saccharin has been researched along with Morphine Dependence in 11 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YC | 1 |
| Chiu, WC | 1 |
| Cheng, CN | 1 |
| Lee, C | 1 |
| Chih Wei Huang, A | 1 |
| Radke, AK | 1 |
| Holtz, NA | 1 |
| Gewirtz, JC | 1 |
| Carroll, ME | 1 |
| Pillai, NP | 1 |
| Ramaswamy, S | 1 |
| Gopalakrishnan, V | 1 |
| Ghosh, MN | 1 |
| Belknap, JK | 2 |
| Crabbe, JC | 1 |
| Riggan, J | 1 |
| O'Toole, LA | 1 |
| Gomez, F | 1 |
| Leo, NA | 1 |
| Grigson, PS | 2 |
| Wheeler, RA | 1 |
| Wheeler, DS | 1 |
| Ballard, SM | 1 |
| Hill, SY | 1 |
| Powell, BJ | 1 |
| Villaneuva, HF | 1 |
| James, JR | 1 |
| Arezo, S | 1 |
| Rosecrans, JA | 1 |
| Parker, L | 1 |
| Failor, A | 1 |
| Weidman, K | 1 |
| Jacquet, YF | 1 |
11 other studies available for saccharin and Morphine Dependence
| Article | Year |
|---|---|
Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine.
Topics: Amygdala; Animals; Conditioning, Operant; Disease Models, Animal; Hippocampus; Humans; Interleukin-1 | 2021 |
Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake.
Topics: Acoustic Stimulation; Analgesics, Opioid; Animals; Breeding; Emotions; Female; Male; Morphine; Morph | 2013 |
Effect of cholinergic agonists and antagonists on morphine withdrawal induced aversion to saccharin drinking in rats.
Topics: Animals; Drinking Behavior; Humans; Male; Morphine Dependence; Parasympatholytics; Parasympathomimet | 1984 |
Voluntary consumption of morphine in 15 inbred mouse strains.
Topics: Animals; Male; Mice; Morphine Dependence; Quinine; Saccharin; Species Specificity; Taste | 1993 |
Morphine-induced suppression of saccharin intake is correlated with elevated corticosterone levels.
Topics: Animals; Conditioning, Psychological; Corticosterone; Drug Interactions; Eating; Male; Morphine; Mor | 2000 |
Chronic morphine treatment exaggerates the suppressive effects of sucrose and cocaine, but not lithium chloride, on saccharin intake in Sprague-Dawley rats.
Topics: Animals; Association Learning; Cocaine; Conditioning, Classical; Dose-Response Relationship, Drug; D | 2001 |
Acquired preference for morphine but no d-amphetamine as a result of saccharine adulteration.
Topics: Animals; Choice Behavior; Dextroamphetamine; Humans; Male; Morphine Dependence; Rats; Reinforcement, | 1976 |
Withdrawal from nicotine fails to produce a conditioned taste aversion to saccharine in rats and mice.
Topics: Animals; Avoidance Learning; Male; Mice; Mice, Inbred ICR; Morphine Dependence; Nicotine; Rats; Rats | 1990 |
Physical dependence induced by the voluntary consumption of morphine in inbred mice.
Topics: Animals; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Morphine Dependence; Naloxone; | 1990 |
Conditioned preferences in the rat with an unnatural need state: morphine withdrawal.
Topics: Acetates; Animals; Appetite; Avoidance Learning; Conditioning, Psychological; Drinking Behavior; Fem | 1973 |
Conditioned aversion during morphine maintenance in mice and rats.
Topics: Animals; Avoidance Learning; Body Weight; Conditioning, Classical; Dose-Response Relationship, Drug; | 1973 |