saccharin and Ulcer
saccharin has been researched along with Ulcer in 4 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ulceration of the bladder, induced by cyclophosphamide (CP) or freezing, followed by sodium saccharin in the diet results in the induction of bladder cancer." | 7.67 | Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin. ( Cohen, SM; Hasegawa, R; Murasaki, G; Suzuki, T, 1984) |
| "Sodium saccharin was previously shown to induce a significant incidence of transitional cell carcinoma of the bladder when administered to rats either immediately or beginning 2 weeks after ulceration of the bladder epithelium induced by freezing or cyclophosphamide injection." | 7.67 | Initiation of urinary bladder carcinogenesis in rats by freeze ulceration with sodium saccharin promotion. ( Cohen, SM; Greenfield, RE; Hasegawa, R; Murasaki, G; Suzuki, T, 1985) |
| " Ulceration of the bladder, induced by cyclophosphamide (CP) or freezing, followed by sodium saccharin in the diet results in the induction of bladder cancer." | 3.67 | Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin. ( Cohen, SM; Hasegawa, R; Murasaki, G; Suzuki, T, 1984) |
| "Sodium saccharin was previously shown to induce a significant incidence of transitional cell carcinoma of the bladder when administered to rats either immediately or beginning 2 weeks after ulceration of the bladder epithelium induced by freezing or cyclophosphamide injection." | 3.67 | Initiation of urinary bladder carcinogenesis in rats by freeze ulceration with sodium saccharin promotion. ( Cohen, SM; Greenfield, RE; Hasegawa, R; Murasaki, G; Suzuki, T, 1985) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Suzuki, T | 2 |
| Hasegawa, R | 2 |
| Murasaki, G | 3 |
| Cohen, SM | 4 |
| Greenfield, RE | 1 |
Other Studies
4 other studies available for saccharin and Ulcer
| Article | Year |
|---|---|
Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin.
Topics: Agglutination; Animals; Carcinogens; Concanavalin A; Cyclophosphamide; Dose-Response Relationship, D | 1984 |
Effect of sodium saccharin on urinary bladder epithelial regenerative hyperplasia following freeze ulceration.
Topics: Animals; Autoradiography; Cell Division; Freezing; Hyperplasia; Male; Microscopy, Electron, Scanning | 1983 |
Promotion in urinary bladder carcinogenesis.
Topics: Animals; Cell Division; Cocarcinogenesis; FANFT; Neoplasms, Experimental; Rats; Saccharin; Ulcer; Ur | 1983 |
Initiation of urinary bladder carcinogenesis in rats by freeze ulceration with sodium saccharin promotion.
Topics: Animals; Carcinoma, Transitional Cell; Cocarcinogenesis; Freezing; Hyperplasia; Male; Rats; Rats, In | 1985 |