced differentiation of human promyelocytic leukemia cell line, HL-60.
Topics: Alkaline Phosphatase; Cell Differentiation; Cell Line; Drug Synergism; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Sphingosine; Time Factors; Tretinoin; Tumor Cells, Cultured | 1993 |
Characterization of apoptosis induced by protein kinase C inhibitors and its modulation by the caspase pathway in acute promyelocytic leukaemia.
Topics: Apoptosis; Carbazoles; Caspases; Cell Line; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Genistein; Humans; Indoles; Leukemia, Promyelocytic, Acute; Protein Kinase C; Sphingosine | 2000 |
Interaction of antileukemia agents adriamycin and daunomycin with sphinganine on the differentiation of human leukemia cell line HL-60.
Topics: Cell Differentiation; Daunorubicin; Doxorubicin; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Protein Kinase C; Sphingosine; Tumor Cells, Cultured | 1992 |
Protein kinase C activity during sphinganine potentiation of retinoic acid-induced differentiation in a human leukemia cell line (HL-60).
Topics: Cell Differentiation; Cell Division; Cell Line; Drug Synergism; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; Sphingosine; Tretinoin; Tumor Cells, Cultured | 1992 |
Alkaline phosphatase activity during differentiation of the human promyelocytic leukemia cell line, HL-60.
Topics: Alkaline Phosphatase; Cell Differentiation; Cell Line; Enzyme Induction; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Sphingosine; Tretinoin | 1992 |
Modulation of retinoic acid-induced differentiation of human leukemia (HL-60) cells by serum factors and sphinganine.
Topics: Blood Physiological Phenomena; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
1,25-Dihydroxyvitamin D3 regulation of c-myc protooncogene transcription. Possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcitriol; Cell Differentiation; Cell Line; Cell Nucleus; Ethanol; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Sphingosine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Differential effects of long-chain (sphingoid) bases on the monocytic differentiation of human leukemia (HL-60) cells induced by phorbol esters, 1 alpha, 25-dihydroxyvitamin D3, or ganglioside GM3.
Topics: Antigens, Neoplasm; Antigens, Surface; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Survival; G(M3) Ganglioside; Gangliosides; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |