Page last updated: 2024-11-04

saccharin and Diabetes Mellitus

saccharin has been researched along with Diabetes Mellitus in 23 studies

Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"Leptin is a hormone that regulates body weight homeostasis mainly via the hypothalamic functional leptin receptor Ob-Rb."1.32Leptin modulates behavioral responses to sweet substances by influencing peripheral taste structures. ( Hino, A; Koyano, K; Kusakabe, Y; Miura, H; Nakashima, K; Ninomiya, Y; Ohta, R; Shigemura, N, 2004)
"Deaths from cancer (128) were significantly fewer than expected (168), mainly because of a deficit in the number of deaths from cancers related to smoking (cancers of the buccal cavity and pharynx, oesophagus, respiratory system, and bladder)."1.26Cancer mortality and saccharin consumption in diabetics. ( Adelstein, AM; Armstrong, B; Donovan, JW; Lea, AJ; Ruttle, S; White, GC, 1976)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's2 (8.70)18.2507
2000's3 (13.04)29.6817
2010's2 (8.70)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Iizuka, K1
Thankachan, SN1
Ilamaran, M1
Ayyadurai, N1
Shanmugam, G1
Magnuson, BA1
Carakostas, MC1
Moore, NH1
Poulos, SP1
Renwick, AG1
Messier, C1
Awad-Shimoon, N1
Gagnon, M1
Desrochers, A1
Tsiakas, M1
Ilbäck, NG1
Alzin, M1
Jahrl, S1
Enghardt-Barbieri, H1
Busk, L1
COSMELLI, AJ1
Shigemura, N1
Ohta, R1
Kusakabe, Y1
Miura, H1
Hino, A1
Koyano, K1
Nakashima, K1
Ninomiya, Y1
Deniz, M1
Uslu, C1
Ogredik, EA1
Akduman, D1
Gursan, SO1
Woods, HF1
Bax, ND1
Rosenman, K1
Vialettes, B1
Héraud, G1
Roux, E1
Lenner, RA1
Armstrong, B1
Lea, AJ1
Adelstein, AM1
Donovan, JW1
White, GC1
Ruttle, S1
Bär, A1
Biermann, C1
Mann, J1
Hamilton, CL1
Beringer, A1
Pröls, H1
Haslbeck, M1
Mehnert, H2
Guy-Grand, B1
Dorf, G1
Duchier, J1
Aimez, P1

Reviews

5 reviews available for saccharin and Diabetes Mellitus

ArticleYear
Is the Use of Artificial Sweeteners Beneficial for Patients with Diabetes Mellitus? The Advantages and Disadvantages of Artificial Sweeteners.
    Nutrients, 2022, Oct-22, Volume: 14, Issue:21

    Topics: Animals; Aspartame; Cohort Studies; Diabetes Mellitus; Humans; Obesity; Saccharin; Sweetening Agents

2022
Biological fate of low-calorie sweeteners.
    Nutrition reviews, 2016, Volume: 74, Issue:11

    Topics: Animals; Aspartame; Diabetes Mellitus; Diterpenes, Kaurane; Energy Intake; Glucosides; Humans; Legis

2016
Benefits of saccharin: a review.
    Environmental research, 1978, Volume: 15, Issue:1

    Topics: Body Weight; Dental Caries; Diabetes Mellitus; Drug Compounding; Humans; Hyperlipidemias; Obesity; S

1978
[Recent acquisitions on sweetening agents. Applications to the diabetic diet].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1976

    Topics: Amino Acids; Cyclamates; Diabetes Mellitus; Diet, Diabetic; Diterpenes; Flavonoids; Glycyrrhiza; Hum

1976
Dietary advice for diabetics: a perspective from the United Kingdom.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:1

    Topics: Blood Glucose; Diabetes Mellitus; Diabetic Angiopathies; Diet, Sodium-Restricted; Dietary Carbohydra

1986

Trials

1 trial available for saccharin and Diabetes Mellitus

ArticleYear
[Investigations into the action of high doses of saccharin on the metabolism in diabetics (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1973, Oct-12, Volume: 98, Issue:41

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Follow-Up Studies; Glycosuria; Humans; Hypoglycemic Agents;

