saccharin has been researched along with Alcohol Drinking in 167 studies
Saccharin: Flavoring agent and non-nutritive sweetener.
saccharin : A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether nalfurafine alone or in combination with mu-opioid receptor (MOP-r) antagonist naltrexone changed excessive alcohol drinking in male and female C57BL/6J (B6) mice subjected to a chronic intermittent-access drinking paradigm (2-bottle choice, 24-hour access every other day) for 3 weeks." | 7.91 | Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice. ( Kreek, MJ; Zhou, Y, 2019) |
| "Clonidine is an α2-adrenergic receptor agonist which, at low doses, inhibits noradrenergic signaling by decreasing norepinephrine release from presynaptic noradrenergic neurons." | 5.40 | The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats. ( Alexander, L; Federoff, D; Froehlich, JC; Malone, J; Rasmussen, DD, 2014) |
| "These data suggest that an alcohol drinking history induces maladaptive behaviors, such as drinking in spite of negative consequences, a pattern not seen with saccharin." | 3.91 | Innate and Acquired Quinine-Resistant Alcohol, but not Saccharin, Drinking in Crossed High-Alcohol-Preferring Mice. ( Carron, CR; Grahame, NJ; Houck, CA; Millie, LA, 2019) |
| " Silencing of miR-411 by infusing antagomiR-411 into the prefrontal cortex of female C57BL/6J mice reduced alcohol consumption and preference, without altering total fluid consumption, saccharin consumption, or anxiety-related behaviors." | 3.91 | Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice. ( Blednov, YA; Harris, RA; Mayfield, RD; Most, D; Salem, NA; Tiwari, GR, 2019) |
| "We investigated whether nalfurafine alone or in combination with mu-opioid receptor (MOP-r) antagonist naltrexone changed excessive alcohol drinking in male and female C57BL/6J (B6) mice subjected to a chronic intermittent-access drinking paradigm (2-bottle choice, 24-hour access every other day) for 3 weeks." | 3.91 | Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice. ( Kreek, MJ; Zhou, Y, 2019) |
| " Additional experiments assessed the influence of (i) adulteration with quinine of the alcohol solution (Experiment 2) and (ii) concurrent presentation of a saccharin solution (Experiment 3) on alcohol drinking under the CA10% and IA20% conditions." | 3.76 | Increase in alcohol intake, reduced flexibility of alcohol drinking, and evidence of signs of alcohol intoxication in Sardinian alcohol-preferring rats exposed to intermittent access to 20% alcohol. ( Carai, MA; Colombo, G; Fantini, N; Gessa, GL; Lobina, C; Loi, B; Maccioni, P, 2010) |
| "Previous studies showed that the 5-HT2 receptor antagonist, amperozide, is somewhat more potent than the opiate antagonist, naltrexone, in reducing alcohol drinking in high alcohol-preferring (P) rats." | 3.70 | Naltrexone and amperozide modify chocolate and saccharin drinking in high alcohol-preferring P rats. ( Biggs, TA; Myers, RD, 1998) |
| " There was a significant dose-response relationship with lifelong coffee drinking and alcohol consumption; however the risk estimates were only significantly elevated for the heaviest drinkers." | 2.67 | Relative importance of risk factors in bladder carcinogenesis: some new results about Mediterranean habits. ( Bontoux, J; Daurès, JP; Festy, B; Grémy, F; Momas, I, 1994) |
| "Binge alcohol drinking is a health burden in the United States, which has an alarming economic impact." | 1.51 | The α3β4 nicotinic acetylcholine receptor antagonist 18-Methoxycoronaridine decreases binge-like ethanol consumption in adult C57BL/6J mice. ( Kamens, HM; Miller, CN; Ruggery, C, 2019) |
| " Chronic administration of apremilast (20 mg/kg) produced a stable reduction in EtOH consumption in both drinking tests with no effect on total fluid intake." | 1.48 | Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Consumption and Preference. ( Blednov, YA; Da Costa, AJ; Harris, RA; Messing, RO; Ponomareva, O; Tarbox, T, 2018) |
| " However, after chronic intake is achieved (maintenance phase), EtOH intake becomes independent of acetaldehyde generation or its levels." | 1.43 | Beyond the "First Hit": Marked Inhibition by N-Acetyl Cysteine of Chronic Ethanol Intake But Not of Early Ethanol Intake. Parallel Effects on Ethanol-Induced Saccharin Motivation. ( Berríos-Cárcamo, P; Herrera-Marschitz, M; Israel, Y; Quintanilla, ME; Rivera-Meza, M; Salinas-Luypaert, C, 2016) |
| "Voluntary drinking of 20 % ethanol in an every-other-day (EOD) availability pattern and the dose-response relationship of ethanol conditioned taste aversion (CTA) were assessed in male and female adolescent and adult rats." | 1.40 | Effect of sex on ethanol consumption and conditioned taste aversion in adolescent and adult rats. ( Francis, R; Keistler, C; Kuhn, CM; MacDonald, A; O'Neill, L; Schramm-Sapyta, NL, 2014) |
| "Clonidine is an α2-adrenergic receptor agonist which, at low doses, inhibits noradrenergic signaling by decreasing norepinephrine release from presynaptic noradrenergic neurons." | 1.40 | The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats. ( Alexander, L; Federoff, D; Froehlich, JC; Malone, J; Rasmussen, DD, 2014) |
| "Comorbid chronic stress and alcohol dependence may lead to a complicated and potentially severe treatment profile." | 1.39 | Increased anxiety, voluntary alcohol consumption and ethanol-induced place preference in mice following chronic psychosocial stress. ( Bahi, A, 2013) |
| "Repeated dosing (0." | 1.39 | Varenicline and cytisine: two nicotinic acetylcholine receptor ligands reduce ethanol intake in University of Chile bibulous rats. ( Busto, UE; Cassels, BK; Gysling, K; Quintanilla, ME; Sotomayor-Zárate, R; Tampier, L, 2013) |
| "Treatment with SNAP 37889 (30 mg/kg, i." | 1.37 | The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats. ( Ash, BL; Djouma, E; Lawrence, AJ; Williams, SJ; Zanatta, SD, 2011) |
