sabinene has been researched along with Disease Models, Animal in 114 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 28 (24.56) | 29.6817 |
| 2010's | 56 (49.12) | 24.3611 |
| 2020's | 29 (25.44) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, H; Jung, SH; Kim, B; Kim, SJ; Lee, D; Lee, HM; Lee, KJ; Ryu, Y; Won, KJ | 1 |
| Chen, L; Dai, J; Fu, X; He, Q; Jiang, P; Kwan, HY; Liu, Y; Lou, L; Lu, H; Sun, X; Wang, M; You, Y; Zhao, X; Zhou, L; Zhou, X | 1 |
| Anpilogov, K; Beccari, T; Bertelli, M; Bhusan Tripathi, Y; Ceccarini, MR; Cecchin, S; Coatto, M; Dhuli, K; Donato, K; Michelini, S; Mishra, P; Pandey, N; Paolacci, S; Tripathi, P | 1 |
| Cha, MS; Jeon, S; Kim, MJ; Kim, Y; Kim, YJ; Park, SY; Yoon, HG | 1 |
| Chen, Q; Li, F; Li, H; Wang, F; Wang, L; Xu, J; Yang, M; Zhang, X | 1 |
| Chattopadhyay, N; Gayen, JR; Guha, R; Katekar, R; Kulkarni, C; Kumar, A; Kumar, N; Kumar, S; Pal, S; Porwal, K; Rajput, S; Sharma, S; Sihota, P; Singh, P; Tiwari, MC | 1 |
| Chu, X; Huai, Y; Huang, Q; Liang, X; Qian, A; Tian, Y; Wang, W; Wang, X; Yin, C; Zhao, Y | 1 |
| Chae, HJ; Chung, MJ; Kim, HJ; Lee, GH; Lee, J; Lee, YM; Park, JW; Shim, D; Yang, S | 1 |
| El-Maraghy, SA; Essam, RM; Kortam, MA; Reda, A | 1 |
| Ahn, KS; Jung, Y; Kim, HL; Kwak, HJ; Park, J; Um, JY | 1 |
| Chen, L; Li, JX; Li, M; Ma, ZC; Wu, JL | 1 |
| Gong, W; Guo, G; Li, F; She, J; Shi, F; Shi, W; Zhou, G | 1 |
| Ding, Z; Shu, Z; Wang, W; Wang, Y; Xia, T; Yang, Y; Zhao, H; Zhong, R | 1 |
| Amenta, M; Ariano, A; Ciarcia, R; Damiano, S; Florio, S; Giordano, A; Iovane, V; Mirabella, N; Prisco, F; Squillacioti, C | 1 |
| Furukawa, Y; Hara, RI; Nakajima, M; Nakaya, M; Okuyama, S; Sawamoto, A | 1 |
| Bwire, GM; Mloka, D; Nondo, RSO; Sangeda, RZ; Shija, KM | 1 |
| Amodio, N; Bedossa, P; Bosco, F; Caffrey, R; Carresi, C; Ehrlich, J; Gliozzi, M; Juli, G; Macrì, R; Maiuolo, J; Marioneaux, J; Mollace, R; Mollace, V; Muscoli, C; Musolino, V; Nucera, S; Palma, E; Ruga, S; Salvemini, D; Sanyal, AJ; Scarano, F; Scicchitano, M; Tassone, P; Walker, R; Zito, MC | 1 |
| Chae, HJ; Hoang, TH; Kang, SI; Kim, J; Lee, CH; Lee, GH; Lee, HY; Lee, JS; Park, SA; Peng, C | 1 |
| Chen, KC; Huang, BC; Lin, LY; Peng, RY | 1 |
| Cao, Y; Han, Y; Lan, Y; Li, F; Li, Z; Song, M; Wang, M; Wu, X; Xiao, H; Xiao, J; Zheng, J; Zhou, J | 1 |
| Chen, H; Huang, C; Ke, Z; Li, Y; Tan, S; Zhao, Y; Zhou, Z | 1 |
| Cao, Y; Chen, T; Chen, Y; Feng, K; Kan, Q; Liu, G; Zhu, X | 1 |
| Bastie, CC; Klein-Seetharaman, J; Tejpal, S; Wemyss, AM | 1 |
| Coutens, B; Etienne, P; Frances, B; Guiard, BP; Harster, A; Moulédous, L; Noirot, V; Rekik, K | 1 |
| Fujita, Y; Okuda, M; Sugimoto, H; Takada-Takatori, Y; Urakami, K | 1 |
| Fernández, J; Ferreira-Lazarte, A; Gallego-Lobillo, P; Lombó, F; Moreno, FJ; Villamiel, M; Villar, CJ | 1 |
| Chen, XY; Feng, FC; He, HL; Li, RF; Xu, Y; Zhou, XM | 1 |
| Furukawa, Y | 1 |
| Chen, Z; Cui, D; He, B; Jiang, J; Luo, M; Shi, Z; Wu, L; Xu, S; Yan, J; Yan, M; Zhang, S | 1 |
| Chen, M; Hu, W; Tian, X; Wang, W; Xie, L; Zhao, G; Zou, X | 1 |
| Bose, S; Kawai, G; Minamisawa, M; Suzuki, K; Suzumura, T; Taniai, T; Yamaguchi, A; Yamanaka, S | 1 |
| Furukawa, Y; Nakajima, M; Okuyama, S; Sawamoto, A | 1 |
| Chen, CW; Chen, YT; Dong, CD; Hou, CY; Hsieh, SL; Huang, YW; Leang, JY; Singhania, RR; Wu, CC | 1 |
| Hayashi, S; Kobayashi, H; Minatogawa, Y; Mitani, M; Nakamoto, M; Nii, Y; Sakai, T; Shuto, E | 1 |
| Bui, TT; Chai, OH; Kim, SM; Lee, CH; Piao, CH; Shin, HS; Song, CH | 1 |
| Afnan, K; Hasan, I; Hasan, N; Khan, S; Mohib, M; Paran, TZ; Sagor, AT; Sarker, J | 1 |
| Chen, Z; He, B; Hong, W; Jiang, J; Wu, L; Yan, M | 1 |
| Afroz, R; Das, S; Gan, SH; Hossain, MS; Hossen, MS; Ibrahim Khalil, M; Islam, MA; Paul, S; Saha, M; Tanvir, EM | 1 |
| Benavente-García, O; Castillo, J; Merola, N; Nieto, G; Ros, G | 1 |
| Chen, L; Chen, X; Dong, L; Kang, S; Lai, Y | 1 |
| Abe, H; Fujita, Y; Ishida, N; Ishioka, M; Nakajima, Y; Ohnishi, S; Sato, A; Shichiri, M; Suzuki, S; Umeno, A; Yasunaga, M; Yoshida, Y | 1 |
| Amakura, Y; Furukawa, Y; Mori, H; Nakajima, M; Ohkubo, Y; Okuyama, S; Sawamoto, A; Sudo, M; Sugawara, K; Tamanaha, A; Yamamoto, K; Yoshimura, M | 1 |
| Baradaran, S; Ghasemi-Kasman, M; Hajizadeh Moghaddam, A | 1 |
| Adebayo, AA; Ademosun, AO; Oboh, G | 1 |
| Chang, JH; Hong, J; Jeon, MT; Jung, UJ; Kim, DW; Kim, S; Kim, SR; Kwon, JY; Moon, GJ; Shin, M | 1 |
| Jaarin, K; Kamisah, Y; Mohamed, S; Siti, HN | 1 |
| Gao, X; Guo, S; Jiang, W; Liu, L; Shi, L; Tang, X; Yang, P; Zhang, S; Zhao, H | 1 |
| Goto, T; Inoue, E; Miyaguchi, Y; Sato, M; Toyoda, A | 1 |
| Caderni, G; Cirmi, S; Femia, AP; Ferlazzo, N; Luceri, C; Navarra, M; Romagnoli, A; Tortora, K | 1 |