1973

Other Studies

17 other studies available for saccharin and Diabetes Mellitus

ArticleYear
Insights into the effect of artificial sweeteners on the structure, stability, and fibrillation of type I collagen.
    International journal of biological macromolecules, 2020, Dec-01, Volume: 164

    Topics: Aspartame; Collagen Type I; Diabetes Mellitus; Fibril-Associated Collagens; Humans; Obesity; Sacchar

2020
Glucose regulation is associated with cognitive performance in young nondiabetic adults.
    Behavioural brain research, 2011, Sep-12, Volume: 222, Issue:1

    Topics: Analysis of Variance; Attention; Blood Glucose; Chi-Square Distribution; Cholesterol; Cognition; Dia

2011
Estimated intake of the artificial sweeteners acesulfame-K, aspartame, cyclamate and saccharin in a group of Swedish diabetics.
    Food additives and contaminants, 2003, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aspartame; Beverages; Child; Child, Pr

2003
[Hypoglycemic drugs used in the treatment of saccharin diabetes].
    El Dia medico, 1958, May-22, Volume: 30, Issue:32

    Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Saccharin

1958
Leptin modulates behavioral responses to sweet substances by influencing peripheral taste structures.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Animals; Behavior, Animal; Diabetes Mellitus; Female; Gene Expression; In Situ Hybridization; Leptin

2004
Nasal mucociliary clearance in total laryngectomized patients.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2006, Volume: 263, Issue:12

    Topics: Adult; Diabetes Mellitus; Elasticity; Female; Humans; Laryngectomy; Male; Middle Aged; Mucociliary C

2006
Sweetness in the diabetic diet.
    Diabetologia, 1982, Volume: 23, Issue:3

    Topics: Diabetes Mellitus; Diet, Diabetic; Dietary Carbohydrates; Fructose; Humans; Saccharin; Sorbitol; Swe

1982
[Synthetic sweetening agents: current controversy].
    Diabete & metabolisme, 1978, Volume: 4, Issue:2

    Topics: Animals; Carcinogens; Cyclamates; Diabetes Mellitus; Dose-Response Relationship, Drug; France; Human

1978
Policy statement. Saccharin.
    Diabetes, 1978, Volume: 27, Issue:8

    Topics: Animals; Diabetes Mellitus; Food Additives; Humans; Neoplasms; Research; Saccharin; Societies, Medic

1978
Specially designed sweeteners and food for diabetics--a real need?
    The American journal of clinical nutrition, 1976, Volume: 29, Issue:7

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Dietary Carbohydrates; Evaluation Studies as

1976
Cancer mortality and saccharin consumption in diabetics.
    British journal of preventive & social medicine, 1976, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Aged; Coronary Disease; Diabetes Complications; Diabetes Mellitus; England; Fema

1976
Intake of intense sweeteners in Germany.
    Zeitschrift fur Ernahrungswissenschaft, 1992, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Aspartame; Beverages; Child; Child, Preschool; Cholesterol, Dietary; Cyclamates;

1992
Sweetener intakes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Aspartame; Beverages; Child; Child, Preschool; Diabetes Mellitus; Humans; M

1991
An observation of long-term experimental obesity and diabetes mellitus in the monkey.
    Journal of medical primatology, 1972, Volume: 1, Issue:4

    Topics: Adipose Tissue; Animals; Blood Glucose; Diabetes Mellitus; Diet; Fructose; Glycosuria; Hypothalamus;

1972
[Are sweetening substances dangerous for diabetics?].
    Wiener medizinische Wochenschrift (1946), 1973, Jan-27, Volume: 123, Issue:4

    Topics: Cyclamates; Diabetes Mellitus; Diet, Diabetic; Drug Combinations; Humans; Liver; Liver Glycogen; Sac

1973
[Dietetics and nutrition in 1972].
    La Revue du praticien, 1972, Feb-21, Volume: 22, Issue:6

    Topics: Adipose Tissue; Alcoholic Intoxication; Anorexia Nervosa; Caffeine; Calcium; Catecholamines; Coffee;

1972
[Synthetic sweetening agents].
    Deutsche medizinische Wochenschrift (1946), 1971, Oct-29, Volume: 96, Issue:44

    Topics: Cyclamates; Diabetes Mellitus; Diet; Humans; Saccharin; Sweetening Agents

1971