saccharin has been researched along with Diabetes Mellitus, Type 2 in 9 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin, a frontline therapy for type 2 diabetes and related metabolic diseases, results in variable outcomes." | 1.91 | Non-Nutritive Sweetened Beverages Impair Therapeutic Benefits of Metformin in Prediabetic Diet-Induced Obese Mice. ( Bernier, A; de Lartigue, G; Rourk, K; Singh, A, 2023) |
| "Morbidity and mortality attributed to type 2 diabetes have exponentially increased in the US." | 1.56 | Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model. ( Nazarian, A; O'Dell, LE; Richardson, JR, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, W | 1 |
| Cao, H | 1 |
| Xu, Y | 1 |
| Ren, Y | 1 |
| Rao, L | 1 |
| Shao, X | 1 |
| Chen, H | 1 |
| Wu, L | 1 |
| Liu, J | 1 |
| Su, C | 1 |
| Peng, C | 1 |
| Huang, Y | 1 |
| Wan, J | 1 |
| Hasan, HM | 1 |
| Alkass, SY | 1 |
| de Oliveira, DSP | 1 |
| Singh, A | 1 |
| Rourk, K | 1 |
| Bernier, A | 1 |
| de Lartigue, G | 1 |
| Richardson, JR | 1 |
| O'Dell, LE | 1 |
| Nazarian, A | 1 |
| Mchunu, N | 1 |
| Chukwuma, CI | 1 |
| Ibrahim, MA | 1 |
| Oyebode, OA | 1 |
| Dlamini, SN | 1 |
| Islam, MS | 1 |
| Khan, SA | 1 |
| Bailey, CJ | 1 |
| Day, C | 1 |
| Knapper, JM | 1 |
| Turner, SL | 1 |
| Flatt, PR | 1 |
| Cooper, PL | 1 |
| Wahlqvist, ML | 1 |
| Simpson, RW | 1 |
| Horwitz, DL | 1 |
| McLane, M | 1 |
| Kobe, P | 1 |
1 review available for saccharin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Artificial sweeteners: safe or unsafe?
Topics: Aspartame; Diabetes Mellitus, Type 2; Dipeptides; Humans; Neoplasms; Obesity; Saccharin; Sucrose; Sw | 2015 |
2 trials available for saccharin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Sucrose versus saccharin as an added sweetener in non-insulin-dependent diabetes: short- and medium-term metabolic effects.
Topics: Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Diet, Diabetic; Dietary Carbo | 1988 |
Response to single dose of aspartame or saccharin by NIDDM patients.
Topics: Adult; Aspartame; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Female; Glucagon; Humans; In | 1988 |
6 other studies available for saccharin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Topics: Cysteine; Diabetes Mellitus, Type 2; Glucose; Humans; Saccharin | 2022 |
Impact of Long-Term Cyclamate and Saccharin Consumption on Biochemical Parameters in Healthy Individuals and Type 2 Diabetes Mellitus Patients.
Topics: Animals; Ceruloplasmin; Cyclamates; Diabetes Mellitus, Type 2; Humans; Saccharin; Sweetening Agents | 2023 |
Non-Nutritive Sweetened Beverages Impair Therapeutic Benefits of Metformin in Prediabetic Diet-Induced Obese Mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucose Intolerance; High Fructose Corn Syrup; M | 2023 |
Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model.
Topics: Animals; Conditioning, Psychological; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nicot | 2020 |
Commercially available non-nutritive sweeteners modulate the antioxidant status of type 2 diabetic rats.
Topics: Animals; Antioxidants; Aspartame; Catalase; Diabetes Mellitus, Type 2; Glutathione; Glutathione Redu | 2019 |
Antihyperglycaemic effect of saccharin in diabetic ob/ob mice.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Homeostasis; | 1997 |