Page last updated: 2024-11-04

saccharin and Innate Inflammatory Response

saccharin has been researched along with Innate Inflammatory Response in 5 studies

Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.

Research Excerpts

ExcerptRelevanceReference
" Since the artificial sweetener saccharin is known to depict bacteriostatic and microbiome-modulating properties, we hypothesized oral saccharin intake to influence intestinal inflammation and aimed at delineating its effect on acute and chronic colitis activity in mice."7.96Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. ( Derer, S; Ibrahim, SM; Künstner, A; Pagel, R; Rupp, J; Sina, C; Sünderhauf, A; Wagner, AE, 2020)
"We investigated the therapeutic effects of trehalose and saccharin on macrophage IL-1β production and eosinophilia in the mouse model of ECRS with myeloid cell-specific autophagy-related gene 7 (Atg7) deletion."4.12Sweet taste receptor agonists attenuate macrophage IL-1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells. ( Choi, GE; Choi, WS; Jang, YJ; Kim, HS; Kim, SJ; Lee, J; Park, HJ; Yi, E, 2022)
" Since the artificial sweetener saccharin is known to depict bacteriostatic and microbiome-modulating properties, we hypothesized oral saccharin intake to influence intestinal inflammation and aimed at delineating its effect on acute and chronic colitis activity in mice."3.96Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice. ( Derer, S; Ibrahim, SM; Künstner, A; Pagel, R; Rupp, J; Sina, C; Sünderhauf, A; Wagner, AE, 2020)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Lee, J1
Kim, SJ1
Choi, GE1
Yi, E1
Park, HJ1
Choi, WS1
Jang, YJ1
Kim, HS1
Sünderhauf, A1
Pagel, R1
Künstner, A1
Wagner, AE1
Rupp, J1
Ibrahim, SM1
Derer, S1
Sina, C1
Csakai, A1
Smith, C1
Davis, E1
Martinko, A1
Coulup, S1
Yin, H1
Refsgaard, LK1
Hoffmann-Petersen, J1
Sahlholt, M1
Pickering, DS1
Andreasen, JT1
Kim, A1
Feng, P1
Ohkuri, T1
Sauers, D1
Cohn, ZJ1
Chai, J1
Nelson, T1
Bachmanov, AA1
Huang, L1
Wang, H1

Other Studies

5 other studies available for saccharin and Innate Inflammatory Response

ArticleYear
Sweet taste receptor agonists attenuate macrophage IL-1β expression and eosinophilic inflammation linked to autophagy deficiency in myeloid cells.
    Clinical and translational medicine, 2022, Volume: 12, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Autophagy; Eosinophilia; Inflammation; Macrophages; Mice; Sacchar

2022
Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice.
    Nutrients, 2020, Apr-17, Volume: 12, Issue:4

    Topics: Acute Disease; Administration, Oral; Animals; Bacillus cereus; Chronic Disease; Colitis; Dextran Sul

2020
Saccharin derivatives as inhibitors of interferon-mediated inflammation.
    Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Cell Line; Databases, Chemical; Humans

2014
Modelling affective pain in mice: Effects of inflammatory hypersensitivity on place escape/avoidance behaviour, anxiety and hedonic state.
    Journal of neuroscience methods, 2016, Mar-15, Volume: 262

    Topics: Analysis of Variance; Animals; Anxiety Disorders; Avoidance Learning; Disease Models, Animal; Female

2016
Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune disease.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Action Potentials; Animals; Autoimmune Diseases; Basic Helix-Loop-Helix Transcription Factors; Cell

2012