saccharin has been researched along with Ciliary Motility Disorders in 12 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Ciliary Motility Disorders: Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. Abnormal ciliary beating is likely due to defects in any of the 200 plus ciliary proteins, such as missing motor enzyme DYNEIN arms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to evaluate the clinical value of the saccharin test as a practical and simple measure of mucociliary clearance, nasal mucociliary clearance (NMCC) and ciliary ultrastructure were studied in 22 patients suspected of having primary ciliary dyskinesia (PCD) based on the saccharin test." | 7.67 | The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia. ( Barlocco, EG; Canciani, M; de Santi, MM; Gardi, C; Lungarella, G; Mastella, G, 1988) |
| "In order to evaluate the clinical value of the saccharin test as a practical and simple measure of mucociliary clearance, nasal mucociliary clearance (NMCC) and ciliary ultrastructure were studied in 22 patients suspected of having primary ciliary dyskinesia (PCD) based on the saccharin test." | 3.67 | The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia. ( Barlocco, EG; Canciani, M; de Santi, MM; Gardi, C; Lungarella, G; Mastella, G, 1988) |
| "Bronchiectasis is a common condition among the Oriental population and affected patients suffer from chronic sputum production punctuated by recurrent infective exacerbations." | 2.41 | Ciliary assessment in bronchiectasis. ( Tipoe, G; Tsang, KW; Zheng, L, 2000) |
| "Primary ciliary dyskinesia (PCD) is an inherited condition characterised by functional and/or structural congenital abnormalities of cilia." | 2.41 | Primary ciliary dyskinesia. ( Bush, A, 2000) |
| "A case of immotile cilia syndrome (ICS) is presented." | 2.38 | [A case of immotile cilia syndrome and a review of Japanese cases]. ( Kamo, T; Kawai, T; Nogawa, S; Onaka, A; Torikata, C; Toyoda, T, 1989) |
| "Primary ciliary dyskinesia (PCD) is usually diagnosed by ultrastructural investigations of nasal or bronchial mucosa." | 1.30 | [Diagnostic procedure in primary ciliary dyskinesia]. ( Hafner, B; Mann, W; Maurer, J; Riechelmann, H, 1999) |
| "The Saccharin test is a non-dangerous, inexpensive, suitable and repeatable method for assessing the mucociliary function of the respiratory epithelium." | 1.28 | [The saccharin test in the pediatric broncho-pneumonologic outpatient clinic. A noninvasive screening method for the assessment of ciliary function of the respiratory tract in children]. ( Adler, S; Ballke, EH; Bruns, R; Klingbeil, P; Wiersbitzky, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stanley, P | 1 |
| MacWilliam, L | 1 |
| Greenstone, M | 1 |
| Mackay, I | 1 |
| Cole, P | 1 |
| Kleinschmidt, EG | 1 |
| Witt, G | 1 |
| Loukides, S | 1 |
| Kharitonov, S | 1 |
| Wodehouse, T | 1 |
| Cole, PJ | 1 |
| Barnes, PJ | 1 |
| Riechelmann, H | 1 |
| Hafner, B | 1 |
| Maurer, J | 1 |
| Mann, W | 1 |
| Tsang, KW | 1 |
| Zheng, L | 1 |
| Tipoe, G | 1 |
| Bush, A | 1 |
| Mladina, R | 1 |
| Gjurić, M | 1 |
| Klingbeil, P | 1 |
| Wiersbitzky, S | 1 |
| Bruns, R | 1 |
| Ballke, EH | 1 |
| Adler, S | 1 |
| Nogawa, S | 1 |
| Toyoda, T | 1 |
| Kamo, T | 1 |
| Onaka, A | 1 |
| Kawai, T | 1 |
| Torikata, C | 1 |
| Canciani, M | 1 |
| Barlocco, EG | 1 |
| Mastella, G | 1 |
| de Santi, MM | 1 |
| Gardi, C | 1 |
| Lungarella, G | 1 |
| Reiche, K | 1 |
| Winkler, U | 1 |
| Deitmer, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Pulmonary Rehabilitation on Secretion Transport, Inflammation and Respiratory System Strength and Quality of Life in Patients With Bronchiectasis[NCT02823587] | 60 participants (Anticipated) | Interventional | 2016-07-31 | Recruiting | |||
| A Single-center, Non-randomized, Open, Single-arm Confirmatory Clinical Study to Evaluate the Safety and Efficacy of Platelet Rich Plasma Injection for Patients With Atrophic Rhinitis[NCT03112330] | 22 participants (Actual) | Interventional | 2017-06-08 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for saccharin and Ciliary Motility Disorders
| Article | Year |
|---|---|
Ciliary assessment in bronchiectasis.
Topics: Bronchiectasis; Cilia; Ciliary Motility Disorders; Humans; Microscopy; Microscopy, Electron; Movemen | 2000 |
Primary ciliary dyskinesia.
Topics: Child; Child, Preschool; Ciliary Motility Disorders; Female; Hearing Disorders; Humans; Infant, Newb | 2000 |
[A case of immotile cilia syndrome and a review of Japanese cases].
Topics: Adult; Cilia; Ciliary Motility Disorders; Humans; Male; Microscopy, Electron, Scanning; Mucociliary | 1989 |
1 trial available for saccharin and Ciliary Motility Disorders
| Article | Year |
|---|---|
Effect of arginine on mucociliary function in primary ciliary dyskinesia.
Topics: Administration, Intranasal; Adult; Arginine; Blood Pressure; Cilia; Ciliary Motility Disorders; Doub | 1998 |
8 other studies available for saccharin and Ciliary Motility Disorders
| Article | Year |
|---|---|
Efficacy of a saccharin test for screening to detect abnormal mucociliary clearance.
Topics: Cilia; Ciliary Motility Disorders; Humans; Nasal Mucosa; Saccharin; Time Factors | 1984 |
[Evaluation of nasal mucociliary clearance with a modified saccharin test].
Topics: Adolescent; Adult; Aged; Ciliary Motility Disorders; Female; Humans; Male; Middle Aged; Mucociliary | 1995 |
[Diagnostic procedure in primary ciliary dyskinesia].
Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Ciliary Motility Disorders; Diagnosis, Different | 1999 |
[The saccharin test in comparison with cytologic findings in assessing nasal mucosa function].
Topics: Adult; Biopsy; Ciliary Motility Disorders; Female; Humans; Male; Nasal Mucosa; Reference Values; Sac | 1990 |
[The saccharin test in the pediatric broncho-pneumonologic outpatient clinic. A noninvasive screening method for the assessment of ciliary function of the respiratory tract in children].
Topics: Adolescent; Biological Transport; Child; Child, Preschool; Cilia; Ciliary Motility Disorders; Diagno | 1990 |
The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia.
Topics: Adolescent; Adult; Child; Child, Preschool; Cilia; Ciliary Motility Disorders; Epithelium; False Neg | 1988 |
[Mucociliary clearance of the nasal mucosa--a functional diagnostic method for occupational medicine problems].
Topics: Adult; Ciliary Motility Disorders; Female; Gentian Violet; Humans; Male; Occupational Diseases; Sacc | 1987 |
A modification of the saccharine test for nasal mucociliary clearance.
Topics: Animals; Anion Exchange Resins; Chronic Disease; Ciliary Motility Disorders; Common Cold; Dogs; Huma | 1986 |