saccharin has been researched along with Nausea in 14 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For acute nausea, the potential of cannabinoid pretreatment(s) to reduce LiCl-induced nausea paired with saccharin was evaluated in a subsequent drug free taste reactivity test, followed by a taste avoidance test." | 7.81 | Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping. ( Limebeer, CL; Parker, LA; Rock, EM, 2015) |
| "This study examined whether rats can simultaneously learn to associate lithium chloride (LiCl)-induced nausea with both contextual and intravascular taste cues." | 7.77 | Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea. ( Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "For acute nausea, the potential of cannabinoid pretreatment(s) to reduce LiCl-induced nausea paired with saccharin was evaluated in a subsequent drug free taste reactivity test, followed by a taste avoidance test." | 3.81 | Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping. ( Limebeer, CL; Parker, LA; Rock, EM, 2015) |
| "This study examined the effects of the bacterial endotoxin, lipopolysaccharide (LPS), on the establishment of anticipatory nausea and conditioned taste avoidance in a simultaneous conditioning paradigm using an intravascular/intraperitoneal saccharin taste." | 3.78 | Lipopolysaccharide inhibits the simultaneous establishment of LiCl-induced anticipatory nausea and intravascularly conditioned taste avoidance in the rat. ( Cloutier, CJ; Kavaliers, M; Ossenkopp, KP, 2012) |
| "This study examined whether rats can simultaneously learn to associate lithium chloride (LiCl)-induced nausea with both contextual and intravascular taste cues." | 3.77 | Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea. ( Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "The conditioned gaping model of nausea in rats was used to compare the CB(1) receptor antagonist/inverse agonist, AM251, and the CB(1) receptor neutral antagonists, AM6527 (centrally and peripherally active) and AM6545 (peripherally active), in potentiating conditioned gaping produced by lithium chloride (LiCl) solution." | 3.76 | Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats. ( Bedard, H; Lang, ST; Limebeer, CL; Makriyannis, A; Ossenkopp, KP; Parker, LA; Vemuri, VK, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Su, S | 1 |
| Wei, Z | 1 |
| Huang, H | 1 |
| Yoshizawa, T | 1 |
| Inui, T | 1 |
| Funahashi, M | 1 |
| Rosania, K | 1 |
| Rock, EM | 1 |
| Limebeer, CL | 4 |
| Parker, LA | 5 |
| Itoga, CA | 1 |
| Berridge, KC | 1 |
| Aldridge, JW | 1 |
| Vemuri, VK | 1 |
| Bedard, H | 1 |
| Lang, ST | 1 |
| Ossenkopp, KP | 3 |
| Makriyannis, A | 1 |
| Cloutier, CJ | 2 |
| Cross-Mellor, SK | 1 |
| Kavaliers, M | 2 |
| Tuerke, KJ | 2 |
| Winters, BD | 1 |
| Gupta, V | 1 |
| Bala, M | 1 |
| Prasad, J | 1 |
| Singh, S | 1 |
| Gupta, M | 1 |
| Fletcher, PJ | 1 |
| Miranda, MI | 1 |
| LaLumiere, RT | 1 |
| Buen, TV | 1 |
| Bermudez-Rattoni, F | 1 |
| McGaugh, JL | 1 |
| Cairnie, AB | 1 |
| Roudebush, RE | 1 |
| Bryant, HU | 1 |
14 other studies available for saccharin and Nausea
| Article | Year |
|---|---|
Conditioned nausea induced by cisplatin and emetine identified by a taste reactivity test in rats.
Topics: Animals; Avoidance Learning; Cisplatin; Emetine; Lithium Chloride; Nausea; Rats; Saccharin; Taste | 2023 |
Time and place crucial to remembered taste experiences.
Topics: Animals; Cerebrum; Humans; Memory; Mice; Nausea; Neuronal Plasticity; Saccharin; Taste | 2014 |
Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping.
Topics: Animals; Antiemetics; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dronabinol; | 2015 |
Ventral pallidal coding of a learned taste aversion.
Topics: Action Potentials; Animals; Association Learning; Avoidance Learning; Basal Forebrain; Catheters, In | 2016 |
Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats.
Topics: Administration, Oral; Animals; Brain; Conditioning, Classical; Disease Models, Animal; Dose-Response | 2010 |
Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea.
Topics: Animals; Anticipation, Psychological; Antimanic Agents; Avoidance Learning; Behavior, Animal; Condit | 2011 |
Ondansetron interferes with unconditioned lying-on belly and acquisition of conditioned gaping induced by LiCl as models of nausea-induced behaviors in rats.
Topics: Analysis of Variance; Animals; Antiemetics; Avoidance Learning; Conditioning, Classical; Disease Mod | 2012 |
Leaves of Hippophae rhamnoides prevent taste aversion in gamma-irradiated rats.
Topics: Animals; Antiemetics; Antioxidants; Behavior, Animal; Conditioning, Classical; Corticosterone; Dieta | 2011 |
Lipopolysaccharide inhibits the simultaneous establishment of LiCl-induced anticipatory nausea and intravascularly conditioned taste avoidance in the rat.
Topics: Analysis of Variance; Animals; Anticipation, Psychological; Avoidance Learning; Behavior, Animal; Bo | 2012 |
Double dissociation between regulation of conditioned disgust and taste avoidance by serotonin availability at the 5-HT(3) receptor in the posterior and anterior insular cortex.
Topics: 5,6-Dihydroxytryptamine; Animals; Avoidance Learning; Biguanides; Cerebral Cortex; Conditioning, Cla | 2012 |
Blockade of noradrenergic receptors in the basolateral amygdala impairs taste memory.
Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Conditioning, Classical; Lithium | 2003 |
Adverse effects of radioprotector WR2721.
Topics: Amifostine; Animals; Conditioning, Psychological; Diet; Dose-Response Relationship, Drug; Male; Naus | 1983 |
Delta-9-tetrahydrocannabinol interferes with the establishment and the expression of conditioned rejection reactions produced by cyclophosphamide: a rat model of nausea.
Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Cyclophosphamid | 1999 |
Conditioned immunosuppression of a murine delayed type hypersensitivity response: dissociation from corticosterone elevation.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Corticosterone; Cyclophosphamide; Dexamethason | 1991 |