saccharin has been researched along with Urinary Calculi in 5 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In contrast, nongenotoxic chemicals, such as chemicals causing urinary calculi or sodium saccharin and related sodium and potassium salts, frequently are carcinogenic only at high doses and/or only in specific species." | 4.79 | Human relevance of animal carcinogenicity studies. ( Cohen, SM, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmähl, D | 1 |
| Habs, M | 1 |
| Hicks, RM | 3 |
| Cohen, SM | 1 |
| Chowaniec, J | 1 |
| Chowaniec, AJ | 1 |
| Wakefield, JS | 1 |
2 reviews available for saccharin and Urinary Calculi
| Article | Year |
|---|---|
Promotion in bladder cancer.
Topics: Animals; Carcinogens; Cocarcinogenesis; Cyclamates; Cyclophosphamide; Humans; Hyperplasia; Mice; Neo | 1982 |
Human relevance of animal carcinogenicity studies.
Topics: 2-Acetylaminofluorene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Disease Models, Animal; FAN | 1995 |
3 other studies available for saccharin and Urinary Calculi
| Article | Year |
|---|---|
Investigations on the carcinogenicity of the artificial sweeteners sodium cyclamate and sodium saccharin in rats in a two-generation experiment.
Topics: Animals; Carcinogens; Cyclamates; Female; Male; Rats; Rats, Inbred Strains; Saccharin; Sucrose; Swee | 1984 |
Response of the rat to saccharin with particular reference to the urinary bladder.
Topics: Animals; Body Weight; Drug Administration Schedule; Female; Hydrogen-Ion Concentration; Male; Rats; | 1979 |
Proceedings: Histology of tumour formation in the bladder of rats receiving dietary saccharin and a single dose of N-methyl N-nitrosourea.
Topics: Animals; Diet; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Saccharin; Urinary Bladder Neop | 1974 |