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saccharin and Delayed Effects, Prenatal Exposure

saccharin has been researched along with Delayed Effects, Prenatal Exposure in 23 studies

Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.

Research Excerpts

ExcerptRelevanceReference
"The neurobiological basis of memory deficits after prenatal alcohol exposure (PAE) is often linked to structural and functional alterations in the medial temporal lobe, including the hippocampus."1.51Moderate prenatal alcohol exposure impairs performance by adult male rats in an object-place paired-associate task. ( Clark, BJ; Davies, S; Goss, J; Hamilton, DA; Sanchez, LM; Savage, DD; Wagner, J, 2019)
"Vinclozolin is a fungicide used on food crops with human exposure estimated at approximately 2 microg/kg/day from ingestion; occupational exposure, however, may be greater."1.31Behavioral responses of rats exposed to long-term dietary vinclozolin. ( Delclos, KB; Ferguson, SA; Flynn, KM; Newbold, RR, 2001)
"Saccharin preference was then examined in separate groups of adult males that received either a 0."1.29Gender and intrauterine position influence saccharin preference in mice. ( Bushong, ME; Mann, MA, 1994)
"Body weights were significantly depressed in NaS-treated litters by 4 days after birth, and were 35% lower than controls by 30 days when the animals were killed."1.28Effects of in utero and postnatal sodium saccharin exposure on the nutritional status of the young rat. I. Effects at 30 days post-birth. ( Cohen, SM; Ellwein, LB; Garland, EM; Khachab, M; Kraft, PL; Patil, K; Shapiro, R, 1991)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19909 (39.13)18.7374
1990's6 (26.09)18.2507
2000's3 (13.04)29.6817
2010's3 (13.04)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Ascencio Gutierrez, V1
Carrillo, AA1
Boersma, GJ1
Tamashiro, KLK1
Moran, TH1
Iñiguez, SD1
Treesukosol, Y1
Godoi, AR1
Fioravante, VC1
Santos, BM1
Martinez, FE1
Pinheiro, PFF1
Sanchez, LM1
Goss, J1
Wagner, J1
Davies, S1
Savage, DD2
Hamilton, DA2
Clark, BJ1
Gore-Langton, JK1
Spear, LP1
Candelaria-Cook, FT1
Akers, KG1
Rice, JP1
Maes, LI1
Rosenberg, M1
Valenzuela, CF1
Ikeda, M1
Mitsui, T1
Setani, K1
Tamura, M1
Kakeyama, M1
Sone, H1
Tohyama, C1
Tomita, T1
Riley, EP1
Barron, S1
Driscoll, CD1
Chen, JS1
Martin, JC1
Martin, DC1
Sigman, G1
Day-Pfeiffer, H1
McGivern, RF3
Clancy, AN1
Hill, MA1
Noble, EP1
Jensen, OM1
Kamby, C1
Keshet, GI1
Weinstock, M1
Bushong, ME1
Mann, MA1
Gagin, R1
Cohen, E1
Shavit, Y1
Mickley, GA1
Remmers-Roeber, DR1
Dengler, CM1
Kenmuir, CL1
Crouse, C1
Flynn, KM1
Delclos, KB1
Newbold, RR1
Ferguson, SA1
Gorczynski, RM1
Garland, EM2
Kraft, PL2
Shapiro, R2
Khachab, M1
Patil, K1
Ellwein, LB1
Cohen, SM2
Mattson, BJ1
Parr, JM1
Nabors, LO1
Holcomb, C1
Poland, RE2
Taylor, AN1
Branch, BJ1
Raum, WJ1
Finger, S1
Almli, CR1
Green, L1
Wolf, C1
Morgane, PJ1
Lichtensteiger, W1
Schlumpf, M1

Other Studies

23 other studies available for saccharin and Delayed Effects, Prenatal Exposure

ArticleYear
Effect of early-life stress or fluoxetine exposure on later-life conditioned taste aversion learning in Sprague-Dawley rats.
    Neuroscience letters, 2022, 09-14, Volume: 787

    Topics: Animals; Avoidance Learning; Body Weight; Female; Fluoxetine; Lithium Chloride; Male; Prenatal Expos

2022
Maternal exposure of rats to sodium saccharin during gestation and lactation on male offspring†.
    Biology of reproduction, 2023, 01-14, Volume: 108, Issue:1

    Topics: Animals; Estradiol; Female; Humans; Lactation; Male; Maternal Exposure; Pregnancy; Prenatal Exposure

2023
Moderate prenatal alcohol exposure impairs performance by adult male rats in an object-place paired-associate task.
    Behavioural brain research, 2019, 03-15, Volume: 360

    Topics: Analysis of Variance; Animals; Discrimination, Psychological; Disease Models, Animal; Ethanol; Femal

2019
Prenatal ethanol exposure attenuates sensitivity to the aversive effects of ethanol in adolescence and increases adult preference for a 5% ethanol solution in males, but not females.
    Alcohol (Fayetteville, N.Y.), 2019, Volume: 79

