saccharin has been researched along with Muscle Relaxation in 4 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inhaled bitter tastants decreased airway obstruction in a mouse model of asthma." | 1.36 | Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction. ( An, SS; Deshpande, DA; Liggett, SB; McIlmoyle, EL; Robinett, KS; Schillinger, RM; Sham, JS; Wang, WC, 2010) |
| "Nitroxyl was measured gas chromatographically as its dimerization/dehydration product N2O." | 1.29 | Prodrugs of nitroxyl as potential aldehyde dehydrogenase inhibitors vis-a-vis vascular smooth muscle relaxants. ( DeMaster, EG; Elberling, JA; Fukuto, JM; Kawle, SP; Nagasawa, HT, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manson, ML | 1 |
| Säfholm, J | 1 |
| Al-Ameri, M | 1 |
| Bergman, P | 1 |
| Orre, AC | 1 |
| Swärd, K | 1 |
| James, A | 1 |
| Dahlén, SE | 1 |
| Adner, M | 1 |
| Deshpande, DA | 1 |
| Wang, WC | 1 |
| McIlmoyle, EL | 1 |
| Robinett, KS | 1 |
| Schillinger, RM | 1 |
| An, SS | 1 |
| Sham, JS | 1 |
| Liggett, SB | 1 |
| Morice, AH | 1 |
| Bennett, RT | 1 |
| Chaudhry, MA | 1 |
| Cowen, ME | 1 |
| Griffin, SC | 1 |
| Loubani, M | 1 |
| Nagasawa, HT | 1 |
| Kawle, SP | 1 |
| Elberling, JA | 1 |
| DeMaster, EG | 1 |
| Fukuto, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Collection of Gastrointestinal Tissue Samples for the Characterization and ex Vivo Functional Assessment of Chemoreceptors[NCT02859116] | 8 participants (Actual) | Observational | 2016-07-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for saccharin and Muscle Relaxation
| Article | Year |
|---|---|
Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle.
Topics: Aged; Animals; Aorta, Thoracic; Chloroquine; Colon; Dextromethorphan; Female; Guinea Pigs; Humans; I | 2014 |
Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction.
Topics: Airway Obstruction; Animals; Asthma; Bronchi; Bronchoconstriction; Calcium Signaling; Cell Separatio | 2010 |
Effect of bitter tastants on human bronchi.
Topics: Bronchi; Bronchoconstriction; Dose-Response Relationship, Drug; Humans; Isoproterenol; Methacholine | 2011 |
Prodrugs of nitroxyl as potential aldehyde dehydrogenase inhibitors vis-a-vis vascular smooth muscle relaxants.
Topics: Aldehyde Dehydrogenase; Animals; Biotransformation; Drug Stability; Free Radicals; Male; Muscle Rela | 1995 |