saccharin and Nausea
saccharin has been researched along with Nausea in 14 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "For acute nausea, the potential of cannabinoid pretreatment(s) to reduce LiCl-induced nausea paired with saccharin was evaluated in a subsequent drug free taste reactivity test, followed by a taste avoidance test." | 7.81 | Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping. ( Limebeer, CL; Parker, LA; Rock, EM, 2015) |
| "This study examined whether rats can simultaneously learn to associate lithium chloride (LiCl)-induced nausea with both contextual and intravascular taste cues." | 7.77 | Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea. ( Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "For acute nausea, the potential of cannabinoid pretreatment(s) to reduce LiCl-induced nausea paired with saccharin was evaluated in a subsequent drug free taste reactivity test, followed by a taste avoidance test." | 3.81 | Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping. ( Limebeer, CL; Parker, LA; Rock, EM, 2015) |
| "This study examined the effects of the bacterial endotoxin, lipopolysaccharide (LPS), on the establishment of anticipatory nausea and conditioned taste avoidance in a simultaneous conditioning paradigm using an intravascular/intraperitoneal saccharin taste." | 3.78 | Lipopolysaccharide inhibits the simultaneous establishment of LiCl-induced anticipatory nausea and intravascularly conditioned taste avoidance in the rat. ( Cloutier, CJ; Kavaliers, M; Ossenkopp, KP, 2012) |
| "This study examined whether rats can simultaneously learn to associate lithium chloride (LiCl)-induced nausea with both contextual and intravascular taste cues." | 3.77 | Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea. ( Cloutier, CJ; Cross-Mellor, SK; Kavaliers, M; Ossenkopp, KP, 2011) |
| "The conditioned gaping model of nausea in rats was used to compare the CB(1) receptor antagonist/inverse agonist, AM251, and the CB(1) receptor neutral antagonists, AM6527 (centrally and peripherally active) and AM6545 (peripherally active), in potentiating conditioned gaping produced by lithium chloride (LiCl) solution." | 3.76 | Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats. ( Bedard, H; Lang, ST; Limebeer, CL; Makriyannis, A; Ossenkopp, KP; Parker, LA; Vemuri, VK, 2010) |
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Su, S | 1 |
| Wei, Z | 1 |
| Huang, H | 1 |
| Yoshizawa, T | 1 |
| Inui, T | 1 |
| Funahashi, M | 1 |
| Rosania, K | 1 |
| Rock, EM | 1 |
| Limebeer, CL | 4 |
| Parker, LA | 5 |
| Itoga, CA | 1 |
| Berridge, KC | 1 |
| Aldridge, JW | 1 |
| Vemuri, VK | 1 |
| Bedard, H | 1 |
| Lang, ST | 1 |
| Ossenkopp, KP | 3 |
| Makriyannis, A | 1 |
| Cloutier, CJ | 2 |
| Cross-Mellor, SK | 1 |
| Kavaliers, M | 2 |
| Tuerke, KJ | 2 |
| Winters, BD | 1 |
| Gupta, V | 1 |
| Bala, M | 1 |
| Prasad, J | 1 |
| Singh, S | 1 |
| Gupta, M | 1 |
| Fletcher, PJ | 1 |
| Miranda, MI | 1 |
| LaLumiere, RT | 1 |
| Buen, TV | 1 |
| Bermudez-Rattoni, F | 1 |
| McGaugh, JL | 1 |
| Cairnie, AB | 1 |
| Roudebush, RE | 1 |
| Bryant, HU | 1 |
Other Studies
14 other studies available for saccharin and Nausea
| Article | Year |
|---|---|
Conditioned nausea induced by cisplatin and emetine identified by a taste reactivity test in rats.
Topics: Animals; Avoidance Learning; Cisplatin; Emetine; Lithium Chloride; Nausea; Rats; Saccharin; Taste | 2023 |
Time and place crucial to remembered taste experiences.
Topics: Animals; Cerebrum; Humans; Memory; Mice; Nausea; Neuronal Plasticity; Saccharin; Taste | 2014 |
Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley) models of conditioned gaping.
Topics: Animals; Antiemetics; Cannabinoids; Conditioning, Psychological; Disease Models, Animal; Dronabinol; | 2015 |
Ventral pallidal coding of a learned taste aversion.
Topics: Action Potentials; Animals; Association Learning; Avoidance Learning; Basal Forebrain; Catheters, In | 2016 |
Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats.
Topics: Administration, Oral; Animals; Brain; Conditioning, Classical; Disease Models, Animal; Dose-Response | 2010 |
Simultaneous conditioning of "gaping" responses and taste avoidance in rats injected with LiCl and saccharin: examining the role of context and taste cues in the rodent model of anticipatory nausea.
Topics: Animals; Anticipation, Psychological; Antimanic Agents; Avoidance Learning; Behavior, Animal; Condit | 2011 |
Ondansetron interferes with unconditioned lying-on belly and acquisition of conditioned gaping induced by LiCl as models of nausea-induced behaviors in rats.
Topics: Analysis of Variance; Animals; Antiemetics; Avoidance Learning; Conditioning, Classical; Disease Mod | 2012 |
Leaves of Hippophae rhamnoides prevent taste aversion in gamma-irradiated rats.
Topics: Animals; Antiemetics; Antioxidants; Behavior, Animal; Conditioning, Classical; Corticosterone; Dieta | 2011 |
Lipopolysaccharide inhibits the simultaneous establishment of LiCl-induced anticipatory nausea and intravascularly conditioned taste avoidance in the rat.
Topics: Analysis of Variance; Animals; Anticipation, Psychological; Avoidance Learning; Behavior, Animal; Bo | 2012 |
Double dissociation between regulation of conditioned disgust and taste avoidance by serotonin availability at the 5-HT(3) receptor in the posterior and anterior insular cortex.
Topics: 5,6-Dihydroxytryptamine; Animals; Avoidance Learning; Biguanides; Cerebral Cortex; Conditioning, Cla | 2012 |
Blockade of noradrenergic receptors in the basolateral amygdala impairs taste memory.
Topics: Adrenergic beta-Antagonists; Amygdala; Animals; Avoidance Learning; Conditioning, Classical; Lithium | 2003 |
Adverse effects of radioprotector WR2721.
Topics: Amifostine; Animals; Conditioning, Psychological; Diet; Dose-Response Relationship, Drug; Male; Naus | 1983 |
Delta-9-tetrahydrocannabinol interferes with the establishment and the expression of conditioned rejection reactions produced by cyclophosphamide: a rat model of nausea.
Topics: Animals; Antiemetics; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Cyclophosphamid | 1999 |
Conditioned immunosuppression of a murine delayed type hypersensitivity response: dissociation from corticosterone elevation.
Topics: Animals; Avoidance Learning; Conditioning, Classical; Corticosterone; Cyclophosphamide; Dexamethason | 1991 |