saccharin has been researched along with Diathesis in 6 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is suggested that the induction of bladder cancer in male rats by saccharin is related to the integrity of the urothelial permeability barrier and that, in the Sprague-Dawley rat, saccharin is unable to attain a sufficient concentration in the urothelium if the barrier remains intact." | 3.67 | The mode of carcinogenic action of saccharin. ( Clayson, DB, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| West, CH | 1 |
| Weiss, JM | 1 |
| Clayson, DB | 1 |
| Honma, Y | 1 |
| Kakizoe, T | 2 |
| Komatsu, H | 1 |
| Niijima, T | 1 |
| Sugimura, T | 1 |
| Nagase, S | 2 |
| Homma, Y | 1 |
| Kondo, Y | 1 |
| Aso, Y | 1 |
| Levin, BE | 1 |
| Reed, BD | 1 |
| Slattery, ML | 1 |
| French, TK | 1 |
6 other studies available for saccharin and Diathesis
| Article | Year |
|---|---|
Intake of ethanol and reinforcing fluids in rats bred for susceptibility to stress.
Topics: Alcohol Drinking; Animals; Breeding; Disease Susceptibility; Drinking; Female; Male; Quinine; Rats; | 2006 |
The mode of carcinogenic action of saccharin.
Topics: Animals; Carcinogens; Cell Membrane Permeability; Disease Susceptibility; Epithelium; Female; Male; | 1984 |
Agglutination assay of bladder cells by Concanavalin A proved the high susceptibility of analbuminemic rats to bladder carcinogens.
Topics: 2-Naphthylamine; Agglutination Tests; Aminobiphenyl Compounds; Animals; Butylhydroxybutylnitrosamine | 1983 |
Lack of bladder carcinogenicity of dietary sodium saccharin in analbuminaemic rats, which are highly susceptible to N-nitroso-n-butyl-(4-hydroxybutyl)amine.
Topics: Administration, Oral; Animals; Body Weight; Butylhydroxybutylnitrosamine; Disease Susceptibility; Hy | 1991 |
Defective cerebral glucose utilization in diet-induced obese rats.
Topics: Animals; Autoradiography; Brain; Deoxyglucose; Diet; Disease Susceptibility; Glucose; Male; Obesity; | 1991 |
The association between dietary intake and reported history of Candida vulvovaginitis.
Topics: Adult; Calcium, Dietary; Candidiasis, Vulvovaginal; Case-Control Studies; Diet; Dietary Carbohydrate | 1989 |