| Furukawa, Y; Kanzaki, T; Katoh, M; Kotani, Y; Nakajima, M; Okuyama, S; Sawamoto, A | 1 |
| Bosco, F; Carresi, C; Colica, C; Gliozzi, M; Macrì, R; Maiuolo, J; Mollace, R; Mollace, V; Muscoli, C; Musolino, V; Nucera, S; Palma, E; Paone, S; Ragusa, S; Ruga, S; Scarano, F; Scicchitano, M; Zito, MC | 1 |
| Nakajima, A; Ohizumi, Y | 1 |
| Lee, HT; Lyu, JH | 1 |
| Franke, SI; Guecheva, TN; Henriques, JA; Prá, D | 1 |
| Badmaev, V; Ho, CT; Ho, MH; Lai, CS; Li, S; Pan, MH; Tsai, ML | 1 |
| Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA; Shin, TY | 1 |
| El-Shazly, AM; Hamdan, DI; Mahmoud, MF; Wink, M | 1 |
| Hiruma-Lima, CA; Kushima, H; Moraes, TM; Pellizzon, CH; Rocha, LR; Rozza, AL | 1 |
| Ferlazzo, N; Navarra, M; Russo, M; Schumacher, U; Ursino, MR; Valentiner, U | 1 |
| Abdel Moneim, AE; Al-Olayan, EM; El-Khadragy, MF | 1 |
| Alibabaei, Z; Deris, F; Mokhtari, S; Rabiei, Z; Rafieian-Kopaei, M; Rahnama, S | 1 |
| Iranshahi, M; Parhiz, H; Rezaee, R; Roohbakhsh, A; Soltani, F | 1 |
| Ahmad, A; Bruschetta, G; Campolo, M; Cuzzocrea, S; Di Paola, R; Esposito, E; Impellizzeri, D; Navarra, M | 1 |
| Ohizumi, Y | 1 |
| Kawahata, I; Yamakuni, T | 1 |
| Britti, D; Brunelli, E; Coscarelli, F; Costa, N; Ehrlich, J; Isidoro, C; Janda, E; Lascala, A; Mollace, V; Morittu, VM; Parafati, M; Rizzuto, A; Trimboli, F | 1 |
| Akram, K; Farooq, U; Hayat, Z; Shafi, A; Tanveer, A | 1 |
| Choi, BK; Jung, JY; Jung, WH; Kim, TW; Lee, DR; Lim, JH; Suh, JW; Yang, SH | 1 |
| Okuyama, S | 1 |
| Chung, HY; Li, MM; Li, YL; Liu, QY; Liu, Z; Tang, W; Wang, GC; Xu, JJ; Zhuang, L | 1 |
| Andrade, LN; Andreatini, R; de Almeida Soares Hocayen, P; de Sousa, DP | 1 |
| Bi, K; Chen, X; Shi, H; Xing, H; Zhang, K; Zhang, R | 1 |
| Cao, ZD; Li, JX; Shen, Q; Xiao, N; Zhou, XM | 1 |
| Gu, MJ; Im, M; Kim, A; Ma, JY | 1 |
| Amakura, Y; Furukawa, Y; Nakajima, M; Okuyama, S; Sawamoto, A; Yamamoto, K; Yoshimura, M | 1 |
| Chen, Q; Fan, S; Liu, X; Lu, Y; Wang, N; Yang, Y; Zheng, J; Zheng, X; Zhou, H; Zhu, Y | 1 |
| Ajdžanović, V; Jarić, I; Miler, M; Milošević, V; Šošić-Jurjević, B; Tanić, N; Živanović, J | 1 |
| Bakhiya, N; Dusemund, B; Hirsch-Ernst, KI; Lampen, A; Pevny, S; Richter, K; Schäfer, B; Schultrich, K; Ziegenhagen, R | 1 |
| Adeniyi, OS; Edino, VO; Omale, J; Omeje, SC | 1 |
| Matsuzaki, K; Mimaki, Y; Nakajima, A; Ogino, K; Ohizumi, Y; Onozuka, H; Saigusa, D; Sashida, Y; Shin, RW; Tetsu, N; Yamakuni, T; Yokosuka, A | 1 |
| Almeida, HL; Castro, LA; Rocha, NM; Sotto, MN | 1 |
| Aranganathan, S; Nalini, N; Selvam, JP | 1 |
| Bendele, P; Manthey, JA | 1 |
| Amado, M; de Almeida, HL; Jorge, VM | 1 |
| Huang, ZL; Liu, HY; Lu, WQ; Yang, GH; Yu, NR | 1 |
| Bai, F; Bai, G; Geng, P; Liu, Z; Shi, Q; Yang, Y; Zhang, Q; Zhu, YY | 1 |
| Li, P; Xu, L; Yang, ZL; Zhou, YQ | 1 |
| He, CC; Huang, MM; Li, JX; Zhou, XM | 1 |
| Kim, BK; Kim, SH; Lee, JC; Lee, YC; Ok, IS | 1 |
| Arora, B; Arora, R; Bali, M; Bansal, S; Gill, NS; Muthuraman, A; Sharma, PD; Sood, S | 1 |
| Su, M; Wang, Y; Yin, J; Zhang, H | 1 |
| Liu, QD; Mi, SQ; Ou, LJ; Sun, XP; Wang, NS | 1 |
| Gong, F; Shen, Y; Sun, Y; Tang, J; Tao, F; Xu, Q; Zhang, Q | 1 |
| Ahn, HJ; Cho, JJ; Gwak, C; Hong, SP; Kim, J; Kwon, HJ; Lee, KH; Lee, S; Park, CS; Park, YS; Ra, J; Song, JY; Yim, SV | 1 |
| Dogra, S; Kumar, A; Prakash, A | 1 |
| Bauab, TM; Hiruma-Lima, CA; Kushima, H; Marques, MO; Moraes, Tde M; Pellizzon, CH; Rozza, AL; Tanimoto, A | 1 |
| Campêlo, LM; Cerqueira, GS; de Almeida, AA; de Freitas, RL; de Freitas, RM; de Sousa, GF; Feitosa, CM; Saldanha, GB | 1 |
| Han, HS; Lee, J; Lim, SH; Song, KS; Yang, EJ | 1 |
| Hasunuma, R; Kawaguchi, K; Kikuchi, S; Kumazawa, Y; Maruyama, H; Ryll, R | 1 |
| Binnie, WH; Guo, IY; Hasegawa, S; Miller, EG; Porter, JL | 1 |
| Costa, M; Galindo, LA; Pultrini, Ade M | 1 |
| Amado, M; de Almeida, HL; Gonçalves, NE; Hallal, EC | 1 |
| Hamed, MA; Hetta, MH | 1 |
| Ogawa, K; Sugiura, M; Yano, M | 1 |
| Ainis, T; Bonaccorsi, I; Cavallaro, A; Contartese, G; Fimiani, V; Galati, EM; Taviano, MF; Tripodo, MM | 1 |
| Campbell, JI; Mortensen, A; Mølgaard, P | 1 |
| Deyhim, F; Garcia, M; Garica, K; Gonzalez, J; Ino, S; Lopez, E; Patil, BS | 1 |
| Au, K; Casaschi, A; Douglas, TD; Kurowska, EM; Li, RW; Mukherjee, R; Theriault, AG | 1 |
| Kawaguchi, K; Kometani, T; Kumazawa, Y; Maruyama, H | 1 |
| Chait, A; Elhabazi, K; Eljahiri, Y; Grases, F; Laroubi, A; Loubna, F; Oussama, A; Touhami, M; Zrara, I | 1 |
| Fujita, T; Fumuro, M; Gato, T; Iwaki, M; Kawase, A; Masuda, M; Matsuda, H; Sasaki, K; Shiura, T; Tokunaga, M; Utsunomiya, N | 1 |
| Grover, JK; Rathi, SS; Vats, V | 1 |
| Dancel, J; Hontz, BA; Liang, X; Proch, J; Sandone, N; Vinson, JA | 1 |