| "25 microg) of ICS significantly increased responding on the ethanol lever; after the 7-day dosing regimen, responding on the ethanol lever returned to control levels." | 1.36 | Serotonin-3 receptors in the posterior ventral tegmental area regulate ethanol self-administration of alcohol-preferring (P) rats. ( Bell, RL; McBride, WJ; Murphy, JM; Oster, SM; Pommer, TJ; Rodd, ZA; Toalston, JE, 2010) |
| "When saccharin was replaced by sodium chloride, no differences in CTA to alcohol between knockout and wild-type mice were seen." | 1.35 | Perception of sweet taste is important for voluntary alcohol consumption in mice. ( Blednov, YA; Damak, S; Levine, M; Margolskee, RF; Martinez, M; Walker, D, 2008) |
| "Epidemiological studies suggest that alcohol abuse during the adolescent developmental period may result in long-term changes such as an increased susceptibility to alcohol-related problems in adulthood." | 1.34 | The effects of continuous and intermittent ethanol exposure in adolesence on the aversive properties of ethanol during adulthood. ( Diaz-Granados, JL; Graham, DL, 2007) |
| "Topiramate has recently been found to be more effective than placebo as an adjunct treatment for alcohol dependence, but it has not yet been investigated in animal models of ethanol consumption." | 1.33 | Effects of topiramate on ethanol and saccharin consumption and preferences in C57BL/6J mice. ( Cunningham, CL; Gabriel, KI, 2005) |
| "Cyanamide pretreatments significantly potentiated ethanol- but not acetaldehyde-induced CTA." | 1.32 | Role of acetaldehyde in ethanol-induced conditioned taste aversion in rats. ( De Witte, P; Escarabajal, MD; Quertemont, E, 2003) |
| " Stable isoforms of deltafosB called chronic FRAs accumulate in the brain after chronic administration of various drugs of abuse." | 1.32 | Dissociation of ethanol and saccharin preference in fosB knockout mice. ( Bienkowski, P; Kaczmarek, L; Kolomanska, P; Korkosz, A; Kostowski, W; Kowalska, K; Mierzejewski, P; Radwanska, K; Rogowski, A; Scinska, A, 2004) |
| " In this study, we subjected these rats to several long-term administration protocols suggested to favour the development of alcohol dependence, including multiple alcohol concentrations or sweetened alcohol solutions (ethanol 10% or 20%+saccharin), and deprivation periods." | 1.32 | The High-Ethanol Preferring rat as a model to study the shift between alcohol abuse and dependence. ( Jones, BC; Mormède, P; Terenina-Rigaldie, E, 2004) |
| "The saccharin solution was offered, in free choice with water, at a fixed concentration of 1 g/liter for 6 consecutive days in Experiment 1A or at ascending concentrations (0." | 1.31 | Dissociation of ethanol and saccharin preference in sP and sNP rats. ( Agabio, R; Bourov, I; Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Pani, M; Reali, R, 2000) |
| "Treatment with fluoxetine resulted in a dose-dependent decrease in saccharin intake to, but not below, the normal level of their DFI." | 1.30 | Fluoxetine reduces saccharin-induced elevation of fluid intake in alcohol-preferring Fawn-Hooded rats. ( Kampov-Polevoy, AB; Rezvani, AH, 1997) |
| "Saccharin consumption was not significantly affected by any of the treatments." | 1.29 | Effects of stress and ebiratide (Hoe-427) on free-choice ethanol consumption: comparison of Lewis and Sprague-Dawley rats. ( Maickel, RP; Sprague, JE, 1994) |
| "The study of alcohol abuse traditionally has placed great emphasis on the development of tolerance and dependence as key factors." | 1.29 | Effects of chronic ethanol exposure on oral self-administration of ethanol or saccharin by Wistar rats. ( Heinrichs, SC; Hyytiä, P; Koob, GF; Schulteis, G, 1996) |
| "Saccharin intake was redetermined after each phase of the experiment." | 1.29 | The relationships among saccharin consumption, oral ethanol, and i.v. cocaine self-administration. ( Carroll, ME; Gahtan, E; Labounty, LP; Wyvell, C, 1996) |
| "Saccharin intake was either not altered by RO19-4603 or showed increases during the initial 15 min intervals and the total 4 h sessions on days 1 and 2." | 1.29 | Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426 and CGS 8216, on ethanol intake in alcohol-preferring (P) rats. ( Cason, CR; Cox, R; Duemler, SE; Greene, TL; Hite, ML; June, HL; Li, TK; Lumeng, L; Mellon-Burke, J; Murphy, JM; Torres, L; Williams, JA, 1996) |
| "The relationship between bladder cancer and alcohol consumption was investigated in a case-control study conducted in 506 patients (453 males and 53 females) with diagnoses of papillary urothelial carcinoma during 1978-1982 at "La Paz" hospital (Madrid), and an equal number of controls matched for age, sex and date of admission to the hospital." | 1.27 | Bladder cancer and the consumption of alcoholic beverages in Spain. ( Bravo, MP; Conde, M; Del Rey Calero, J, 1987) |
| "A case-control study of bladder cancer in two northern counties of New Jersey was conducted to investigate a tumour that has been considered to be strongly associated with industrial and environmental exposures." | 1.26 | Life time occupation, smoking, caffeine, saccharine, hair dyes and bladder carcinogenesis. ( Ambrose, RB; Fernicola, AR; Louria, DB; Najem, GR; Prusakowski, JM; Seebode, JJ; Thind, IS, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (19.76) | 18.7374 |
| 1990's | 29 (17.37) | 18.2507 |
| 2000's | 52 (31.14) | 29.6817 |
| 2010's | 47 (28.14) | 24.3611 |
| 2020's | 6 (3.59) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, R | 1 |
| Parikh, M | 1 |
| Mishra, V | 1 |
| Soni, A | 1 |
| Rubi, S | 1 |
| Sahota, P | 1 |
| Thakkar, M | 1 |
| Leyrer-Jackson, JM | 1 |
| Hood, LE | 1 |
| Olive, MF | 1 |
| Bauer, MR | 1 |
| Hernández, M | 1 |
| Kasten, CR | 1 |
| Boehm, SL | 1 |
| Chandler, CM | 1 |
| Shaykin, JD | 1 |
| Peng, H | 1 |
| Pauly, JR | 1 |
| Nixon, K | 1 |
| Bardo, MT | 1 |
| Houck, CA | 1 |
| Carron, CR | 1 |
| Millie, LA | 1 |
| Grahame, NJ | 1 |
| Gamble, DN | 1 |
| Josefson, CC | 1 |
| Hennessey, MK | 1 |
| Davis, AM | 1 |
| Waters, RC | 1 |
| Jones, BN | 1 |
| Belton, DM | 1 |
| Hall, NI | 1 |
| Costen, TJ | 1 |
| Kirstein, CL | 1 |
| Maldonado-Devincci, AM | 1 |
| Shah, K | 1 |
| Shaw, C | 1 |
| Sirohi, S | 1 |
| Bezerra-Karounis, MA | 1 |
