saccharin has been researched along with Carcinoma, Papillary in 5 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Carcinoma, Papillary: A malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " None of the incidences or numbers of these lesions were significantly different in any of the other saccharin-treated groups when compared to the group treated with BBN alone except for the incidences of two types of hyperplasias in the female rats dosed with 10,000 ppm saccharin." | 5.26 | Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Hagiwara, A; Imaida, K; Ito, N; Nakanishi, K; Shibata, M; Tatematsu, M, 1980) |
| " None of the incidences or numbers of these lesions were significantly different in any of the other saccharin-treated groups when compared to the group treated with BBN alone except for the incidences of two types of hyperplasias in the female rats dosed with 10,000 ppm saccharin." | 1.26 | Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine. ( Hagiwara, A; Imaida, K; Ito, N; Nakanishi, K; Shibata, M; Tatematsu, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakanishi, K | 1 |
| Hagiwara, A | 1 |
| Shibata, M | 1 |
| Imaida, K | 1 |
| Tatematsu, M | 1 |
| Ito, N | 1 |
| Cook, CE | 1 |
| Oser, BL | 1 |
| Crampton, RF | 1 |
| Bryan, GT | 1 |
| Yoshida, O | 1 |
3 reviews available for saccharin and Carcinoma, Papillary
| Article | Year |
|---|---|
Cyclamates: a review of the current position.
Topics: Animals; Carcinogens; Carcinoma, Papillary; Cyclamates; Cyclohexylamines; Diabetes Mellitus, Type 1; | 1975 |
Problems of food additives, with special reference to cyclamates.
Topics: Animals; Bromine; Carcinoma, Papillary; Cyclamates; Food Additives; Food Contamination; Food-Process | 1970 |
Artificial sweeteners as urinary bladder carcinogens.
Topics: Administration, Oral; Animals; Carcinogens; Carcinoma; Carcinoma, Papillary; Cattle; Cricetinae; Cyc | 1971 |
2 other studies available for saccharin and Carcinoma, Papillary
| Article | Year |
|---|---|
Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Dose-Response Relationship, Drug; Femal | 1980 |
FDRL investigation of cyclamates.
Topics: Animals; Carcinoma, Papillary; Cyclamates; Cyclohexylamines; Female; Male; Mice; Rats; Saccharin; Un | 1975 |