saccharin has been researched along with Rhinitis in 14 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of the drug Sinupret extract not only contributes to a more rapid improvement in the general well-being of patients and a decrease in the severity of complaints, but also leads to an improvement in the objective picture of the disease (rhinoscopy, the results of anterior active rhinomanometry, saccharin test) compared with the control group, favorably affects the quality life of patients, causes a decrease in economic and social costs against the background of the development of acute viral rhinosinusitis." | 4.31 | [Possibilities of usage of modern herbal medicinal product in the treatment of patients with acute viral rhinosinusitis]. ( Nikiforova, AN; Nikiforova, GN; Shevchik, EA; Svistushkin, VM; Toldanov, AV; Zolotova, AV, 2023) |
| "To determine the correlation between rhinosinusitis symptoms as assessed by the Sino-Nasal Outcomes Test-20 (SNOT-20) and mucociliary clearance as assessed by the saccharin method." | 3.73 | Relationship between rhinosinusitis symptoms and mucociliary clearance time. ( Boatsman, JE; Calhoun, KH; Ryan, MW, 2006) |
| "Nasal mucociliary clearance was measured using a saccharin technique in 172 patients with perennial rhinitis (76 also had asthma) and in 121 patients with chronic infected rhinosinusitis (40 had asthma, 35 had bronchiectasis)." | 3.67 | Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease. ( Cole, PJ; Greenstone, MA; Mackay, IS; Stanley, PJ; Wilson, R, 1985) |
| "Saccharin transit time was significantly increased (p<0." | 2.73 | Comparison of microdebrider-assisted inferior turbinoplasty and submucosal resection for children with hypertrophic inferior turbinates. ( Chen, YL; Huang, HM; Liu, CM, 2007) |
| "Rhinosinusitis is a common post-RT side-effect in NPC patients." | 1.32 | Nasal and paranasal sinus changes after radiotherapy for nasopharyngeal carcinoma. ( Al-Badawy, S; Kamel, R; Kandil, T; Khairy, A; Sabry, A, 2004) |
| "Nasal obstruction was estimated by subjective scoring and mucociliary transport was determined by the saccharin method." | 1.30 | Nasal mucociliary transport is impaired at altitude. ( Barry, PW; Mason, NP; O'Callaghan, C, 1997) |
| "Chronic rhinitis is the manifestation of a heterogeneous group of disease entities and often proves difficult to manage successfully." | 1.30 | Assessment of mucociliary transport in patients with chronic mucoid rhinitis. ( Anderson, P; Boivin, CM; Drake-Lee, AB; Prior, MJ; Schofield, K, 1999) |
| "The saccharin test was carried out in a randomly selected sample of schoolchildren (142 boys and 153 girls, age range 11-14 years) to determine the variability and reproducibility of the test and to assess whether it could be used as a screening test for nasal mucociliary clearance." | 1.28 | Measurement of nasal mucociliary clearance. ( Agabiti, N; Bonfitto, P; Cole, PJ; Corbo, GM; Foresi, A; Mugnano, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chitsuthipakorn, W | 1 |
| Kanjanawasee, D | 1 |
| Hoang, MP | 1 |
| Seresirikachorn, K | 1 |
| Snidvongs, K | 1 |
| Svistushkin, VM | 1 |
| Nikiforova, GN | 1 |
| Toldanov, AV | 1 |
| Zolotova, AV | 1 |
| Shevchik, EA | 1 |
| Nikiforova, AN | 1 |
| Kamel, R | 1 |
| Al-Badawy, S | 1 |
| Khairy, A | 1 |
| Kandil, T | 1 |
| Sabry, A | 1 |
| Boatsman, JE | 1 |
| Calhoun, KH | 1 |
| Ryan, MW | 1 |
| Chen, YL | 1 |
| Liu, CM | 1 |
| Huang, HM | 1 |
| Stringer, SP | 1 |
| Stiles, W | 1 |
| Slattery, WH | 1 |
| Krumerman, J | 1 |
| Parsons, JT | 1 |
| Mendenhall, WM | 1 |
| Cassisi, NJ | 1 |
| Mahakit, P | 1 |
| Pumhirun, P | 1 |
| Rose, GK | 1 |
| Mason, JD | 1 |
| Varma, SK | 1 |
| Barry, PW | 1 |
| Mason, NP | 1 |
| O'Callaghan, C | 1 |
| Prior, MJ | 1 |
| Schofield, K | 1 |
| Boivin, CM | 1 |
| Anderson, P | 1 |
| Drake-Lee, AB | 1 |
| England, RJ | 1 |
| Anthony, R | 1 |
| Homer, JJ | 1 |
| Martin-Hirsch, DP | 1 |
| Corbo, GM | 1 |
| Foresi, A | 1 |
| Bonfitto, P | 1 |
| Mugnano, A | 1 |
| Agabiti, N | 1 |
| Cole, PJ | 2 |
| Deitmer, T | 1 |
| Stanley, PJ | 1 |
| Wilson, R | 1 |
| Greenstone, MA | 1 |
| Mackay, IS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison[NCT00626366] | 18 participants (Actual) | Interventional | 2008-03-12 | Completed | |||
| A Comparative, Multicenter and Randomized Study Evaluating the Safety and Efficacy of RESPIMER® Netiflow® Versus Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy in the Treatment of Nasal Polyposis.[NCT02559284] | 189 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