| Krahe, TE | 1 |
| Maisonnette, S | 1 |
| Landeira-Fernandez, J | 1 |
| Kamens, HM | 3 |
| Peck, C | 2 |
| Garrity, C | 1 |
| Gechlik, A | 1 |
| Jenkins, BC | 1 |
| Rajan, A | 1 |
| Silva, C | 1 |
| Miller, CN | 2 |
| Puaud, M | 1 |
| Ossowska, Z | 1 |
| Barnard, J | 1 |
| Milton, AL | 1 |
| Blednov, YA | 6 |
| Da Costa, AJ | 1 |
| Tarbox, T | 1 |
| Ponomareva, O | 1 |
| Messing, RO | 2 |
| Harris, RA | 5 |
| Most, D | 1 |
| Salem, NA | 1 |
| Tiwari, GR | 1 |
| Mayfield, RD | 1 |
| Ruggery, C | 1 |
| Bahi, A | 4 |
| Dreyer, JL | 1 |
| Gore-Langton, JK | 1 |
| Spear, LP | 2 |
| Zhou, Y | 1 |
| Kreek, MJ | 2 |
| Peana, AT | 2 |
| Muggironi, G | 2 |
| Fois, G | 1 |
| Diana, M | 1 |
| Crabbe, JC | 4 |
| Spence, SE | 2 |
| Huang, LC | 1 |
| Cameron, AJ | 1 |
| Schlumbohm, JP | 1 |
| Barkley-Levenson, AM | 1 |
| Metten, P | 2 |
| Schramm-Sapyta, NL | 1 |
| Francis, R | 1 |
| MacDonald, A | 1 |
| Keistler, C | 1 |
| O'Neill, L | 1 |
| Kuhn, CM | 1 |
| Dess, NK | 1 |
| Madkins, CD | 1 |
| Geary, BA | 1 |
| Chapman, CD | 1 |
| Darcq, E | 2 |
| Hamida, SB | 1 |
| Wu, S | 1 |
| Phamluong, K | 1 |
| Kharazia, V | 1 |
| Xu, J | 1 |
| Lombroso, P | 1 |
| Ron, D | 2 |
| Rasmussen, DD | 1 |
| Alexander, L | 1 |
| Malone, J | 1 |
| Federoff, D | 1 |
| Froehlich, JC | 3 |
| Al Ameri, M | 1 |
| Al Mansouri, S | 1 |
| Al Maamari, A | 1 |
| Spina, L | 1 |
| Rosas, M | 1 |
| Kasture, SB | 1 |
| Cotti, E | 1 |
| Acquas, E | 1 |
| Dudek, M | 1 |
| Abo-Ramadan, U | 1 |
| Hermann, D | 1 |
| Brown, M | 1 |
| Canals, S | 1 |
| Sommer, WH | 1 |
| Hyytiä, P | 3 |
| Ford, MM | 3 |
| Nickel, JD | 2 |
| Kaufman, MN | 1 |
| Finn, DA | 3 |
| Seif, T | 1 |
| Simms, JA | 1 |
| Lei, K | 1 |
| Wegner, S | 1 |
| Bonci, A | 1 |
| Hopf, FW | 1 |
| Walker, AW | 1 |
| Smith, CM | 1 |
| Chua, BE | 1 |
| Krstew, EV | 1 |
| Zhang, C | 1 |
| Gundlach, AL | 1 |
| Lawrence, AJ | 2 |
| Miranda-Morales, RS | 1 |
| Pautassi, RM | 1 |
| Legastelois, R | 1 |
| Wegner, SA | 1 |
| Lombroso, PJ | 1 |
| Stafford, AM | 1 |
| Anderson, SM | 1 |
| Shelton, KL | 1 |
| Brunzell, DH | 1 |
| McMurray, KM | 1 |
| Sidhu, PS | 1 |
| Cook, JM | 1 |
| Arnold, LA | 1 |
| Palmer, AA | 2 |
| Dyr, W | 3 |
| Wyszogrodzka, E | 1 |
| Paterak, J | 1 |
| Siwińska-Ziółkowska, A | 1 |
| Małkowska, A | 1 |
| Polak, P | 1 |
| Quintanilla, ME | 4 |
| Rivera-Meza, M | 1 |
| Berríos-Cárcamo, P | 1 |
| Salinas-Luypaert, C | 1 |
| Herrera-Marschitz, M | 1 |
| Israel, Y | 1 |
| Augier, E | 1 |
| Dulman, RS | 1 |
| Rauffenbart, C | 1 |
| Augier, G | 1 |
| Cross, AJ | 1 |
| Heilig, M | 1 |
| Lyons, AM | 1 |
| Lowery, EG | 1 |
| Sparta, DR | 1 |
| Thiele, TE | 2 |
| Sabino, V | 1 |
| Cottone, P | 1 |
| Zhao, Y | 1 |
| Iyer, MR | 1 |
| Steardo, L | 2 |
| Rice, KC | 1 |
| Conti, B | 1 |
| Koob, GF | 4 |
| Zorrilla, EP | 1 |
| Tampier, L | 3 |
| Fretwell, AM | 1 |
| Mark, GP | 1 |
| Strong, MN | 1 |
| Yoneyama, N | 2 |
| Navarro, M | 2 |
| Cubero, I | 1 |
| Ko, L | 1 |
| Vendruscolo, LF | 1 |
| Gueye, AB | 1 |
| Vendruscolo, JC | 1 |
| Clemens, KJ | 1 |
| Mormède, P | 4 |
| Darnaudéry, M | 1 |
| Cador, M | 1 |
| Rodd, ZA | 2 |
| Bell, RL | 3 |
| Oster, SM | 2 |
| Toalston, JE | 2 |
| Pommer, TJ | 2 |
| McBride, WJ | 6 |
| Murphy, JM | 7 |
| Gulick, D | 1 |
| Green, AI | 1 |
| Ash, BL | 1 |
| Zanatta, SD | 1 |
| Williams, SJ | 1 |
| Djouma, E | 1 |
| Oberlin, B | 1 |
| Best, C | 1 |
| Matson, L | 1 |
| Henderson, A | 1 |
| Grahame, N | 1 |
| Loi, B | 1 |
| Lobina, C | 5 |
| Maccioni, P | 3 |
| Fantini, N | 1 |
| Carai, MA | 5 |
| Gessa, GL | 5 |
| Colombo, G | 5 |
| Brown, LL | 1 |
| Ponomarev, I | 1 |
| Geil, C | 1 |
| Bergeson, S | 1 |
| Fizia, K | 1 |
| Dietz, M | 1 |
| Gasparini, F | 1 |
| Flor, PJ | 1 |
| Pastor, R | 1 |
| Reed, C | 1 |
| Burkhart-Kasch, S | 3 |
| Li, N | 1 |
| Sharpe, AL | 2 |
| Coste, SC | 2 |
| Stenzel-Poore, MP | 2 |
| Phillips, TJ | 3 |
| Anacker, AM | 1 |
| Loftis, JM | 1 |
| Ryabinin, AE | 1 |
| Hulin, MW | 1 |
| Amato, RJ | 1 |
| Winsauer, PJ | 1 |
| Benavidez, JM | 1 |
| Homanics, GE | 1 |
| Pohorecky, LA | 2 |
| Sweeny, A | 1 |
| Salinas, AG | 1 |
| Nguyen, CT | 1 |
| Ahmadi-Tehrani, D | 1 |
| Morrisett, RA | 1 |
| Sotomayor-Zárate, R | 1 |
| Gysling, K | 1 |
| Busto, UE | 1 |
| Cassels, BK | 1 |
| Cichelli, MJ | 1 |
| Lewis, MJ | 1 |
| Rodd-Henricks, ZA | 1 |
| Webster, AA | 1 |
| Lumeng, L | 7 |
| Li, TK | 7 |
| Ackroff, K | 1 |
| Sclafani, A | 1 |
| Reid, ML | 1 |
| Hubbell, CL | 1 |
| Reid, LD | 1 |
| Escarabajal, MD | 1 |
| De Witte, P | 3 |
| Quertemont, E | 1 |
| Ingman, K | 1 |
| Honkanen, A | 1 |
| Huttunen, MO | 1 |
| Korpi, ER | 1 |
| Werme, M | 1 |
| Hermanson, E | 1 |
| Carmine, A | 1 |
| Buervenich, S | 1 |
| Zetterström, RH | 1 |
| Thorén, P | 1 |
| Ogren, SO | 1 |
| Olson, L | 1 |
| Perlmann, T | 1 |
| Brené, S | 1 |
| Salimov, RM | 1 |
| Maisky, AI | 1 |
| Hori, H | 1 |
| Fujii, W | 1 |
| Hatanaka, Y | 1 |
| Suwa, Y | 1 |
| Terenina-Rigaldie, E | 2 |
| Moisan, MP | 1 |
| Colas, A | 1 |
| Beaugé, F | 1 |
| Shah, KV | 1 |
| Jones, BC | 2 |
| McQuade, JA | 1 |
| Xu, M | 1 |
| Woods, SC | 1 |
| Seeley, RJ | 1 |
| Benoit, SC | 1 |
| McKinnon, CS | 2 |
| Korkosz, A | 1 |
| Kolomanska, P | 1 |
| Kowalska, K | 1 |
| Rogowski, A | 1 |
| Radwanska, K | 1 |
| Kaczmarek, L | 1 |
| Mierzejewski, P | 1 |
| Scinska, A | 1 |
| Kostowski, W | 2 |
| Bienkowski, P | 1 |
| Gabriel, KI | 1 |
| Cunningham, CL | 2 |
| Kovacs, KM | 1 |
| Szakall, I | 1 |
| O'Brien, D | 1 |
| Wang, R | 1 |
| Vinod, KY | 1 |
| Saito, M | 1 |
| Simonin, F | 1 |
| Kieffer, BL | 1 |
| Vadasz, C | 1 |
| Mascia, MF | 2 |
| Orrù, A | 2 |
| Broadbent, J | 1 |
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| Wenger, CD | 1 |
| McMullin, C | 1 |
| Brunell, SC | 1 |
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| Weiss, JM | 1 |
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| Liljequist, S | 2 |
| Schiöth, HB | 1 |
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| Flint, WW | 1 |
| Higley, JD | 1 |
| Riley, AL | 1 |
| Walker, D | 2 |
| Martinez, M | 2 |
| Levine, M | 1 |
| Damak, S | 1 |
| Margolskee, RF | 1 |
| Truxell, EM | 1 |