| Baekey, PA; Baumgartner, TG; Burgin, CW; Cerda, JJ; Rice, RW; Robbins, FL | 1 |
11 review(s) available for sabinene and Disease Models, Animal
| Article | Year |
|---|---|
[Search for Neuroprotective Compounds -From 4-Methycatechol to Citrus Compounds].
Topics: Animals; Catechols; Citrus; Cognitive Dysfunction; Coumarins; Disease Models, Animal; Drug Discovery; Female; Humans; Immunoenzyme Techniques; Male; Mice; Nerve Growth Factor; Neuroprotective Agents; Phytotherapy; Rats | 2021 |
[The Search for Citrus Components with Neuroprotective and Anti-dementia Effects in the Mouse Brain].
Topics: Animals; Anti-Inflammatory Agents; Brain Ischemia; Cell Death; Citrus; Dementia; Disease Models, Animal; Flavonoids; Hippocampus; Memory Disorders; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Nootropic Agents; Phytotherapy; tau Proteins | 2021 |
Beneficial Role of Citrus Fruit Polyphenols Against Hepatic Dysfunctions: A Review.
Topics: Animals; Biomarkers; Citrus; Clinical Trials as Topic; Cytokines; Disease Models, Animal; Humans; Liver; Liver Diseases; Metabolic Syndrome; Mitochondria; Oxidative Stress; Polyphenols | 2018 |
Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Biomarkers; Citrus; Disease Models, Animal; Drug Evaluation, Preclinical; Flavones; Flavonoids; Humans; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Signal Transduction | 2019 |
Orange juice and cancer chemoprevention.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Beverages; Chemoprevention; Citrus; Cytoprotection; Disease Models, Animal; DNA Damage; Fruit; Humans; Neoplasms; Phytoestrogens; Randomized Controlled Trials as Topic | 2013 |
Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: an updated review of their molecular mechanisms and experimental models.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Citrus; Disease Models, Animal; Hesperidin; Humans; Inflammation; NF-kappa B; Oxidative Stress; Signal Transduction | 2015 |
[A new strategy for preventive and functional therapeutic methods for dementia--approach using natural products].
Topics: Animals; Biological Products; Citrus; Dementia; Diet; Disease Models, Animal; Functional Food; Humans | 2015 |
Management of diabetic complications through fruit flavonoids as a natural remedy.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biological Availability; Carica; Citrus; Diabetes Complications; Diabetes Mellitus, Type 2; Diospyros; Disease Models, Animal; Flavonoids; Fruit; Humans; Hypoglycemic Agents; Insulin; Pancreas; Phytotherapy; Plant Extracts; Psidium | 2017 |
[Effects of Bioactive Substances from Citrus on the Central Nervous System and Utilization as Food Material].
Topics: Animals; Anti-Inflammatory Agents; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Central Nervous System; Citrus; Coumarins; Cyclooxygenase 2; Disease Models, Animal; Flavones; Food; Hippocampus; Humans; Memory Disorders; Mice; Microglia; Nervous System Diseases; Neurogenesis; Neuroprotective Agents; Phytotherapy; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2015 |
A Systematic Review of the Anxiolytic-Like Effects of Essential Oils in Animal Models.
Topics: Achillea; Alpinia; Animals; Anti-Anxiety Agents; Anxiety; Citrus; Controlled Clinical Trials as Topic; Disease Models, Animal; Humans; Lavandula; Maze Learning; Mice; Oils, Volatile; Plant Oils; Rats | 2015 |
Phytochemical compounds in sport nutrition: Synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks.
Topics: Animals; Citrates; Citrus; Dietary Supplements; Disease Models, Animal; Fruit; Humans; Phytochemicals; Plant Extracts; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Sports Nutritional Physiological Phenomena; Synephrine | 2017 |
103 other study(ies) available for sabinene and Disease Models, Animal
| Article | Year |
|---|---|
Sabinene Prevents Skeletal Muscle Atrophy by Inhibiting the MAPK-MuRF-1 Pathway in Rats.
Topics: Animals; Bicyclic Monoterpenes; Cell Survival; Disease Models, Animal; Male; Mitogen-Activated Protein Kinases; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myoblasts; Rats; Reactive Oxygen Species; Signal Transduction; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2019 |
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Biomarkers; Chromatography, High Pressure Liquid; Citrus; Diet, High-Fat; Disease Models, Animal; Disease Susceptibility; Glucose Tolerance Test; Glycolipids; Inflammation Mediators; Lipid Metabolism; Male; Metabolic Diseases; Mice; Plant Extracts; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2021 |
Effect of a dietary supplement on the reduction of lymphedema-progression in mouse tail-cut model.
