Page last updated: 2024-11-04

saccharin and Ciliary Dyskinesia

saccharin has been researched along with Ciliary Dyskinesia in 12 studies

Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.

Research Excerpts

ExcerptRelevanceReference
"In order to evaluate the clinical value of the saccharin test as a practical and simple measure of mucociliary clearance, nasal mucociliary clearance (NMCC) and ciliary ultrastructure were studied in 22 patients suspected of having primary ciliary dyskinesia (PCD) based on the saccharin test."7.67The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia. ( Barlocco, EG; Canciani, M; de Santi, MM; Gardi, C; Lungarella, G; Mastella, G, 1988)
"In order to evaluate the clinical value of the saccharin test as a practical and simple measure of mucociliary clearance, nasal mucociliary clearance (NMCC) and ciliary ultrastructure were studied in 22 patients suspected of having primary ciliary dyskinesia (PCD) based on the saccharin test."3.67The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia. ( Barlocco, EG; Canciani, M; de Santi, MM; Gardi, C; Lungarella, G; Mastella, G, 1988)
"Bronchiectasis is a common condition among the Oriental population and affected patients suffer from chronic sputum production punctuated by recurrent infective exacerbations."2.41Ciliary assessment in bronchiectasis. ( Tipoe, G; Tsang, KW; Zheng, L, 2000)
"Primary ciliary dyskinesia (PCD) is an inherited condition characterised by functional and/or structural congenital abnormalities of cilia."2.41Primary ciliary dyskinesia. ( Bush, A, 2000)
"A case of immotile cilia syndrome (ICS) is presented."2.38[A case of immotile cilia syndrome and a review of Japanese cases]. ( Kamo, T; Kawai, T; Nogawa, S; Onaka, A; Torikata, C; Toyoda, T, 1989)
"Primary ciliary dyskinesia (PCD) is usually diagnosed by ultrastructural investigations of nasal or bronchial mucosa."1.30[Diagnostic procedure in primary ciliary dyskinesia]. ( Hafner, B; Mann, W; Maurer, J; Riechelmann, H, 1999)
"The Saccharin test is a non-dangerous, inexpensive, suitable and repeatable method for assessing the mucociliary function of the respiratory epithelium."1.28[The saccharin test in the pediatric broncho-pneumonologic outpatient clinic. A noninvasive screening method for the assessment of ciliary function of the respiratory tract in children]. ( Adler, S; Ballke, EH; Bruns, R; Klingbeil, P; Wiersbitzky, S, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stanley, P1
MacWilliam, L1
Greenstone, M1
Mackay, I1
Cole, P1
Kleinschmidt, EG1
Witt, G1
Loukides, S1
Kharitonov, S1
Wodehouse, T1
Cole, PJ1
Barnes, PJ1
Riechelmann, H1
Hafner, B1
Maurer, J1
Mann, W1
Tsang, KW1
Zheng, L1
Tipoe, G1
Bush, A1
Mladina, R1
Gjurić, M1
Klingbeil, P1
Wiersbitzky, S1
Bruns, R1
Ballke, EH1
Adler, S1
Nogawa, S1
Toyoda, T1
Kamo, T1
Onaka, A1
Kawai, T1
Torikata, C1
Canciani, M1
Barlocco, EG1
Mastella, G1
de Santi, MM1
Gardi, C1
Lungarella, G1
Reiche, K1
Winkler, U1
Deitmer, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Pulmonary Rehabilitation on Secretion Transport, Inflammation and Respiratory System Strength and Quality of Life in Patients With Bronchiectasis[NCT02823587]60 participants (Anticipated)Interventional2016-07-31Recruiting
A Single-center, Non-randomized, Open, Single-arm Confirmatory Clinical Study to Evaluate the Safety and Efficacy of Platelet Rich Plasma Injection for Patients With Atrophic Rhinitis[NCT03112330]22 participants (Actual)Interventional2017-06-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for saccharin and Ciliary Dyskinesia

ArticleYear
Ciliary assessment in bronchiectasis.
    Respirology (Carlton, Vic.), 2000, Volume: 5, Issue:2

    Topics: Bronchiectasis; Cilia; Ciliary Motility Disorders; Humans; Microscopy; Microscopy, Electron; Movemen

2000
Primary ciliary dyskinesia.
    Acta oto-rhino-laryngologica Belgica, 2000, Volume: 54, Issue:3

    Topics: Child; Child, Preschool; Ciliary Motility Disorders; Female; Hearing Disorders; Humans; Infant, Newb

2000
[A case of immotile cilia syndrome and a review of Japanese cases].
    Nihon Kyobu Shikkan Gakkai zasshi, 1989, Volume: 27, Issue:4

    Topics: Adult; Cilia; Ciliary Motility Disorders; Humans; Male; Microscopy, Electron, Scanning; Mucociliary

1989

Trials

1 trial available for saccharin and Ciliary Dyskinesia

ArticleYear
Effect of arginine on mucociliary function in primary ciliary dyskinesia.
    Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125

    Topics: Administration, Intranasal; Adult; Arginine; Blood Pressure; Cilia; Ciliary Motility Disorders; Doub

1998

Other Studies

8 other studies available for saccharin and Ciliary Dyskinesia

ArticleYear
Efficacy of a saccharin test for screening to detect abnormal mucociliary clearance.
    British journal of diseases of the chest, 1984, Volume: 78, Issue:1

    Topics: Cilia; Ciliary Motility Disorders; Humans; Nasal Mucosa; Saccharin; Time Factors

1984
[Evaluation of nasal mucociliary clearance with a modified saccharin test].
    Laryngo- rhino- otologie, 1995, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Aged; Ciliary Motility Disorders; Female; Humans; Male; Middle Aged; Mucociliary

1995
[Diagnostic procedure in primary ciliary dyskinesia].
    Laryngo- rhino- otologie, 1999, Volume: 78, Issue:4

    Topics: Adolescent; Adult; Biopsy; Child; Child, Preschool; Ciliary Motility Disorders; Diagnosis, Different

1999
[The saccharin test in comparison with cytologic findings in assessing nasal mucosa function].
    HNO, 1990, Volume: 38, Issue:3

    Topics: Adult; Biopsy; Ciliary Motility Disorders; Female; Humans; Male; Nasal Mucosa; Reference Values; Sac

1990
[The saccharin test in the pediatric broncho-pneumonologic outpatient clinic. A noninvasive screening method for the assessment of ciliary function of the respiratory tract in children].
    Kinderarztliche Praxis, 1990, Volume: 58, Issue:4

    Topics: Adolescent; Biological Transport; Child; Child, Preschool; Cilia; Ciliary Motility Disorders; Diagno

1990
The saccharin method for testing mucociliary function in patients suspected of having primary ciliary dyskinesia.
    Pediatric pulmonology, 1988, Volume: 5, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Cilia; Ciliary Motility Disorders; Epithelium; False Neg

1988
[Mucociliary clearance of the nasal mucosa--a functional diagnostic method for occupational medicine problems].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1987, Volume: 33, Issue:5

    Topics: Adult; Ciliary Motility Disorders; Female; Gentian Violet; Humans; Male; Occupational Diseases; Sacc

1987
A modification of the saccharine test for nasal mucociliary clearance.
    Rhinology, 1986, Volume: 24, Issue:4

    Topics: Animals; Anion Exchange Resins; Chronic Disease; Ciliary Motility Disorders; Common Cold; Dogs; Huma

1986