| Molina, JC | 1 |
| Spear, NE | 2 |
| Cippitelli, A | 1 |
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| Gorriti, MA | 1 |
| Massi, M | 2 |
| Piomelli, D | 1 |
| Ciccocioppo, R | 2 |
| Rodríguez de Fonseca, F | 1 |
| Diaz-Granados, JL | 1 |
| Graham, DL | 1 |
| Kozlov, AP | 1 |
| Varlinskaya, EI | 1 |
| Murillo, A | 1 |
| Kuc, KA | 1 |
| Michiels, M | 1 |
| Graham, S | 1 |
| Najem, GR | 1 |
| Louria, DB | 1 |
| Seebode, JJ | 1 |
| Thind, IS | 1 |
| Prusakowski, JM | 1 |
| Ambrose, RB | 1 |
| Fernicola, AR | 1 |
| Cartwright, RA | 1 |
| Adib, R | 1 |
| Glashan, R | 1 |
| Gray, BK | 1 |
| Krishnan-Sarin, S | 1 |
| Jing, SL | 1 |
| Kurtz, DL | 1 |
| Zweifel, M | 1 |
| Portoghese, PS | 1 |
| Kampov-Polevoy, AB | 4 |
| Overstreet, DH | 6 |
| Rezvani, AH | 8 |
| Janowsky, DS | 4 |
| Panocka, I | 1 |
| Pompei, P | 1 |
| Polidori, C | 1 |
| de Caro, G | 1 |
| Hyyatiä, P | 1 |
| Sinclair, JD | 2 |
| Belknap, JK | 1 |
| Young, ER | 1 |
| Sprague, JE | 2 |
| Maickel, RP | 2 |
| Momas, I | 1 |
| Daurès, JP | 1 |
| Festy, B | 1 |
| Bontoux, J | 1 |
| Grémy, F | 1 |
| Zabik, JE | 1 |
| Binkerd, K | 1 |
| Murrelle, L | 1 |
| Halikas, JA | 1 |
| Schulteis, G | 1 |
| Heinrichs, SC | 1 |
| Gahtan, E | 1 |
| Labounty, LP | 1 |
| Wyvell, C | 1 |
| Carroll, ME | 1 |
| Pucilowski, O | 2 |
| June, HL | 1 |
| Greene, TL | 1 |
| Hite, ML | 1 |
| Williams, JA | 1 |
| Cason, CR | 1 |
| Mellon-Burke, J | 1 |
| Cox, R | 2 |
| Duemler, SE | 1 |
| Torres, L | 1 |
| Plummer, JL | 1 |
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| Biggs, TA | 1 |
| Myers, RD | 1 |
| Goodwin, FL | 4 |
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| Roberts, AJ | 1 |
| Heyser, CJ | 1 |
| Nowak, KL | 2 |
| Agabio, R | 1 |
| Pani, M | 1 |
| Reali, R | 1 |
| Bourov, I | 1 |
| Bergeron, N | 1 |
| Blakley, GG | 1 |
| Benjamin, D | 1 |
| Bowers, BJ | 1 |
| Wehner, JM | 1 |
| Campisi, M | 1 |
| Babinska, I | 1 |
| Zhang, M | 1 |
| Kelley, AE | 1 |
| Cailhol, S | 1 |
| Foroud, T | 1 |
| Bice, P | 1 |
| Castelluccio, P | 1 |
| Bo, R | 1 |
| Ritchotte, A | 1 |
| Stewart, R | 1 |
| Carr, L | 1 |
| Brunetti, G | 1 |
| Melis, S | 1 |
| Serra, S | 1 |
| Vacca, G | 1 |
| Fernández-Teruel, A | 1 |
| Driscoll, P | 1 |
| Gil, L | 1 |
| Aguilar, R | 1 |
| Tobeña, A | 1 |
| Escorihuela, RM | 1 |
| Gilbert, RM | 3 |
| Parker, LF | 1 |
| Radow, BL | 1 |
| Stein, JM | 1 |
| Wayner, MJ | 3 |
| Tilson, HA | 1 |
| Hannon, R | 2 |
| Donlon-Bantz, K | 2 |
| Kulkosky, PJ | 1 |
| Cornell, NW | 1 |
| Mills, KC | 2 |
| Bean, JW | 2 |
| Hutcheson, JS | 2 |
| Ewing, JA | 1 |
| Marfaing-Jallat, P | 1 |
| Le Magnen, J | 3 |
| Whitney, G | 2 |
| Horowitz, GP | 2 |
| Falk, JL | 1 |
| Samson, HH | 1 |
| Riley, EP | 1 |
| Freed, EX | 2 |
| Pinel, JP | 1 |
| Huang, E | 1 |
| Krishnan, S | 1 |
| Linseman, MA | 1 |
| Harts, J | 1 |
| Bravo, MP | 1 |
| Del Rey Calero, J | 1 |
| Conde, M | 1 |
| Opitz, K | 1 |
| Lester, D | 2 |
| Fraley, S | 2 |
| Greenberg, I | 1 |
| Tartaglione, R | 1 |
| Nolley, D | 1 |
| Cott, A | 1 |
| Berman, RF | 1 |
| Cannon, DS | 1 |
| Nachman, M | 2 |
| Larue, C | 1 |
| Cicero, TJ | 1 |
| Snider, SR | 1 |
| Perez, VJ | 1 |
| Swanson, LW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of N-acetylcysteine for Alcohol Use Disorder[NCT04964843] | Phase 2 | 0 participants (Actual) | Interventional | 2023-04-30 | Withdrawn (stopped due to Null results were posted from a neurometabolite study and a recent trial for AUD. Study may resume if more positive data emerge.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for saccharin and Alcohol Drinking
| Article | Year |
|---|---|
Dietary factors in the prevention of cancer.
Topics: Alcohol Drinking; Ascorbic Acid; Coffee; Diet; Dietary Fats; Humans; Neoplasms; Risk; Saccharin; Veg | 1984 |
Schedule-induced physical dependence on ethanol.
Topics: Alcohol Drinking; Animals; Disease Models, Animal; Drinking Behavior; Drug Administration Schedule; | 1975 |
1 trial available for saccharin and Alcohol Drinking
| Article | Year |
|---|---|
Relative importance of risk factors in bladder carcinogenesis: some new results about Mediterranean habits.
Topics: Age Factors; Aged; Alcohol Drinking; Beverages; Case-Control Studies; Coffee; Feeding Behavior; Fran | 1994 |
164 other studies available for saccharin and Alcohol Drinking
| Article | Year |
|---|---|
Antisense-induced downregulation of major circadian genes modulates the expression of histone deacetylase-2 (HDAC-2) and CREB-binding protein (CBP) in the medial shell region of nucleus accumbens of mice exposed to chronic excessive alcohol consumption.
Topics: Alcohol Drinking; Animals; CREB-Binding Protein; Down-Regulation; Ethanol; Male; Mice; Mice, Inbred | 2022 |
Sex differences and the lack of effects of chemogenetic manipulation of pro-opiomelanocortin (POMC) neurons on alcohol consumption in male and female mice.
Topics: Alcohol Drinking; Animals; beta-Endorphin; Ethanol; Female; Male; Mice; Neurons; Pro-Opiomelanocorti | 2022 |
Systemic administration of racemic baclofen reduces both acquisition and maintenance of alcohol consumption in male and female mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Baclofen; Ethanol; Female; GABA-B Receptor Agonists; Male; Mi | 2022 |
Effects of voluntary adolescent intermittent alcohol exposure and social isolation on adult alcohol intake in male rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Ethanol; Male; Rats; Saccharin; Social Isolation; Water | 2022 |
Innate and Acquired Quinine-Resistant Alcohol, but not Saccharin, Drinking in Crossed High-Alcohol-Preferring Mice.
Topics: Alcohol Drinking; Animals; Disease Models, Animal; Female; Male; Mice; Quinine; Saccharin | 2019 |
Social Interaction With an Alcohol-Intoxicated or Cocaine-Injected Peer Selectively Alters Social Behaviors and Drinking in Adolescent Male and Female Rats.
Topics: Age Factors; Alcohol Drinking; Alcoholic Intoxication; Animals; Behavior, Animal; Cocaine; Female; I | 2019 |
Reduced alcohol drinking following patterned feeding: Role of palatability and acute contingent availability.