Topics: Animals; Citrus; Dietary Supplements; Disease Models, Animal; Disease Progression; Lymphedema; Mice; Olea; Oryza; Phenylethyl Alcohol; Plant Extracts; Tail; Treatment Outcome; Vitamin A; Wound Healing | 2021 |
Beneficial Effects of a Combination of
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Citrus; Curcuma; Disease Models, Animal; Mice; Peptide Fragments; Plant Extracts | 2022 |
Transdermal Administration of Volatile Oil from
Topics: Administration, Cutaneous; Animals; Citrus; Constipation; Disease Models, Animal; Gastrointestinal Microbiome; Metabolomics; Oils, Volatile; Rats; Rats, Sprague-Dawley | 2022 |
Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the renal function.
Topics: Animals; Bone Density; Cancellous Bone; Citrus; Diosmin; Disease Models, Animal; Female; Flavonoids; Osteoporosis; Phytotherapy; Protective Agents; Rats; Renal Insufficiency, Chronic | 2022 |
Bergamottin promotes osteoblast differentiation and bone formation
Topics: Animals; Cell Proliferation; Cells, Cultured; Citrus; Disease Models, Animal; Female; Furocoumarins; Humans; Mice; Osteoblasts; Osteogenesis; Osteoporosis, Postmenopausal; Ovariectomy; Wnt Signaling Pathway | 2022 |
Topics: Animals; Asthma; Citrus; COVID-19; Disease Models, Animal; Humans; Immunity; Lung; Mice; Pandemics; Plant Extracts; Pneumonia | 2022 |
The citrus flavonoid "Nobiletin" impedes STZ-induced Alzheimer's disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Autophagy; Citrus; Disease Models, Animal; Flavonoids; Mice; Sirtuin 1 | 2023 |
Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Adipogenesis; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Citrus; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Male; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Signal Transduction; Thermogenesis | 2019 |
Effect of lemon water soluble extract on hyperuricemia in a mouse model.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Citrus; Disease Models, Animal; Fruit; Glucose Transport Proteins, Facilitative; Humans; Hyperuricemia; Male; Mice; Plant Extracts; Potassium Citrate; Uric Acid | 2019 |
Anti-inflammatory effects of eriocitrin against the dextran sulfate sodium-induced experimental colitis in murine model.
Topics: Animals; Anti-Inflammatory Agents; Citrus; Colitis; Colon; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Models, Animal; Flavanones; Inflammation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide Synthase Type II; Peroxidase; Plant Extracts; Severity of Illness Index; Weight Loss | 2019 |
Cardioprotective effects of a Fructus Aurantii polysaccharide in isoproterenol-induced myocardial ischemic rats.
Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Cardiotonic Agents; Citrus; Disease Models, Animal; Isoproterenol; Male; Myocardial Ischemia; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinases; Plant Extracts; Polysaccharides; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Red orange and lemon extract prevents the renal toxicity induced by ochratoxin A in rats.
Topics: Animals; Citrus; Citrus sinensis; Disease Models, Animal; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Ochratoxins; Plant Extracts; Rats; Renal Insufficiency | 2020 |
Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells.
Topics: Animals; Anti-Inflammatory Agents; Brain; Cell Line, Tumor; Cell Survival; Citrus; Coumarins; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Glial Cell Line-Derived Neurotrophic Factor; Glioma; Mice; Nerve Growth Factors; Neuroprotective Agents; Phosphorylation; Rats; RNA, Messenger; Signal Transduction | 2019 |
Effects of lemon decoction on malaria parasite clearance and selected hematological parameters in Plasmodium berghei ANKA infected mice.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Citrus; Disease Models, Animal; Drug Therapy, Combination; Female; Malaria; Male; Mice; Parasitemia; Plant Extracts; Plasmodium berghei; Tanzania | 2020 |
Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease.
Topics: Animals; Citrus; Diet, Western; Disease Models, Animal; Dyslipidemias; Gene Expression; Humans; Inflammation; MAP Kinase Kinase 4; Mice; Non-alcoholic Fatty Liver Disease; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Polyphenols | 2020 |
Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling.
Topics: AMP-Activated Protein Kinases; Animals; Citrus; Diet, High-Fat; Disease Models, Animal; Endoplasmic Reticulum; Freeze Drying; Humans; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Plant Extracts; Rats; Reactive Oxygen Species; Signal Transduction | 2020 |
Integrated anti-hyperlipidemic bioactivity of whole Citrus grandis [L.] osbeck fruits-multi-action mechanism evidenced using animal and cell models.
Topics: Animals; Cell Line; Citrus; Disease Models, Animal; Fruit; Functional Food; Humans; Hyperlipidemias; Hypolipidemic Agents; Phytotherapy; Rats; Rats, Wistar; Taiwan | 2020 |
The chemopreventive effect of 5-demethylnobiletin, a unique citrus flavonoid, on colitis-driven colorectal carcinogenesis in mice is associated with its colonic metabolites.
Topics: Animals; Anticarcinogenic Agents; Citrus; Colitis; Colorectal Neoplasms; Disease Models, Animal; Flavones; Flavonoids; Male; Mice; Mice, Inbred Strains | 2020 |
Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice.
Topics: Animals; Choline; Citrus; Diet, High-Fat; Disease Models, Animal; Fruit; Humans; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; NF-E2 Transcription Factor; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Plant Extracts | 2020 |
Dietary citrus peel essential oil ameliorates hypercholesterolemia and hepatic steatosis by modulating lipid and cholesterol homeostasis.
Topics: Animals; Biomarkers; Cholesterol; Citrus; Dietary Fats, Unsaturated; Dietary Supplements; Disease Models, Animal; Homeostasis; Hypercholesterolemia; Lipidomics; Lipids; Lipogenesis; Liver; Male; Non-alcoholic Fatty Liver Disease; Oils, Volatile; Rats; Rats, Sprague-Dawley | 2020 |
Lemon Extract Reduces Angiotensin Converting Enzyme (ACE) Expression and Activity and Increases Insulin Sensitivity and Lipolysis in Mouse Adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Differentiation; Citrus; Disease Models, Animal; Glucose Transporter Type 4; Insulin; Insulin Resistance; Lipid Metabolism; Lipolysis; Mice; Peptidyl-Dipeptidase A; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Sterol Esterase | 2020 |
A Citrus Based Sensory Functional Food Ingredient Induces Antidepressant-like Effects: Possible Involvement of an Interplay between the Olfactory and the Serotonergic Systems.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Citrus; Depression; Disease Models, Animal; Food Ingredients; Mice; Smell | 2020 |
Aromatherapy improves cognitive dysfunction in senescence-accelerated mouse prone 8 by reducing the level of amyloid beta and tau phosphorylation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aromatherapy; Brain; Brain-Derived Neurotrophic Factor; Citrus; Cognitive Dysfunction; Disease Models, Animal; Down-Regulation; Humans; Male; Maze Learning; Mice; Oils, Volatile; Phosphorylation; Plant Oils; tau Proteins; Treatment Outcome | 2020 |
Behaviour of citrus pectin and modified citrus pectin in an azoxymethane/dextran sodium sulfate (AOM/DSS)-induced rat colorectal carcinogenesis model.
