saccharin has been researched along with Bladder Diseases in 10 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ulceration of the bladder, induced by cyclophosphamide (CP) or freezing, followed by sodium saccharin in the diet results in the induction of bladder cancer." | 7.67 | Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin. ( Cohen, SM; Hasegawa, R; Murasaki, G; Suzuki, T, 1984) |
| " Ulceration of the bladder, induced by cyclophosphamide (CP) or freezing, followed by sodium saccharin in the diet results in the induction of bladder cancer." | 3.67 | Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin. ( Cohen, SM; Hasegawa, R; Murasaki, G; Suzuki, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasegawa, R | 2 |
| St John, MK | 1 |
| Cano, M | 1 |
| Issenberg, P | 1 |
| Klein, DA | 1 |
| Walker, BA | 1 |
| Jones, JW | 1 |
| Schnell, RC | 1 |
| Merrick, BA | 1 |
| Davies, MH | 1 |
| Suzuki, T | 1 |
| Murasaki, G | 5 |
| Cohen, SM | 6 |
| Greenfield, RE | 1 |
| Taylor, JM | 1 |
| Weinberger, MA | 1 |
| Friedman, L | 1 |
| Chappel, CI | 1 |
| Bryan, GT | 1 |
| Yoshida, O | 1 |
2 reviews available for saccharin and Bladder Diseases
| Article | Year |
|---|---|
A review and biological risk assessment of sodium saccharin.
Topics: Animals; Humans; Hydrogen-Ion Concentration; Male; Rats; Risk; Saccharin; Sodium; Urinary Bladder; U | 1992 |
Artificial sweeteners as urinary bladder carcinogens.
Topics: Administration, Oral; Animals; Carcinogens; Carcinoma; Carcinoma, Papillary; Cattle; Cricetinae; Cyc | 1971 |
8 other studies available for saccharin and Bladder Diseases
| Article | Year |
|---|---|
Bladder freeze ulceration and sodium saccharin feeding in the rat: examination for urinary nitrosamines, mutagens and bacteria, and effects on hepatic microsomal enzymes.
Topics: Administration, Oral; Aniline Hydroxylase; Animals; Body Weight; Calcium; Carcinogens; Cytochrome P- | 1984 |
Distinction by concanavalin A agglutination between ulceration and repair of rat bladder epithelium induced by freezing or cyclophosphamide and the effect of sodium saccharin.
Topics: Agglutination; Animals; Carcinogens; Concanavalin A; Cyclophosphamide; Dose-Response Relationship, D | 1984 |
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder.
Topics: Animals; Cocarcinogenesis; Diet; FANFT; Growth; Male; Neoplasms, Experimental; Rats; Saccharin; Thia | 1983 |
Effect of sodium saccharin on urinary bladder epithelial regenerative hyperplasia following freeze ulceration.
Topics: Animals; Autoradiography; Cell Division; Freezing; Hyperplasia; Male; Microscopy, Electron, Scanning | 1983 |
Promotion in urinary bladder carcinogenesis.
Topics: Animals; Cell Division; Cocarcinogenesis; FANFT; Neoplasms, Experimental; Rats; Saccharin; Ulcer; Ur | 1983 |
Alterations in the rat kidney associated with sodium saccharin feeding.
Topics: Animals; Body Weight; Cyclophosphamide; Kidney Diseases; Male; Neoplasms; Rats; Rats, Inbred F344; S | 1982 |
Chronic toxicity and carcinogenicity to the urinary bladder of sodium saccharin in the in utero-exposed rat.
Topics: Animals; Body Weight; Carcinogens; Eating; Female; Maternal-Fetal Exchange; Organ Size; Pregnancy; R | 1980 |
Effect of dose of sodium saccharin on the induction of rat urinary bladder proliferation.
Topics: Animals; Dose-Response Relationship, Drug; Hyperplasia; Male; Microscopy, Electron, Scanning; Rats; | 1981 |