Topics: Alcohol Drinking; Animals; Diet, High-Fat; Ethanol; Male; Rats; Rats, Long-Evans; Saccharin | 2020 |
Alcohol intake in Carioca High- and Low-conditioned Freezing rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Anxiety Disorders; Conditioning, Psychological; Disease Model | 2020 |
α6β2 nicotinic acetylcholine receptors influence locomotor activity and ethanol consumption.
Topics: Alcohol Drinking; Animals; Binge Drinking; Ethanol; Female; Locomotion; Male; Mice; Mice, Inbred C57 | 2017 |
Varenicline modulates ethanol and saccharin consumption in adolescent male and female C57BL/6J mice.
Topics: Age Factors; Alcohol Drinking; Analysis of Variance; Animals; Animals, Newborn; Central Nervous Syst | 2018 |
Saccharin fading is not required for the acquisition of alcohol self-administration, and can alter the dynamics of cue-alcohol memory reconsolidation.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Cues; Dizocilpine Maleate; Ethanol; Male; Memory; | 2018 |
Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Consumption and Preference.
Topics: Alcohol Drinking; Animals; Brain; Choice Behavior; Ethanol; Female; Food Preferences; Liver; Male; M | 2018 |
Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice.
Topics: Alcohol Drinking; Amidohydrolases; Animals; Antagomirs; Anxiety; Argonaute Proteins; Behavior, Anima | 2019 |
The α3β4 nicotinic acetylcholine receptor antagonist 18-Methoxycoronaridine decreases binge-like ethanol consumption in adult C57BL/6J mice.
Topics: Alcohol Drinking; Animals; Binge Drinking; Ethanol; Female; Hypnotics and Sedatives; Ibogaine; Locom | 2019 |
No effect of sex on ethanol intake and preference after dopamine transporter (DAT) knockdown in adult mice.
Topics: Alcohol Drinking; Animals; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ethanol; Female; H | 2019 |
Prenatal ethanol exposure attenuates sensitivity to the aversive effects of ethanol in adolescence and increases adult preference for a 5% ethanol solution in males, but not females.
Topics: Age Factors; Alcohol Drinking; Animals; Avoidance Learning; Central Nervous System Depressants; Cond | 2019 |
Combination of Clinically Utilized Kappa-Opioid Receptor Agonist Nalfurafine With Low-Dose Naltrexone Reduces Excessive Alcohol Drinking in Male and Female Mice.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Drug Evaluation, Preclinic | 2019 |
Alpha-lipoic acid reduces ethanol self-administration in rats.
Topics: Alcohol Drinking; Alcohol-Related Disorders; Animals; Drug Evaluation, Preclinical; Ethanol; Hydroge | 2013 |
Ethanol drinking in withdrawal seizure-prone and -resistant selected mouse lines.
Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Animals; Darkness; Female; Male; Mice; Mice, Inbred S | 2013 |
Effect of sex on ethanol consumption and conditioned taste aversion in adolescent and adult rats.
Topics: Aging; Alcohol Drinking; Animals; Animals, Outbred Strains; Avoidance Learning; Central Nervous Syst | 2014 |
"Jello® shots" and cocktails as ethanol vehicles: parametric studies with high- and low-saccharin-consuming rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Eating; Ethanol; Food Deprivation; Food Pre | 2013 |
Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption.
Topics: Alcohol Drinking; Animals; Antibodies, Blocking; Blotting, Western; Choice Behavior; Down-Regulation | 2014 |
The α2-adrenergic receptor agonist, clonidine, reduces alcohol drinking in alcohol-preferring (P) rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Alcohol Drinking; Animals; Choice Behavior; Clonidine; Drinkin | 2014 |
The histone deacetylase (HDAC) inhibitor valproic acid reduces ethanol consumption and ethanol-conditioned place preference in rats.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Choice Behavior; Conditioning, Psycho | 2014 |
Effects of Withania somnifera on oral ethanol self-administration in rats.
Topics: Administration, Oral; Alcohol Drinking; Animals; Baclofen; Conditioning, Operant; Dose-Response Rela | 2014 |
Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging.
Topics: Alcohol Drinking; Animals; Brain; Brain Mapping; Central Nervous System Depressants; Chlorides; Cont | 2015 |
Null mutation of 5α-reductase type I gene alters ethanol consumption patterns in a sex-dependent manner.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Drinking; Alleles; Animals; Biopsy; Ethanol; Female; | 2015 |
D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats.
Topics: Alcohol Drinking; Animals; Compulsive Behavior; Cycloserine; Ethanol; Excitatory Amino Acid Antagoni | 2015 |
Relaxin-3 receptor (RXFP3) signalling mediates stress-related alcohol preference in mice.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Ethanol; Feeding Behavior; | 2015 |
Pharmacological characterization of the nociceptin/orphanin FQ receptor on ethanol-mediated motivational effects in infant and adolescent rats.
Topics: Aging; Alcohol Drinking; Animals; Anxiety; Choice Behavior; Conditioning, Psychological; Ethanol; Fe | 2016 |
Striatal-enriched protein tyrosine phosphatase controls responses to aversive stimuli: implication for ethanol drinking.
Topics: Alcohol Drinking; Animals; Aversive Therapy; Conditioning, Psychological; Gene Deletion; Lithium Chl | 2015 |
Oral operant ethanol self-administration in the absence of explicit cues, food restriction, water restriction and ethanol fading in C57BL/6J mice.
Topics: Administration, Oral; Alcohol Drinking; Animals; Conditioning, Operant; Cues; Ethanol; Food Deprivat | 2015 |
Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Ethanol; Female; Ge | 2017 |
Ethanol-induced conditioned taste aversion in Warsaw Alcohol High-Preferring (WHP) and Warsaw Alcohol Low-Preferring (WLP) rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Avoidance Learning; Choice Behavior; Conditioning, Classical; | 2016 |
Beyond the "First Hit": Marked Inhibition by N-Acetyl Cysteine of Chronic Ethanol Intake But Not of Early Ethanol Intake. Parallel Effects on Ethanol-Induced Saccharin Motivation.
Topics: Acetylcysteine; Alcohol Drinking; Animals; Male; Motivation; Rats; Saccharin; Self Administration; T | 2016 |
The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relati | 2016 |
Effects of food availability and administration of orexigenic and anorectic agents on elevated ethanol drinking associated with drinking in the dark procedures.
Topics: Alcohol Drinking; Alcoholism; Animals; Appetite Depressants; Appetite Stimulants; Darkness; Disease | 2008 |
The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Conditioning, Operant; Disease Models, Animal; Ethanol | 2009 |
Effect of concurrent saccharin intake on ethanol consumption by high-alcohol-drinking (UChB) rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Choice Behavior; Drinking; Female; Motivation; Rats; Rats, In | 2009 |
The influence of mecamylamine on ethanol and sucrose self-administration.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Choice Behavior; Conditioning, Operant; Dose-Respon | 2009 |
Deletion of agouti-related protein blunts ethanol self-administration and binge-like drinking in mice.
Topics: Agouti-Related Protein; Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; C | 2009 |
Reduced alcohol drinking in adult rats exposed to sucrose during adolescence.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Choice Behavior; Ethanol; Male; Quinine; Rats; Rats | 2010 |
Serotonin-3 receptors in the posterior ventral tegmental area regulate ethanol self-administration of alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Ethanol; Female; Rats; Rats, Inbred Strains; Recep | 2010 |
Role of caloric homeostasis and reward in alcohol intake in Syrian golden hamsters.
Topics: Alcohol Drinking; Animals; Appetite Regulation; Calorimetry; Choice Behavior; Cricetinae; Dose-Respo | 2010 |
The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Anxiety; Behavior, Animal; Conditioning, Operant; Indoles; Male; Rats; Re | 2011 |
Derivation and characterization of replicate high- and low-alcohol preferring lines of mice and a high-drinking crossed HAP line.