Topics: Acetates; Animals; Azoxymethane; Bifidobacterium; Blood Glucose; Body Weight; Butyrates; Carcinogenesis; Chromatography, High Pressure Liquid; Citrus; Colorectal Neoplasms; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Hydrogen-Ion Concentration; Lactic Acid; Lactobacillaceae; Male; Metagenomics; Pectins; Phylogeny; Propionates; Proteobacteria; Rats; Rats, Inbred F344; Triglycerides | 2021 |
Inhibitory effects of alkaline extract from the pericarp of Citrus reticulata Blanco on collagen behavior in bleomycin-induced pulmonary fibrosis.
Topics: Administration, Oral; Alkalies; Amino Acid Oxidoreductases; Amino Acids; Animals; Bleomycin; Citrus; Collagen Type I; Collagen Type III; Disease Models, Animal; Down-Regulation; Extracellular Matrix Proteins; Hydroxyproline; Mice, Inbred C57BL; Plant Extracts; Protein-Lysine 6-Oxidase; Pulmonary Fibrosis; Smad3 Protein; Transforming Growth Factor beta1 | 2021 |
Pure total flavonoids from citrus attenuate non-alcoholic steatohepatitis via regulating the gut microbiota and bile acid metabolism in mice.
Topics: Animals; Bacteria; Bile Acids and Salts; Citrus; Diet, High-Fat; Disease Models, Animal; Dysbiosis; Flavonoids; Gastrointestinal Microbiome; Intestines; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Plant Extracts; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Signal Transduction | 2021 |
Pomelo peel oil suppresses TNF-α-induced necroptosis and cerebral ischaemia-reperfusion injury in a rat model of cardiac arrest.
Topics: Animals; Citrus; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Arrest; Male; Necroptosis; Neuroprotective Agents; Oils, Volatile; Plant Oils; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Rate; Tumor Necrosis Factor-alpha | 2021 |
Effect of Yuzu (
Topics: Animals; Citrus; Disease Models, Animal; Gastrointestinal Microbiome; Limonins; Mice; RNA, Ribosomal, 16S; Sandhoff Disease; Spermine | 2021 |
The Anti-Obesity Effects of Lemon Fermented Products in 3T3-L1 Preadipocytes and in a Rat Model with High-Calorie Diet-Induced Obesity.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Citrus; Diet, High-Fat; Disease Models, Animal; Fermentation; Lipid Metabolism; Male; Mice; Obesity; Plant Preparations; Rats; Rats, Wistar | 2021 |
Extracts of citrus Sudachi peel attenuate body weight gain in C57BL/6 mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Blood Glucose; Citrus; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; RNA, Messenger; Tumor Necrosis Factor-alpha; Weight Gain | 2017 |
Citrus tachibana Leaves Ethanol Extract Alleviates Airway Inflammation by the Modulation of Th1/Th2 Imbalance via Inhibiting NF-κB Signaling and Histamine Secretion in a Mouse Model of Allergic Asthma.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Citrus; Disease Models, Animal; Histamine; Humans; Immunoglobulin E; Interleukin-12; Interleukin-6; Mice; NF-kappa B; Plant Extracts; Th1 Cells; Th2 Cells | 2017 |
Pure total flavonoids from citrus improve non-alcoholic fatty liver disease by regulating TLR/CCL signaling pathway: A preliminary high-throughput 'omics' study.
Topics: Animals; Chemokines, CC; Citrus; Diet, High-Fat; Disease Models, Animal; Flavonoids; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; RNA, Messenger; Signal Transduction; Toll-Like Receptors | 2017 |
Protective effects of ethanolic peel and pulp extracts of Citrus macroptera fruit against isoproterenol-induced myocardial infarction in rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Citrus; Disease Models, Animal; Fruit; Isoproterenol; Male; Myocardial Infarction; Oxidative Stress; Plant Extracts; Rats, Wistar | 2017 |
The Effect of Consumption of Citrus Fruit and Olive Leaf Extract on Lipid Metabolism.
Topics: Animals; Anti-Obesity Agents; Biomarkers; Cholesterol; Citrus; Diet, High-Fat; Disease Models, Animal; Feces; Fruit; Lactones; Lipase; Lipid Metabolism; Lipids; Lipoproteins, LDL; Male; Obesity; Olea; Orlistat; Plant Extracts; Plant Leaves; Postprandial Period; Rats, Wistar; Time Factors; Triglycerides | 2017 |
Polysaccharides from Citrus grandis L. Osbeck suppress inflammation and relieve chronic pharyngitis.
Topics: Ammonia; Animals; Citrus; Cytokines; Disease Models, Animal; HEK293 Cells; Humans; I-kappa B Kinase; Inflammation; Interferon-gamma; Interleukin-2; Interleukin-4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pharyngitis; Phosphorylation; Plant Extracts; Polysaccharides; Rabbits; T-Lymphocytes | 2017 |
Yuzu (Citrus junos Tanaka) Peel Attenuates Dextran Sulfate Sodium-induced Murine Experimental Colitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Citrus; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Macrophages; Male; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; Phytotherapy; Plant Extracts; Tumor Necrosis Factor-alpha | 2018 |
Neuroprotective effect of Citrus kawachiensis (Kawachi Bankan) peels, a rich source of naringin, against global cerebral ischemia/reperfusion injury in mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Astrocytes; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Death; Citrus; Constriction, Pathologic; Disease Models, Animal; Flavanones; Glutathione; Hippocampus; Inflammation; Male; Mice, Inbred C57BL; Microglia; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphorylation; Plant Extracts; Plant Structures; Reperfusion Injury | 2018 |
Hesperetin reduces myelin damage and ameliorates glial activation in lysolecithin-induced focal demyelination model of rat optic chiasm.
