saccharin has been researched along with Nasal Obstruction in 12 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Nasal Obstruction: Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Microdebrider-assisted inferior turbinoplasty with lateralization appears to be as effective as submucosal resection at relieving nasal symptoms and decreasing total nasal resistance and saccharin transit times for more than 3 years in patients with perennial allergic rhinitis who have had substantial nasal obstruction." | 5.13 | Long-term efficacy of microdebrider-assisted inferior turbinoplasty with lateralization for hypertrophic inferior turbinates in patients with perennial allergic rhinitis. ( Chen, YL; Huang, HM; Tan, CT, 2008) |
| " Saccharin transit time and ciliary beat frequency were preserved after RFTVR CONCLUSION: RFTVR for the turbinate may be useful as an alternative approach for the treatment of chronic turbinate hypertrophy." | 5.09 | Changes of nasal function after temperature-controlled radiofrequency tissue volume reduction for the turbinate. ( Kim, DY; Kwon, TY; Lee, CH; Lee, HJ; Min, YG; Park, SW; Rhee, CS; Won, TB, 2001) |
| " Saccharin time, Sniffin' Sticks, Turkish Nasal Obstruction Symptom Evaluation and Sino-Nasal Outcome Test 22 scores were compared." | 4.12 | The residual effect of coronovirus disease 2019 on olfactory acuity and mucociliary clearance time: a cross-sectional, controlled study. ( Kandemir, S; Pamuk, AE, 2022) |
| "Compared to preoperative values, the symptom scores (nasal obstruction, sneezing, rhinorrhea, and snoring), mean total nasal resistance, and mean saccharin transit time all improved significantly at 6 months, 1, 2, and 3 years after surgery in MAIT group (P < ." | 3.75 | Microdebrider-assisted versus radiofrequency-assisted inferior turbinoplasty. ( Huang, HM; Lee, FP; Lin, KN; Liu, CM; Tan, CD, 2009) |
| "Saccharin transit time was significantly increased (p<0." | 2.73 | Comparison of microdebrider-assisted inferior turbinoplasty and submucosal resection for children with hypertrophic inferior turbinates. ( Chen, YL; Huang, HM; Liu, CM, 2007) |
| "Nasal obstruction was estimated by subjective scoring and mucociliary transport was determined by the saccharin method." | 1.30 | Nasal mucociliary transport is impaired at altitude. ( Barry, PW; Mason, NP; O'Callaghan, C, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kandemir, S | 1 |
| Pamuk, AE | 1 |
| Kökoğlu, K | 1 |
| Vural, A | 1 |
| Liu, CM | 2 |
| Tan, CD | 1 |
| Lee, FP | 1 |
| Lin, KN | 1 |
| Huang, HM | 3 |
| Lee, DH | 1 |
| Cingi, C | 1 |
| Unlu, HH | 1 |
| Songu, M | 1 |
| Yalcin, S | 1 |
| Topcu, I | 1 |
| Cakli, H | 1 |
| Bal, C | 1 |
| Barr, GS | 1 |
| Tewary, AK | 1 |
| Chen, YL | 2 |
| Tan, CT | 1 |
| Rose, GK | 1 |
| Mason, JD | 1 |
| Varma, SK | 1 |
| Barry, PW | 1 |
| Mason, NP | 1 |
| O'Callaghan, C | 1 |
| Homer, JJ | 1 |
| Dowley, AC | 1 |
| Condon, L | 1 |
| El-Jassar, P | 1 |
| Sood, S | 1 |
| Rhee, CS | 1 |
| Kim, DY | 1 |
| Won, TB | 1 |
| Lee, HJ | 1 |
| Park, SW | 1 |
| Kwon, TY | 1 |
| Lee, CH | 1 |
| Min, YG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative, Multicenter and Randomized Study Evaluating the Safety and Efficacy of RESPIMER® Netiflow® Versus Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy in the Treatment of Nasal Polyposis.[NCT02559284] | 189 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for saccharin and Nasal Obstruction
| Article | Year |
|---|---|
Seawater gel in allergic rhinitis: entrapment effect and mucociliary clearance compared with saline.
Topics: Administration, Intranasal; Adolescent; Adult; Female; Humans; Male; Middle Aged; Mucociliary Cleara | 2010 |
Alteration of airflow and mucociliary transport in normal subjects.
Topics: Administration, Intranasal; Adult; Female; Humans; Male; Mucociliary Clearance; Nasal Obstruction; P | 1993 |
Comparison of microdebrider-assisted inferior turbinoplasty and submucosal resection for children with hypertrophic inferior turbinates.
Topics: Adolescent; Child; Debridement; Edema; Endoscopy; Female; Follow-Up Studies; Humans; Hypertrophy; Ma | 2007 |
Long-term efficacy of microdebrider-assisted inferior turbinoplasty with lateralization for hypertrophic inferior turbinates in patients with perennial allergic rhinitis.
Topics: Adult; Anesthesia, Local; Debridement; Endoscopy; Female; Follow-Up Studies; Humans; Hypertrophy; Ma | 2008 |
The effect of hypertonicity on nasal mucociliary clearance.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Mucociliary Clear | 2000 |
Changes of nasal function after temperature-controlled radiofrequency tissue volume reduction for the turbinate.
Topics: Acoustics; Adult; Airway Resistance; Butanols; Catheter Ablation; Cilia; Female; Follow-Up Studies; | 2001 |
6 other studies available for saccharin and Nasal Obstruction
| Article | Year |
|---|---|
The residual effect of coronovirus disease 2019 on olfactory acuity and mucociliary clearance time: a cross-sectional, controlled study.
Topics: COVID-19; Cross-Sectional Studies; Humans; Mucociliary Clearance; Nasal Obstruction; Olfaction Disor | 2022 |
Evaluation of the effect of inferior turbinate outfracture on nasolacrimal transit time by saccharin test.
Topics: Adult; Female; Humans; Male; Mucociliary Clearance; Nasal Obstruction; Nasolacrimal Duct; Outcome As | 2019 |
Microdebrider-assisted versus radiofrequency-assisted inferior turbinoplasty.
Topics: Adolescent; Adult; Analysis of Variance; Case-Control Studies; Debridement; Electrocoagulation; Endo | 2009 |
In reference to Microdebrider-assisted versus radiofrequency-assisted inferior turbinoplasty.
Topics: Adolescent; Adult; Debridement; Electrocoagulation; Endoscopy; Female; Humans; Male; Middle Aged; Na | 2009 |
Effect of facial burns on the nasal mucosa.
Topics: Adult; Aged; Burns; Endoscopy; Facial Injuries; Humans; Male; Middle Aged; Mucociliary Clearance; Na | 1996 |
Nasal mucociliary transport is impaired at altitude.
Topics: Adolescent; Adult; Altitude; Confidence Intervals; Female; Humans; Indicators and Reagents; Male; Mi | 1997 |