Topics: Alcohol Drinking; Alleles; Animals; Choice Behavior; Crosses, Genetic; Disease Models, Animal; Ethan | 2011 |
Increase in alcohol intake, reduced flexibility of alcohol drinking, and evidence of signs of alcohol intoxication in Sardinian alcohol-preferring rats exposed to intermittent access to 20% alcohol.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Animals; Choice Behavior; Disease Models, Anim | 2010 |
Alcohol preference drinking in a mouse line selectively bred for high drinking in the dark.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Breeding; Choice Behavior; Darkness; Disease Models, An | 2011 |
Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Behavior, Animal; beta 2-Microglobulin; Cathepsin F | 2012 |
Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats.
Topics: Alcohol Drinking; Animals; Benzhydryl Compounds; Ethanol; Food Preferences; Male; Motor Activity; Py | 2012 |
Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice.
Topics: Alcohol Drinking; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female | 2011 |
Alcohol intake in prairie voles is influenced by the drinking level of a peer.
Topics: Alcohol Drinking; Animals; Arvicolinae; Behavior, Animal; Central Nervous System Depressants; Choice | 2011 |
GABA(A) receptor modulation during adolescence alters adult ethanol intake and preference in rats.
Topics: Aging; Alcohol Drinking; Animals; Data Interpretation, Statistical; Dehydroepiandrosterone; Dose-Res | 2012 |
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.
Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior | 2012 |
Amphetamine modifies ethanol intake of psychosocially stressed male rats.
Topics: Alcohol Drinking; Amphetamine; Animals; Behavior, Animal; Dopamine Agents; Drinking; Male; Rats; Rat | 2012 |
Reduced ethanol consumption and preference in cocaine- and amphetamine-regulated transcript (CART) knockout mice.
Topics: Alcohol Drinking; Analgesics, Non-Narcotic; Animals; Appetitive Behavior; Brain; Choice Behavior; Di | 2014 |
Increased anxiety, voluntary alcohol consumption and ethanol-induced place preference in mice following chronic psychosocial stress.
Topics: Alcohol Drinking; Alcoholism; Animals; Anxiety; Behavior, Addictive; Choice Behavior; Conditioning, | 2013 |
Varenicline and cytisine: two nicotinic acetylcholine receptor ligands reduce ethanol intake in University of Chile bibulous rats.
Topics: Alcohol Drinking; Alkaloids; Animals; Azocines; Benzazepines; Chile; Dose-Response Relationship, Dru | 2013 |
Naloxone nonselective suppression of drinking of ethanol, sucrose, saccharin, and water by rats.
Topics: Alcohol Drinking; Animals; Drinking; Ethanol; Male; Naloxone; Rats; Rats, Sprague-Dawley; Saccharin; | 2002 |
Heart rate and motor-activating effects of orally self-administered ethanol in alcohol-preferring (P) rats.
Topics: Administration, Oral; Alcohol Drinking; Animals; Ethanol; Heart Rate; Male; Motor Activity; Rats; Sa | 2002 |
Flavor quality and ethanol concentration affect ethanol-conditioned flavor preferences.
Topics: Alcohol Drinking; Animals; Body Weight; Central Nervous System Depressants; Conditioning, Operant; D | 2002 |
A pharmacological dose of estradiol can enhance appetites for alcoholic beverages.
Topics: Alcohol Drinking; Animals; Estradiol; Female; Rats; Rats, Sprague-Dawley; Saccharin; Stimulation, Ch | 2003 |
Role of acetaldehyde in ethanol-induced conditioned taste aversion in rats.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Cond | 2003 |
Risperidone reduces limited access alcohol drinking in alcohol-preferring rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Antipsychotic Agents; Disease Models, Animal; Dopamine D2 Rec | 2003 |
Decreased ethanol preference and wheel running in Nurr1-deficient mice.
Topics: Alcohol Drinking; Animals; Animals, Newborn; Behavior, Animal; Dinucleotide Repeats; DNA-Binding Pro | 2003 |
Differential effects of saccharin supplementation on alcohol and water consumption by Wistar rats from different sources.
Topics: Alcohol Drinking; Animals; Drinking; Ethanol; Male; Rats; Rats, Wistar; Saccharin | 2003 |
Effects of fusel oil on animal hangover models.
Topics: Alcohol Drinking; Alcoholic Beverages; Alcohols; Animals; Avoidance Learning; Conditioning, Classica | 2003 |
Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Chromosomes, Mammalian; Crosses, Genetic; Ethanol; Fema | 2003 |
Ethanol consumption in mice with a targeted disruption of the dopamine-3 receptor gene.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Ethanol; Genotype; Male; Mice; Mice, I | 2003 |
Corticotropin-releasing factor overexpression decreases ethanol drinking and increases sensitivity to the sedative effects of ethanol.
Topics: Aging; Alcohol Drinking; Animals; Avoidance Learning; Central Nervous System Depressants; Corticotro | 2004 |
Dissociation of ethanol and saccharin preference in fosB knockout mice.
Topics: Alcohol Drinking; Animals; Choice Behavior; Drinking Behavior; Ethanol; Female; Food Preferences; Ma | 2004 |
The High-Ethanol Preferring rat as a model to study the shift between alcohol abuse and dependence.
Topics: Alcohol Drinking; Alcoholism; Animals; Central Nervous System Depressants; Disease Models, Animal; E | 2004 |
Effects of topiramate on ethanol and saccharin consumption and preferences in C57BL/6J mice.
Topics: Alcohol Drinking; Animals; Choice Behavior; Dose-Response Relationship, Drug; Drinking; Ethanol; Fru | 2005 |
Decreased oral self-administration of alcohol in kappa-opioid receptor knock-out mice.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Drinking Behavior; Ethanol; Mice; Mic | 2005 |
Suppression of acquisition of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.
Topics: Alcohol Drinking; Animals; Choice Behavior; Male; Rats; Rats, Inbred Strains; Saccharin | 2005 |
Suppression of maintenance of alcohol-drinking behavior by the concurrent availability of saccharin in Sardinian alcohol-preferring (sP) rats.
Topics: Alcohol Drinking; Animals; Choice Behavior; Male; Rats; Rats, Inbred Strains; Saccharin | 2005 |
Genetic correlational analyses of ethanol reward and aversion phenotypes in short-term selected mouse lines bred for ethanol drinking or ethanol-induced conditioned taste aversion.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Association Learning; Avoidance Learning; Behavior, | 2005 |
Effect of stress on the voluntary intake of a sweetened ethanol solution in pair-housed adolescent and adult rats.
Topics: Age Factors; Alcohol Drinking; Animals; Body Temperature; Corticosterone; Freezing; Male; Maze Learn | 2005 |
Saccharin consumption and the effect of a long-term exposure to a sweetened alcoholic solution in high- (UChB) and low- (UChA) alcohol-drinking rats.
Topics: Alcohol Drinking; Alcoholic Beverages; Animals; Drinking; Ethanol; Female; Food Preferences; Genotyp | 2005 |
Intake of ethanol and reinforcing fluids in rats bred for susceptibility to stress.
Topics: Alcohol Drinking; Animals; Breeding; Disease Susceptibility; Drinking; Female; Male; Quinine; Rats; | 2006 |
Identification of neurotransmitter receptor genes involved in alcohol self-administration in the rat prefrontal cortex, hippocampus and amygdala.
Topics: Alcohol Drinking; Amygdala; Animals; Conditioning, Operant; DNA Primers; DNA, Complementary; Drinkin | 2007 |
The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking.
Topics: Alcohol Drinking; Alcohols; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relation | 2007 |
Assessment of the aversive and rewarding effects of alcohol in Fischer and Lewis rats.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Central Nervous S | 2006 |
Reduced alcohol consumption in mice lacking preprodynorphin.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Conditioning, Operant; Dynorphins; Et | 2006 |
Perception of sweet taste is important for voluntary alcohol consumption in mice.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Conditioning, Classical; Crosses, Genetic; Female; He | 2008 |
Ethanol intake in the juvenile, adolescent, and adult rat: effects of age and prior exposure to ethanol.
Topics: Aging; Alcohol Drinking; Animals; Central Nervous System Depressants; Ethanol; Female; Male; Rats; R | 2007 |
The anandamide transport inhibitor AM404 reduces ethanol self-administration.