Topics: Animals; Antioxidants; Citrus; Demyelinating Diseases; Disease Models, Animal; Evoked Potentials, Visual; Hesperidin; Lysophosphatidylcholines; Male; Multiple Sclerosis; Myelin Sheath; Neuroglia; Optic Chiasm; Rats; Rats, Wistar | 2018 |
Modulatory effect of some citrus (Citrus limon, Citrus reticulata, Citrus maxima) peels on monoamine oxidase, phosphodiesterase-5 and angiotensin-1 converting enzyme activities in rat heart homogenate.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Antioxidants; Citrus; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Fruit; Male; Monoamine Oxidase; Myocardium; Plant Extracts; Rats | 2018 |
Beneficial Effects of Hesperetin in a Mouse Model of Temporal Lobe Epilepsy.
Topics: Administration, Oral; Animals; Anticonvulsants; Citrus; Disease Models, Animal; Epilepsy, Temporal Lobe; Fruit; Hesperidin; Kainic Acid; Male; Mice; Phytotherapy | 2018 |
Effects of citrus leaf extract on aortic vascular reactivity in hypertensive rats fed repeatedly heated vegetable oil.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Citrus; Cooking; Disease Models, Animal; Hot Temperature; Hypertension; Male; Nitric Oxide; Nitrites; Palm Oil; Phenylephrine; Plant Extracts; Plant Leaves; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2019 |
Pharmacokinetics and pharmacodynamics of citrus peel extract in lipopolysaccharide-induced acute lung injury combined with Pinelliae Rhizoma Praeparatum.
Topics: Acute Lung Injury; Animals; Citrus; Disease Models, Animal; Drugs, Chinese Herbal; Fruit; Lipopolysaccharides; Male; Pinellia; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sitosterols | 2018 |
Dietary Intake of Immature Citrus tumida Hort. ex Tanaka Peels Suppressed Body Weight Gain and Fat Accumulation in a Mouse Model of Acute Obesity.
Topics: Acute Disease; Adiposity; Animals; Anti-Obesity Agents; Cholesterol; Citrus; Diet; Diet, High-Fat; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Triglycerides; Weight Gain | 2019 |
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apc
Topics: Animals; Citrus; Colorectal Neoplasms; Disease Models, Animal; Flavonoids; Fruit and Vegetable Juices; Male; Models, Genetic; Plant Extracts; Rats; Rats, Inbred F344 | 2020 |
Continual Treatment with the Peels of Citrus kawachiensis (Kawachi Bankan) Protects against Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's Disease.
Topics: Animals; Body Weight; Cell Death; Citrus; Disease Models, Animal; Fruit; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Parkinson Disease; Plant Extracts | 2019 |
The effect of bergamot polyphenolic fraction on lipid transfer protein system and vascular oxidative stress in a rat model of hyperlipemia.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Carrier Proteins; Citrus; Diet, High-Fat; Disease Models, Animal; Hyperlipidemias; Lipoproteins, LDL; Liver; Male; Oxidative Stress; Polyphenols; Rats, Wistar | 2019 |
Effects of dried Citrus unshiu peels on gastrointestinal motility in rodents.
Topics: Administration, Oral; Animals; Citrus; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Gastrointestinal Agents; Gastrointestinal Transit; Ileus; Male; Medicine, Korean Traditional; Mice; Mice, Inbred ICR; Plant Extracts; Rats; Rats, Sprague-Dawley | 2013 |
Suppression of adipogenesis and obesity in high-fat induced mouse model by hydroxylated polymethoxyflavones.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Citrus; Diet, High-Fat; Disease Models, Animal; Down-Regulation; Flavones; Fruit; Humans; Male; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; PPAR gamma | 2013 |
The antiallergic mechanisms of Citrus sunki and bamboo salt (K-ALL) in an allergic rhinitis model.
Topics: Administration, Intranasal; Administration, Oral; Anaphylaxis; Animals; Calcimycin; Calcium Ionophores; Carcinogens; Cell Line; Citrus; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Male; Mast Cells; Medicine, Korean Traditional; Mice; Mice, Inbred ICR; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Tetradecanoylphorbol Acetate | 2014 |
Hepatoprotective effect of limonin, a natural limonoid from the seed of Citrus aurantium var. bigaradia, on D-galactosamine-induced liver injury in rats.
Topics: Administration, Oral; Animals; Citrus; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Inflammation; Limonins; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Seeds; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Healing actions of essential oils from Citrus aurantium and d-limonene in the gastric mucosa: the roles of VEGF, PCNA, and COX-2 in cell proliferation.
Topics: Animals; Cell Proliferation; Citrus; Cyclohexenes; Cyclooxygenase 2; Disease Models, Animal; Gastric Mucosa; Limonene; Male; Oils, Volatile; Plant Oils; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Stomach Ulcer; Terpenes; Vascular Endothelial Growth Factor A | 2013 |
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.
Topics: Animals; Beverages; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Citrus; Disease Models, Animal; Female; Flavonoids; Fruit; Heterografts; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Neuroblastoma | 2014 |
Neuroprotective effects of Citrus reticulata in scopolamine-induced dementia oxidative stress in rats.
Topics: Acetylcholinesterase; Animals; Cerebral Cortex; Citrus; Corpus Striatum; Dementia; Disease Models, Animal; Dopamine; Fruit; Glutathione; Hippocampus; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide; Norepinephrine; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Scopolamine; Serotonin | 2014 |
Anti-amnesic activity of Citrus aurantium flowers extract against scopolamine-induced memory impairments in rats.
Topics: Acetylcholinesterase; Analysis of Variance; Animals; Antioxidants; Avoidance Learning; Brain; Cholinergic Antagonists; Citrus; Disease Models, Animal; Dose-Response Relationship, Drug; Ferric Compounds; Flowers; Male; Malondialdehyde; Memory Disorders; Plant Extracts; Rats; Reaction Time; Scopolamine; Spatial Learning | 2015 |
The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Benzenesulfonates; Beverages; Citrus; Colitis; Colon; Disease Models, Animal; Inflammatory Bowel Diseases; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Mice; Neutrophil Infiltration; NF-kappa B; P-Selectin; Peroxidase; Plant Extracts; Poly Adenosine Diphosphate Ribose; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2015 |
[Pharmacological superiority of nobiletin-rich Citrus reticulata peel, a multicomponent drug, over nobiletin alone regarding anti-dementia action].
Topics: Animals; Citrus; Dementia; Disease Models, Animal; Dizocilpine Maleate; Flavones; Humans; Mice; Phytotherapy | 2015 |
Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome.
Topics: Animals; Anti-Obesity Agents; Autophagy; Biomarkers; Citrus; Diet, Western; Dietary Supplements; Disease Models, Animal; Fruit; Humans; Italy; Lipid Droplets; Lipotropic Agents; Liver; Metabolic Syndrome; Microtubule-Associated Proteins; Non-alcoholic Fatty Liver Disease; Obesity; Plant Extracts; Polyphenols; Random Allocation; Rats, Wistar; Ultrasonography | 2015 |
A polymethoxy flavonoids-rich Citrus aurantium extract ameliorates ethanol-induced liver injury through modulation of AMPK and Nrf2-related signals in a binge drinking mouse model.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Binge Drinking; Citrus; Disease Models, Animal; Ethanol; Flavones; Flavonoids; Heme Oxygenase-1; Inflammation; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Plant Extracts; Silymarin; Tumor Necrosis Factor-alpha | 2015 |
Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo.