CT scan scored for distribution contrast delivered by nasal spray or drops within subsets in the nasal cavity. The sinonasal cavity was divided into twenty-one subsites on each side of the nasal cavity. The interpreters scored for the presence (1) or absence (0) of contrast from the nasal spray or nasal drops within each subsite. Left and right sides were interpreted separately for a possible total score of 0-42 for each CT scan. (NCT00626366)
Timeframe: 2 months
| Intervention | nasal cavities (right and left sides) (Number) | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nasal vestibule | Inferior upper nasal vault | Superior upper nasal vault | Anterior floor of nose | Anterior inferior meatus | Anterior inferior nasal cavity | Posterior floor of nose | Posterior inferior meatus | Posterior inferior nasal cavity | Anterior middle nasal cavity | Anterior olfactory cleft | Posterior middle nasal cavity | Posterior olfactory cleft | Anterior middle meatus | Anterior ethmoid | Osteomeatal complex | Posterior middle meatus | Posterior ethmoid | Frontal recess | Sphenoethmoid recess | Nasopharynx | |
| Nasal Drops | 17 | 17 | 6 | 4 | 0 | 6 | 0 | 1 | 1 | 5 | 4 | 4 | 4 | 2 | 1 | 1 | 1 | 2 | 2 | 4 | 2 |
| Nasal Spray | 18 | 16 | 0 | 12 | 16 | 15 | 9 | 9 | 3 | 3 | 1 | 2 | 1 | 4 | 2 | 2 | 2 | 1 | 0 | 2 | 8 |
1 review available for saccharin and Rhinitis
| Article | Year |
|---|---|
Benefits of nasal saline treatment in acute rhinosinusitis: Systematic review and meta-analysis.
Topics: Acute Disease; Adult; Chronic Disease; Humans; Quality of Life; Rhinitis; Saccharin; Saline Solution | 2022 |
1 trial available for saccharin and Rhinitis
| Article | Year |
|---|---|
Comparison of microdebrider-assisted inferior turbinoplasty and submucosal resection for children with hypertrophic inferior turbinates.
Topics: Adolescent; Child; Debridement; Edema; Endoscopy; Female; Follow-Up Studies; Humans; Hypertrophy; Ma | 2007 |
12 other studies available for saccharin and Rhinitis
| Article | Year |
|---|---|
[Possibilities of usage of modern herbal medicinal product in the treatment of patients with acute viral rhinosinusitis].
Topics: Acute Disease; Humans; Phytotherapy; Plant Extracts; Rhinitis; Saccharin; Sinusitis; Treatment Outco | 2023 |
Nasal and paranasal sinus changes after radiotherapy for nasopharyngeal carcinoma.
Topics: Adolescent; Adult; Aged; Carcinoma; Child; Edema; Endoscopy; Female; Humans; Male; Middle Aged; Muco | 2004 |
Relationship between rhinosinusitis symptoms and mucociliary clearance time.
Topics: Adult; Cross-Sectional Studies; Humans; Mucociliary Clearance; Quality of Life; Rhinitis; Saccharin; | 2006 |
Nasal mucociliary clearance after radiation therapy.
Topics: Administration, Intranasal; Administration, Oral; Adult; Aged; Aged, 80 and over; Facial Pain; Femal | 1995 |
A preliminary study of nasal mucociliary clearance in smokers, sinusitis and allergic rhinitis patients.
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Mucociliary Clearance; Nasal Mucosa; Rhi | 1995 |
Effect of facial burns on the nasal mucosa.
Topics: Adult; Aged; Burns; Endoscopy; Facial Injuries; Humans; Male; Middle Aged; Mucociliary Clearance; Na | 1996 |
Nasal mucociliary transport is impaired at altitude.
Topics: Adolescent; Adult; Altitude; Confidence Intervals; Female; Humans; Indicators and Reagents; Male; Mi | 1997 |
Assessment of mucociliary transport in patients with chronic mucoid rhinitis.
Topics: Chronic Disease; Humans; Kartagener Syndrome; Mucociliary Clearance; Mucus; Nasal Mucosa; Radiopharm | 1999 |
Nasal pH and saccharin clearance are unrelated in the physiologically normal nose.
Topics: Humans; Hydrogen-Ion Concentration; Male; Mucociliary Clearance; Nasal Mucosa; Rhinitis; Saccharin | 2000 |
Measurement of nasal mucociliary clearance.
Topics: Adolescent; Asthma; Child; Female; Humans; Male; Mucociliary Clearance; Nasal Mucosa; Reference Valu | 1989 |
A modification of the saccharine test for nasal mucociliary clearance.
Topics: Animals; Anion Exchange Resins; Chronic Disease; Ciliary Motility Disorders; Common Cold; Dogs; Huma | 1986 |
Abnormal nasal mucociliary clearance in patients with rhinitis and its relationship to concomitant chest disease.
Topics: Adolescent; Adult; Asthma; Bronchiectasis; Cilia; Female; Humans; Male; Middle Aged; Mucus; Nose; Rh | 1985 |