Topics: Alcohol Drinking; Animals; Arachidonic Acids; Capsaicin; Central Nervous System Depressants; Conditi | 2007 |
The effects of continuous and intermittent ethanol exposure in adolesence on the aversive properties of ethanol during adulthood.
Topics: Administration, Inhalation; Age Factors; Alcohol Drinking; Alcoholism; Animals; Association Learning | 2007 |
Ethanol, saccharin, and quinine: early ontogeny of taste responsiveness and intake.
Topics: Age Factors; Alcohol Drinking; Animals; Animals, Newborn; Appetitive Behavior; Drinking Behavior; Fe | 2008 |
Voluntary ethanol consumption in 22 inbred mouse strains.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Data Interpretation | 2008 |
Effects of alcohol and saccharin deprivations on concurrent ethanol and saccharin operant self-administration by alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Opera | 2008 |
Compensatory effects of palatable and non-palatable substances on the ethanol consumption in a free-choice procedure in rats.
Topics: Alcohol Drinking; Animals; Male; Quinine; Rats; Rats, Inbred Strains; Saccharin; Taste | 1982 |
Naloxone reduces alcohol intake in a free-choice procedure even when both drinking bottles contain saccharin sodium or quinine substances.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Endorphins; Male; Naloxone; Quinine; Rats; Reward; Sac | 1984 |
Life time occupation, smoking, caffeine, saccharine, hair dyes and bladder carcinogenesis.
Topics: Alcohol Drinking; Caffeine; Female; Hair Dyes; Humans; Male; Neoplasms, Multiple Primary; New Jersey | 1982 |
The epidemiology of bladder cancer in West Yorkshire. A preliminary report on non-occupational aetiologies.
Topics: Alcohol Drinking; Coffee; England; Female; Humans; Male; Risk; Saccharin; Sex Factors; Smoking; Urin | 1981 |
The delta opioid receptor antagonist naltrindole attenuates both alcohol and saccharin intake in rats selectively bred for alcohol preference.
Topics: Alcohol Drinking; Animals; Drinking; Eating; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Inb | 1995 |
Suppression of ethanol intake in alcohol-preferring rats by prior voluntary saccharin consumption.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Depression, Chemical; Drinking; Eating; Male; Rats; S | 1995 |
Subcutaneous injections of the tachykinin senktide reduce alcohol intake in alcohol-preferring rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Choice Behavior; Drinking Behavior; Feeding Behavio | 1995 |
Saccharin-induced increase in daily fluid intake as a predictor of voluntary alcohol intake in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Drinking; Male; Rats; Rats, Inbred Strains; Saccharin; Species Specificit | 1995 |
Oral etonitazene and cocaine consumption by AA, ANA and Wistar rats.
Topics: Alcohol Drinking; Animals; Benzimidazoles; Citrates; Citric Acid; Cocaine; Male; Narcotics; Quinine; | 1993 |
Voluntary consumption of ethanol in 15 inbred mouse strains.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Male; Mice; Mice, Inbred Strains; Saccharin; Species S | 1993 |
Effects of stress and ebiratide (Hoe-427) on free-choice ethanol consumption: comparison of Lewis and Sprague-Dawley rats.
Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Analysis of Variance; Animals; Choice Behavior; Drink | 1994 |
Central and peripheral components of the inhibitory actions of 5-HTP on ethanol consumption in the rat.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Amidines; Animals; Central Nervous System; Conditioning, Oper | 1994 |
Saccharin intake predicts ethanol intake in genetically heterogeneous rats as well as different rat strains.
Topics: Alcohol Drinking; Animals; Arousal; Drinking; Genotype; Male; Rats; Rats, Inbred Strains; Saccharin; | 1993 |
Effects of chronic ethanol exposure on oral self-administration of ethanol or saccharin by Wistar rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Drug Tolerance; Ethanol; Male; Motivation; Rats; Rats, Wistar | 1996 |
The relationships among saccharin consumption, oral ethanol, and i.v. cocaine self-administration.
Topics: Alcohol Drinking; Animals; Cocaine; Conditioning, Operant; Food Deprivation; Injections, Intravenous | 1996 |
Role of taste aversion in calcium channel inhibitor-induced suppression of saccharin and alcohol drinking in rats.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Calcium Channel Blockers; Conditioning, Classical; Di | 1996 |
Effects of the benzodiazepine inverse agonist RO19-4603 alone and in combination with the benzodiazepine receptor antagonists flumazenil, ZK 93426 and CGS 8216, on ethanol intake in alcohol-preferring (P) rats.
Topics: Alcohol Drinking; Animals; Azepines; Benzodiazepines; Dose-Response Relationship, Drug; Drinking; Dr | 1996 |
Behavioral differences between two inbred strains of Fawn-Hooded rat: a model of serotonin dysfunction.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Behavior, Animal; Feeding Behavior; Rats; Rats, Inbre | 1996 |
Use of artificial sweeteners to promote alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Aspartame; Cyclamates; Drinking Behavior; Liver Cirrhosis, Alcoholic; Mal | 1997 |
Thyrotropin releasing hormone analog TA-0910 suppresses alcohol intake in alcohol drinking African green monkeys.
Topics: Alcohol Drinking; Animals; Chlorocebus aethiops; Drinking; Male; Motivation; Neurotransmitter Agents | 1997 |
Preference for saccharin-sweetened alcohol relative to isocaloric sucrose.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Ethanol; Food Preferences; Male; Rats; Rats, Wista | 1997 |
Fluoxetine reduces saccharin-induced elevation of fluid intake in alcohol-preferring Fawn-Hooded rats.
Topics: Alcohol Drinking; Animals; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Dru | 1997 |
Role of taste and calories in the selection of ethanol by C57BL/6NHsd and Hsd:ICR mice.
Topics: Alcohol Drinking; Animals; Aspartame; Behavior, Animal; Cacao; Energy Intake; Ethanol; Food Preferen | 1998 |
Serotonin3 receptor antagonism of alcohol intake: effects of drinking conditions.
Topics: Alcohol Drinking; Animals; Drinking; Drug Administration Schedule; Female; Indoles; Injections, Subc | 1998 |
Naltrexone and amperozide modify chocolate and saccharin drinking in high alcohol-preferring P rats.
Topics: Alcohol Drinking; Animals; Body Weight; Cacao; Dose-Response Relationship, Drug; Eating; Male; Naltr | 1998 |
Do taste factors contribute to the mediation of ethanol intake? Ethanol and saccharin-quinine intake in three rat strains.
Topics: Alcohol Drinking; Animals; Choice Behavior; Ethanol; Genotype; Male; Quinine; Rats; Rats, Inbred Lew | 1998 |
Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats.
Topics: Alcohol Drinking; Animals; Feeding Behavior; Male; Rats; Rats, Wistar; Saccharin; Social Isolation; | 1998 |
Effects of D1 dopamine receptor agonists on oral ethanol self-administration in rats: comparison with their efficacy to produce grooming and hyperactivity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Alcohol Drinking; | 1999 |
Operant self-administration of sweetened versus unsweetened ethanol: effects on blood alcohol levels.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Ethanol; Male; Rats; Rats, Wistar; Sa | 1999 |
Patterns of ethanol and saccharin intake in P rats under limited-access conditions.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Carcinogens; Central Nervous System Depressants; Ethano | 1999 |
Dissociation of ethanol and saccharin preference in sP and sNP rats.
Topics: Alcohol Drinking; Animals; Genotype; Male; Motivation; Rats; Rats, Inbred Strains; Saccharin; Taste | 2000 |
Differences in the consumption of ethanol and flavored solutions in three strains of rats.
Topics: Alcohol Drinking; Animals; Body Weight; Male; Quinine; Rats; Rats, Inbred Lew; Rats, Inbred WKY; Rat | 2000 |
Involvement of dopamine D2 autoreceptors in the ventral tegmental area on alcohol and saccharin intake of the alcohol-preferring P rat.
