saccharin has been researched along with Anhedonia in 7 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asenapine is indicated for the treatment of schizophrenia and manic episodes in bipolar disorder (BPD)." | 3.81 | The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors. ( Einat, H; Ene, HM; Kara, NZ, 2015) |
| " Saccharin-based anhedonia and maternal aggression were increased and lactation was also impaired on day 16 of lactation." | 3.81 | Social stress during lactation, depressed maternal care, and neuropeptidergic gene expression. ( Babb, JA; Bradburn, S; Carini, LM; Murgatroyd, CA; Nephew, BC; Taliefar, M, 2015) |
| " The 2-bottle saccharin preference test for anhedonia revealed that dietary ZS also did not improve depression-like behaviors." | 3.78 | Use of zinc as a treatment for traumatic brain injury in the rat: effects on cognitive and behavioral outcomes. ( Cope, EC; Levenson, CW; Morris, DR; Scrimgeour, AG, 2012) |
| " Our results indicate that intermittent and daily SDS procedures attenuated body weight gain, induced adrenal hypertrophy, and reduced the preference for saccharin, a sweet solution preferred by normal rats." | 3.77 | 5-HT1B mRNA expression after chronic social stress. ( Furay, AR; McDevitt, RA; Miczek, KA; Neumaier, JF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spierling, SR | 1 |
| Mattock, M | 1 |
| Zorrilla, EP | 1 |
| Ene, HM | 1 |
| Kara, NZ | 1 |
| Einat, H | 1 |
| Murgatroyd, CA | 1 |
| Taliefar, M | 1 |
| Bradburn, S | 1 |
| Carini, LM | 1 |
| Babb, JA | 1 |
| Nephew, BC | 1 |
| Shoval, G | 1 |
| Shbiro, L | 1 |
| Hershkovitz, L | 1 |
| Hazut, N | 1 |
| Zalsman, G | 1 |
| Mechoulam, R | 1 |
| Weller, A | 1 |
| Furay, AR | 1 |
| McDevitt, RA | 1 |
| Miczek, KA | 1 |
| Neumaier, JF | 1 |
| Cope, EC | 1 |
| Morris, DR | 1 |
| Scrimgeour, AG | 1 |
| Levenson, CW | 1 |
| Horovitz, O | 1 |
| Tsoory, MM | 1 |
| Yovell, Y | 1 |
| Richter-Levin, G | 1 |
7 other studies available for saccharin and Anhedonia
| Article | Year |
|---|---|
Modeling hypohedonia following repeated social defeat: Individual vulnerability and dopaminergic involvement.
Topics: Amphetamine; Anhedonia; Animals; Choice Behavior; Dominance-Subordination; Dopamine; Dopamine Uptake | 2017 |
The effects of the atypical antipsychotic asenapine in a strain-specific battery of tests for mania-like behaviors.
Topics: Akathisia, Drug-Induced; Amphetamine; Anhedonia; Animals; Antimanic Agents; Antipsychotic Agents; Ap | 2015 |
Social stress during lactation, depressed maternal care, and neuropeptidergic gene expression.
Topics: Aggression; Anhedonia; Animals; Anxiety Disorders; Brain; Chronic Disease; Depression, Postpartum; D | 2015 |
Prohedonic Effect of Cannabidiol in a Rat Model of Depression.
Topics: Analysis of Variance; Anhedonia; Animals; Antidepressive Agents; Anxiety; Cannabidiol; Depressive Di | 2016 |
5-HT1B mRNA expression after chronic social stress.
Topics: Adrenal Glands; Anhedonia; Animals; Chronic Disease; Corpus Striatum; Eating; In Situ Hybridization; | 2011 |
Use of zinc as a treatment for traumatic brain injury in the rat: effects on cognitive and behavioral outcomes.
Topics: Anhedonia; Animals; Anxiety; Behavior, Animal; Brain Injuries; Cognition Disorders; Combined Modalit | 2012 |
A rat model of pre-puberty (juvenile) stress-induced predisposition to stress-related disorders: sex similarities and sex differences in effects and symptoms.
Topics: Age Factors; Anhedonia; Animals; Anxiety; Behavior, Animal; Depression; Disease Models, Animal; Fema | 2014 |