Topics: Animals; Antiviral Agents; Citrus; Disease Models, Animal; Flavones; Humans; Lung; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Virus Replication | 2015 |
Antidepressant-like effect of the water extract of the fixed combination of Gardenia jasminoides, Citrus aurantium and Magnolia officinalis in a rat model of chronic unpredictable mild stress.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Citrus; Corticosterone; Depression; Disease Models, Animal; Doublecortin Protein; Drugs, Chinese Herbal; Fruit; Gardenia; Hippocampus; Hypothalamo-Hypophyseal System; Iridoids; Magnolia; Male; Molecular Structure; Neurogenesis; Pituitary-Adrenal System; Plant Bark; Plant Extracts; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2015 |
Inhibitory effects of amines from Citrus reticulata on bleomycin-induced pulmonary fibrosis in rats.
Topics: Amines; Animals; Bleomycin; China; Citrus; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Humans; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2016 |
Citrus unshiu peel extract alleviates cancer-induced weight loss in mice bearing CT-26 adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cell Line; Cell Survival; Citrus; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hemoglobins; Humans; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Muscle Proteins; Muscle, Skeletal; Nitric Oxide Synthase Type II; Plant Extracts; SKP Cullin F-Box Protein Ligases; Transplantation, Heterologous; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Weight Loss | 2016 |
3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus.
Topics: Animals; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Citrus; Corticosterone; Depression; Disease Models, Animal; Flavonoids; Gene Expression Regulation; Hippocampus; Male; Mice; Neurogenesis; Neuronal Plasticity | 2016 |
The citrus flavonoid naringenin confers protection in a murine endotoxaemia model through AMPK-ATF3-dependent negative regulation of the TLR4 signalling pathway.
Topics: Activating Transcription Factor 3; AMP-Activated Protein Kinases; Animals; Citrus; Disease Models, Animal; Endotoxemia; Flavanones; Lipopolysaccharides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Toll-Like Receptor 4 | 2016 |
Citrus flavanones mildly interfere with pituitary-thyroid axis in old-aged male rats.
Topics: Age Factors; Animals; Citrus; Disease Models, Animal; Flavanones; Gene Expression Regulation; Hormones; Hypothalamo-Hypophyseal System; Immunohistochemistry; Male; Pituitary Gland; Rats; Rats, Wistar; Thyroid Gland | 2017 |
Antidiarrheal activity of hexane extract of Citrus limon peel in an experimental animal model.
Topics: Animals; Antidiarrheals; Citrus; Diarrhea; Disease Models, Animal; Gastrointestinal Motility; Male; Plant Extracts; Rats; Rats, Wistar | 2017 |
Nobiletin, a citrus flavonoid, improves memory impairment and Abeta pathology in a transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Citrus; Disease Models, Animal; Flavones; Flavonoids; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2008 |
Transmission electron microscopy of the preclinical phase of experimental phytophotodermatitis.
Topics: Animals; Blister; Citrus; Dermatitis, Phototoxic; Desmosomes; Disease Models, Animal; Epidermis; Erythema; Fruit; Microscopy, Electron, Transmission; Necrosis; Rats | 2008 |
Effect of hesperetin, a citrus flavonoid, on bacterial enzymes and carcinogen-induced aberrant crypt foci in colon cancer rats: a dose-dependent study.
Topics: 1,2-Dimethylhydrazine; Animals; Bacteria; Body Weight; Carcinogens; Cell Transformation, Neoplastic; Citrus; Colon; Colonic Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Feces; Flavanones; Hesperidin; Injections, Subcutaneous; Intestinal Mucosa; Male; Phytotherapy; Precancerous Conditions; Rats; Rats, Wistar | 2008 |
Anti-inflammatory activity of an orange peel polymethoxylated flavone, 3',4',3,5,6,7,8-heptamethoxyflavone, in the rat carrageenan/paw edema and mouse lipopolysaccharide-challenge assays.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Citrus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Flavonoids; Humans; Inflammation; Lipopolysaccharides; Male; Mice; Plant Extracts; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2008 |
Serial light microscopy of experimental phytophotodermatitis in animal model.
Topics: Animals; Blister; Citrus; Disease Models, Animal; Erythema; Fruit; Humans; Keratinocytes; Light; Necrosis; Photosensitivity Disorders; Rats; Time Factors | 2009 |
Inhibitory effect of modified citrus pectin on liver metastases in a mouse colon cancer model.
Topics: Animals; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Citrus; Colonic Neoplasms; Disease Models, Animal; Female; Galectin 3; Liver Neoplasms; Mice; Mice, Inbred BALB C; Pectins; Phytotherapy; Plant Extracts; Splenic Neoplasms | 2008 |
Identification of anti-asthmatic compounds in Pericarpium citri reticulatae and evaluation of their synergistic effects.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Anti-Asthmatic Agents; Asthma; CHO Cells; Citrus; Cough; Cricetinae; Cricetulus; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Female; Guinea Pigs; In Vitro Techniques; Plant Extracts; Proline; Synephrine | 2009 |
Modulating effect of Hesperidin on experimental murine colitis induced by dextran sulfate sodium.
Topics: Animals; Citrus; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Hesperidin; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Organ Size; Peroxidase; Phytotherapy; Plant Extracts | 2009 |
Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis.
Topics: Animals; Bleomycin; Body Weight; Cell Survival; Cells, Cultured; Citrus; Disease Models, Animal; Drugs, Chinese Herbal; Hydroxyproline; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2009 |
Pinellia ternata, Citrus reticulata, and their combinational prescription inhibit eosinophil infiltration and airway hyperresponsiveness by suppressing CCR3+ and Th2 cytokines production in the ovalbumin-induced asthma model.
Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Cells, Cultured; Citrus; Disease Models, Animal; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Interleukin-13; Interleukin-4; Interleukin-5; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Pinellia; Plant Extracts; Polymerase Chain Reaction; Receptors, CCR3; Th2 Cells | 2009 |
Antioxidant, anti-inflammatory and analgesic potential of the Citrus decumana L. peel extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Citrus; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Male; Mice; Morphine; Pain; Plant Extracts; Rats; Rats, Wistar; Solvents | 2009 |
[Effect of nobiletin on K562 cells xenograft in nude mice].