Topics: Alcohol Drinking; Animals; Dopamine Agonists; Dopamine Antagonists; Female; Rats; Receptors, Dopamin | 2000 |
Relative taste thresholds for ethanol, saccharin, and quinine solutions in three strains of rats nonselected for ethanol: a comparative study.
Topics: Alcohol Drinking; Animals; Body Weight; Central Nervous System Depressants; Drinking; Ethanol; Food | 2000 |
A comparison of the reinforcing efficacy of alcohol in alcohol-preferring (P) and alcohol-nonpreferring (NP) rats.
Topics: Alcohol Drinking; Animals; Ethanol; Glucans; Male; Rats; Rats, Inbred Strains; Reinforcement, Psycho | 2000 |
Animal model of ethanol abuse: rats selectively bred for high and low voluntary alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Disease Models, Animal; Rats; Rats, Wistar; Saccharin | 2000 |
Bidirectional changes in ethanol consumption in rats with site-specific antisense down-regulation of 5-hydroxytryptamine2A receptors in brain.
Topics: Alcohol Drinking; Amphetamines; Animals; Anxiety; Autoradiography; Brain Chemistry; Corticosterone; | 2001 |
Ethanol consumption and behavioral impulsivity are increased in protein kinase Cgamma null mutant mice.
Topics: Administration, Oral; Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Ethanol; Female; | 2001 |
Effects of naltrexone on the intake of ethanol and flavored solutions in rats.
Topics: Alcohol Drinking; Animals; Beverages; Drinking; Drug Combinations; Ethanol; Male; Naltrexone; Narcot | 2001 |
Intake of saccharin, salt, and ethanol solutions is increased by infusion of a mu opioid agonist into the nucleus accumbens.
Topics: Alcohol Drinking; Analgesics, Opioid; Animals; Central Nervous System Depressants; Ethanol; Feeding | 2002 |
Conditioned taste aversion and alcohol drinking: strain and gender differences.
Topics: Administration, Oral; Alcohol Drinking; Animals; Avoidance Learning; Central Nervous System Depressa | 2002 |
Mapping of QTL influencing saccharin consumption in the selectively bred alcohol-preferring and -nonpreferring rat lines.
Topics: Alcohol Drinking; Animals; Chromosome Mapping; Crosses, Genetic; Genotype; Phenotype; Quantitative T | 2002 |
Differences in ethanol-induced conditioned taste aversion in Sardinian alcohol-preferring and Sardinian alcohol-nonpreferring rats.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Choice Behavior; Conditioning, Psychological; Ethanol | 2002 |
Enduring effects of environmental enrichment on novelty seeking, saccharin and ethanol intake in two rat lines (RHA/Verh and RLA/Verh) differing in incentive-seeking behavior.
Topics: Alcohol Drinking; Animals; Environment; Ethanol; Exploratory Behavior; Male; Motivation; Rats; Sacch | 2002 |
Dietary caffeine and alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Caffeine; Drug Interactions; Male; Nutrition Disorders; Rats; Saccharin; | 1976 |
Effects of parachlorophenylalanine on ethanol self-selection in the rat.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Conditioning, Operant; Fenclonine; Male; Rats; Saccha | 1976 |
The effect of para-chlorophenylalanine on the intake of ethanol and saccharin solutions.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Feeding Behavior; Fenclonine; Male; Rats; Saccharin; S | 1977 |
Effects of crowding on alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Crowding; Female; Food Preferences; Humans; Milk; Rats; Saccharin; Stress | 1975 |
Free-choice ethanol intake and ethanol metabolism in the hamster and rat.
Topics: Alcohol Drinking; Alcohol Oxidoreductases; Animals; Cricetinae; Drinking Behavior; Ethanol; Liver; M | 1979 |
The temporal and volumetric components of stress induced drinking in rats.
Topics: Adaptation, Psychological; Alcohol Drinking; Animals; Drinking Behavior; Electroshock; Humans; Male; | 1977 |
Ethanol-induced taste aversion in ethanol-dependent and normal rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Avoidance Learning; Conditioning, Operant; Ethanol; Humans; M | 1979 |
Morphine preference of alcohol-avoiding and alcohol-preferring C57BL mice.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Genotype; Male; Mice; Mice, Inbred C57BL; Morphine; Sa | 1978 |
Polydipsic and home-cage fluid choices: the effects of sweetening.
Topics: Alcohol Drinking; Animals; Butylene Glycols; Drinking Behavior; Energy Intake; Food Deprivation; Mal | 1977 |
Shock induced ethanol consumption in rats.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Electroshock; Environment; Male; Rats; Saccharin; Stre | 1977 |
Shifts in the water and alcohol solution intake by rats under conditions of schedule induction.
Topics: Alcohol Drinking; Animals; Conditioning, Operant; Disease Models, Animal; Drinking Behavior; Ethanol | 1976 |
Effects of periodic withdrawal on ethanol and saccharin selection in rats.
Topics: Alcohol Drinking; Animals; Body Weight; Drinking Behavior; Food Preferences; Rats; Saccharin; Taste; | 1976 |
Effect of housing density on alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Drinking Behavior; Exploratory Behavior; Female; Humans | 1976 |
Alcohol-induced conditioned aversion: genotypie specificity in mice (Mus musculus).
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Oxidoreductases; Animals; Avoidance Learning; Conditioning, | 1975 |
Suppression of alcohol and saccharin preference in rats by a novel Ca2+ channel inhibitor, Goe 5438.
Topics: Alcohol Drinking; Animals; Appetite Depressants; Calcium Channel Blockers; Dose-Response Relationshi | 1992 |
The effect of Hoe-427 (an ACTH4-9 analog) on free-choice ethanol consumption in male and female rats.
Topics: Adrenocorticotropic Hormone; Alcohol Drinking; Animals; Drug Administration Schedule; Ethanol; Femal | 1991 |
Effects of weight restriction and palatability on the apparent pharmacological regulation of alcohol consumption by rats in a limited access paradigm.
Topics: Alcohol Drinking; Animals; Body Weight; Ethanol; Male; Rats; Rats, Inbred Strains; Saccharin; Weight | 1989 |
Differences in response to the aversive properties of ethanol in rats selectively bred for oral ethanol preference.
Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Psychological; Drinking Behavior; Ethanol; Fema | 1988 |
Bladder cancer and the consumption of alcoholic beverages in Spain.
Topics: Age Factors; Aged; Alcohol Drinking; Carcinoma, Transitional Cell; Cyclamates; Epidemiologic Methods | 1987 |
Effect of fennfluramine on alcohol and saccharin consumption in the rat.
Topics: Alcohol Drinking; Animals; Drinking Behavior; Fenclonine; Fenfluramine; Injections, Intraperitoneal; | 1972 |
A rat model of alcoholism?
Topics: Acetone; Alcohol Drinking; Alcoholism; Animal Nutritional Physiological Phenomena; Animals; Conditio | 1972 |
Enhancement of the consumption of acclimated sapid solutions following periodic and prolonged withdrawal.
Topics: Alcohol Drinking; Animals; Arousal; Avoidance Learning; Citrates; Drinking; Ethanol; Food Deprivatio | 1972 |
A new factor affecting the consumption of ethyl alcohol and other sapid fluids.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Circadian Rhythm; Drinking; Electric Stimulation; Eth | 1972 |
Effects of food deprivation and fluid sweetening on alcohol consumption by rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Ethanol; Food Deprivation; Male; Osmolar Concentration; | 1974 |
The effect of prior ethanol experience on ethanol-induced saccharin aversions.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Conditioning, Classical; Drug Tolerance; Ethanol; Mal | 1974 |
Lithium-induced suppression of alcohol drinking by rats.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Carbonates; Depression, Chemical; Drinking Behavior; Et | 1974 |
The role of olfactory and orosensory factors in the alcohol preference of inbred strains of mice.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Psychological; Cues; | 1971 |
Physical dependence on and tolerance to alcohol in the rat.
Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Drug Tolerance; Eth | 1971 |
Alcohol aversion in the rat: behavioral assessment of noxious drug effects.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Butyrates; Chlorine; Drug Antagonism; Oximes; Phenyla | 1970 |