saccharin has been researched along with Liver Neoplasms in 12 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The carcinogenic dose-response relationship for genotoxic chemicals (such as 2-acetylaminofluorene) was also due in part to increased cell proliferation." | 2.38 | Cell proliferation in carcinogenesis. ( Cohen, SM; Ellwein, LB, 1990) |
| " The dose-response of the promoters were examined in both sexes of rats by administration of saccharin at doses of 0." | 1.27 | Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat. ( Fukushima, S; Ito, N; Nakanishi, K; Shirai, T, 1983) |
| "Deaths from cancer (128) were significantly fewer than expected (168), mainly because of a deficit in the number of deaths from cancers related to smoking (cancers of the buccal cavity and pharynx, oesophagus, respiratory system, and bladder)." | 1.26 | Cancer mortality and saccharin consumption in diabetics. ( Adelstein, AM; Armstrong, B; Donovan, JW; Lea, AJ; Ruttle, S; White, GC, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Z | 1 |
| Li, M | 1 |
| Yuan, Y | 1 |
| Wang, Q | 1 |
| Yan, L | 1 |
| Gu, J | 1 |
| Pereira, MA | 1 |
| Herren, SL | 1 |
| Britt, AL | 1 |
| Hirose, M | 1 |
| Shirai, T | 2 |
| Tsuda, H | 3 |
| Fukushima, S | 3 |
| Ogiso, T | 1 |
| Ito, N | 5 |
| Imaida, K | 2 |
| Kurata, Y | 1 |
| Nakanishi, K | 2 |
| Tatematsu, M | 2 |
| Hasegawa, R | 1 |
| Murasaki, G | 1 |
| Armstrong, B | 1 |
| Lea, AJ | 1 |
| Adelstein, AM | 1 |
| Donovan, JW | 1 |
| White, GC | 1 |
| Ruttle, S | 1 |
| Cohen, SM | 1 |
| Ellwein, LB | 1 |
| Rudali, G | 1 |
| Ershoff, BH | 1 |
| Bajwa, GS | 1 |
2 reviews available for saccharin and Liver Neoplasms
| Article | Year |
|---|---|
Cell proliferation in carcinogenesis.
Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Division; Humans; Liver; Liver Neoplasms; Mice; Mi | 1990 |
The cyclamate story unfolds.
Topics: Animals; Behavior, Animal; Body Weight; Cyclamates; Embryo, Mammalian; Enzyme Induction; Female; Gro | 1970 |
10 other studies available for saccharin and Liver Neoplasms
| Article | Year |
|---|---|
Cancer/testis antigens and clinical risk factors for liver metastasis of colorectal cancer: a predictive panel.
Topics: Acetaminophen; Adult; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Colorectal Neoplasms | 2010 |
Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
Topics: Animals; Cocarcinogenesis; gamma-Glutamyltransferase; Liver Neoplasms; Liver Neoplasms, Experimental | 1983 |
Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethylnitrosamine orally.
Topics: Animals; Carcinogens; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experi | 1981 |
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.
Topics: Adenocarcinoma, Papillary; Animals; Cocarcinogenesis; Liver Neoplasms; Male; Methylnitrosourea; Nitr | 1983 |
Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dose-Response Relationshi | 1983 |
Analysis of the effects of promoting agents on liver and urinary bladder carcinogenesis in rats.
Topics: Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Hyperplasia; Liver Neoplas | 1982 |
Effects of various promoters on the induction of hyperplastic nodules in rat liver.
Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Hyperplasia; | 1980 |
Cancer mortality and saccharin consumption in diabetics.
Topics: Adult; Age Factors; Aged; Coronary Disease; Diabetes Complications; Diabetes Mellitus; England; Fema | 1976 |
[The cancer-risk in man from synthetic sweetening agents].
Topics: Animals; Carcinoma, Hepatocellular; Cyclamates; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma, N | 1971 |
Inhibitory effect of sodium cyclamate and sodium saccharin on tumor induction by 2-acetylaminofluorene in rats.
Topics: Administration, Oral; Animals; Body Weight; Carcinoma, Hepatocellular; Cyclamates; Ear Canal; Ear Ne | 1974 |