    Topics: Age Factors; Alcohol Drinking; Animals; Avoidance Learning; Central Nervous System Depressants; Cond

2019
Patterns of social-experience-related c-fos and Arc expression in the frontal cortices of rats exposed to saccharin or moderate levels of ethanol during prenatal brain development.
    Behavioural brain research, 2010, Dec-06, Volume: 214, Issue:1

    Topics: Animals; Cerebral Cortex; Cytoskeletal Proteins; Ethanol; Female; Gene Expression Regulation, Develo

2010
In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats disrupts brain sexual differentiation.
    Toxicology and applied pharmacology, 2005, May-15, Volume: 205, Issue:1

    Topics: Administration, Oral; Aging; Animals; Animals, Newborn; Animals, Suckling; Aromatase; Brain; Brain C

2005
Taste aversion learning in preweanling rats exposed to alcohol prenatally.
    Teratology, 1984, Volume: 29, Issue:3

    Topics: Animals; Animals, Newborn; Avoidance Learning; Chlorides; Conditioning, Psychological; Ethanol; Fema

1984
Saccharin preferences in food deprived aging rats are altered as a function of perinatal drug exposure.
    Physiology & behavior, 1983, Volume: 30, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Body Weight; Drinking; Female; Fetus; Food Deprivation; Food P

1983
Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat.
    Science (New York, N.Y.), 1984, May-25, Volume: 224, Issue:4651

    Topics: Age Factors; Animals; Discrimination Learning; Ethanol; Female; Food Preferences; Gestational Age; M

1984
Intra-uterine exposure to saccharin and risk of bladder cancer in man.
    International journal of cancer, 1982, May-15, Volume: 29, Issue:5

    Topics: Adult; Denmark; Female; Humans; Male; Pregnancy; Prenatal Exposure Delayed Effects; Risk; Saccharin;

1982
Maternal naltrexone prevents morphological and behavioral alterations induced in rats by prenatal stress.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:3

    Topics: Animals; Choice Behavior; Female; Infusion Pumps, Implantable; Male; Maze Learning; Naltrexone; Narc

1995
Gender and intrauterine position influence saccharin preference in mice.
    Hormones and behavior, 1994, Volume: 28, Issue:3

    Topics: Animals; Appetite; Dose-Response Relationship, Drug; Female; Food Preferences; Gonadal Steroid Hormo

1994
Prenatal exposure to morphine alters analgesic responses and preference for sweet solutions in adult rats.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:4

    Topics: Analgesics, Opioid; Animals; Delayed-Action Preparations; Female; Food Preferences; Male; Morphine;

1996
Paradoxical effects of ketamine on the memory of fetuses of different ages.
    Brain research. Developmental brain research, 2001, Mar-29, Volume: 127, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Antimanic Agents; Avoidance Learning; Brain; Critical Period

2001
Behavioral responses of rats exposed to long-term dietary vinclozolin.
    Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:3

    Topics: Administration, Oral; Animal Feed; Animals; Behavior, Animal; Body Weight; Drinking Behavior; Female

2001
Conditioned stress responses by pregnant and/or lactating mice reduce immune responses of their offspring after weaning.
    Brain, behavior, and immunity, 1992, Volume: 6, Issue:1

    Topics: Animals; Conditioning, Classical; Female; Immunity, Maternally-Acquired; Immunologic Deficiency Synd

1992
Effects of in utero and postnatal sodium saccharin exposure on the nutritional status of the young rat. I. Effects at 30 days post-birth.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:10

    Topics: Animals; Body Weight; Female; Liver; Male; Nutritional Status; Pregnancy; Prenatal Exposure Delayed

1991
Effects of in utero and postnatal sodium saccharin exposure on the nutritional status of the young rat. II. Dose response and reversibility.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:10

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Folic Acid; Liver; Male; Nutritional

1991
Saccharin and aspartame: are they safe to consume during pregnancy?
    The Journal of reproductive medicine, 1988, Volume: 33, Issue:8

    Topics: Adult; Animals; Aspartame; Dipeptides; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy

1988
Effects of prenatal testosterone propionate treatment on saccharin preference of adult rats exposed to ethanol in utero.
    Physiology & behavior, 1987, Volume: 39, Issue:2

    Topics: Animals; Eating; Ethanol; Female; Food Preferences; Male; Osmolar Concentration; Pregnancy; Prenatal

1987
Prenatal stress feminizes adult male saccharin preference and maze learning: antagonism by propranolol.
    Monographs in neural sciences, 1986, Volume: 12

    Topics: Animals; Disorders of Sex Development; Female; Food Preferences; Learning; Male; Pregnancy; Pregnanc

1986
Severe early malnutrition and DRL performance in the rat.
    Physiology & behavior, 1986, Volume: 38, Issue:5

    Topics: Animals; Conditioning, Operant; Discrimination Learning; Efficiency; Female; Male; Pregnancy; Pregna

1986
Prenatal nicotine affects fetal testosterone and sexual dimorphism of saccharin preference.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:3

    Topics: Animals; Choice Behavior; Female; Fetus; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rat

1985