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Citrus; Disease Models, Animal; Flavones; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Transplantation, Heterologous; Vascular Endothelial Growth Factors | 2009 |
[Effects of Rhizoma zingiberis and Pericarpium citri reticulatae extracts on myocardial ischemia in rats].
Topics: Acute Disease; Animals; Antioxidants; Citrus; Creatine Kinase; Disease Models, Animal; Drugs, Chinese Herbal; Electrocardiography; Hemorheology; Lactate Dehydrogenases; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardium; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Zingiberaceae | 2009 |
Obaculactone suppresses Th1 effector cell function through down-regulation of T-bet and prolongs skin graft survival in mice.
Topics: Animals; Chromatography, High Pressure Liquid; Citrus; Disease Models, Animal; Down-Regulation; Forkhead Transcription Factors; Graft Survival; Interferon-gamma; Limonins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Plant Extracts; Receptors, IgG; Skin Transplantation; Spleen; T-Box Domain Proteins; T-Lymphocytes, Regulatory; Th1 Cells; Transplantation, Homologous | 2010 |
Extracts from Citrus unshiu promote immune-mediated inhibition of tumor growth in a murine renal cell carcinoma model.
Topics: Animals; Carcinoma, Renal Cell; Cell Division; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Kidney Neoplasms; Lymphocytes; Mice; Mice, Inbred BALB C; Plant Extracts; Spleen | 2011 |
Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats.
Topics: Alzheimer Disease; Animals; Citrus; Cognition; Colchicine; Disease Models, Animal; Flavanones; Flavonoids; Humans; Male; Maze Learning; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar | 2010 |
Gastroprotective mechanisms of Citrus lemon (Rutaceae) essential oil and its majority compounds limonene and β-pinene: involvement of heat-shock protein-70, vasoactive intestinal peptide, glutathione, sulfhydryl compounds, nitric oxide and prostaglandin E
Topics: Animals; Bicyclic Monoterpenes; Bridged Bicyclo Compounds; Citrus; Cyclohexenes; Dinoprostone; Disease Models, Animal; Drug Synergism; Glutathione; Helicobacter Infections; Helicobacter pylori; HSP70 Heat-Shock Proteins; Immunohistochemistry; Limonene; Male; Microbial Sensitivity Tests; Monoterpenes; Nitric Oxide; Plant Oils; Protective Agents; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Terpenes; Vasoactive Intestinal Peptide | 2011 |
Antioxidant and antinociceptive effects of Citrus limon essential oil in mice.
Topics: Administration, Oral; Analgesics; Animals; Antioxidants; Citrus; Disease Models, Animal; Free Radical Scavengers; Male; Mice; Naloxone; Oils, Volatile; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Rutaceae | 2011 |
Identification of active compounds from Aurantii Immatri Pericarpium attenuating brain injury in a rat model of ischemia-reperfusion.
Topics: Animals; Apoptosis; Brain Ischemia; Citrus; Disease Models, Animal; DNA Fragmentation; Flavones; Fruit; Hep G2 Cells; Humans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2013 |
Suppression of infection-induced endotoxin shock in mice by a citrus flavanone naringin.
Topics: Animals; Anti-Infective Agents; Citrus; Disease Models, Animal; Endotoxins; Female; Male; Mice; Mice, Inbred BALB C; Phytotherapy; Salmonella Food Poisoning; Salmonella typhimurium; Shock, Septic | 2004 |
Further studies on the anticancer activity of citrus limonoids.
Topics: Animals; Antineoplastic Agents; Benzoxepins; Citrus; Cricetinae; Disease Models, Animal; Female; Fruit; Limonins; Mesocricetus; Mouth Neoplasms; Structure-Activity Relationship | 2004 |
Effects of the essential oil from Citrus aurantium L. in experimental anxiety models in mice.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Citrus; Disease Models, Animal; Fruit; Male; Mice; Motor Activity; Obsessive-Compulsive Disorder; Oils, Volatile; Plant Oils | 2006 |
Experimental phytophotodermatitis.
Topics: Animals; Citrus; Dermatitis, Phototoxic; Disease Models, Animal; Epithelium; Fruit; Rats; Time Factors; Vacuoles | 2005 |
Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni.
Topics: Animals; Biomarkers; Citrus; Commiphora; Disease Models, Animal; Drug Evaluation, Preclinical; Liver; Male; Mice; Phytotherapy; Plant Extracts; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides; Terpenes | 2005 |
Effect of chronic administration of fruit extract (Citrus unshiu Marc.) on glucose tolerance in GK rats, a model of type 2 diabetes.
Topics: Animals; Blood Glucose; Body Weight; Citrus; Diabetes Mellitus, Type 2; Disease Models, Animal; Fruit; Glucose Tolerance Test; Male; Plant Extracts; Rats | 2006 |
Anti-inflammatory effect of lemon mucilage: in vivo and in vitro studies.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Citrus; Disease Models, Animal; Edema; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Rats; Rats, Wistar; Superoxides; Time Factors | 2005 |
Tissue lipid lowering-effect of a traditional Nigerian anti-diabetic infusion of Rauwolfia vomitoria foilage and Citrus aurantium fruit.
Topics: Animals; Blood Glucose; Body Weight; Citrus; Diabetes Mellitus, Type 2; Disease Models, Animal; Eating; Fruit; Hypoglycemic Agents; Lipid Metabolism; Mice; Mice, Inbred C57BL; Nigeria; Phytotherapy; Plant Extracts; Plant Leaves; Rauwolfia; Triglycerides | 2006 |
Citrus juice modulates bone strength in male senescent rat model of osteoporosis.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Antioxidants; Beverages; Bone and Bones; Bone Density; Citrus; Disease Models, Animal; Hydroxyproline; Male; Orchiectomy; Osteoporosis; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
Topics: Adipocytes; Administration, Oral; Animals; Blood Glucose; Cholesterol; Citrus; Cricetinae; Cytokines; Disease Models, Animal; Flavones; Fructose; Glucose Tolerance Test; Homeostasis; Hypercholesterolemia; Hypolipidemic Agents; Insulin Resistance; Lipids; Liver; Male; Mesocricetus; Plant Extracts; PPAR gamma; Triglycerides | 2006 |
Suppression of collagen-induced arthritis by oral administration of the citrus flavonoid hesperidin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Citrus; Collagen; Disease Models, Animal; Down-Regulation; Hesperidin; Knee Joint; Macrophages; Mice; Phytotherapy; Plant Extracts; RNA, Messenger; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha | 2006 |
Lemon juice has protective activity in a rat urolithiasis model.
Topics: Animals; Beverages; Calcium Oxalate; Citrus; Disease Models, Animal; Male; Nephrolithiasis; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2007 |
Anti-allergic effect of a combination of Citrus unshiu unripe fruits extract and prednisolone on picryl chloride-induced contact dermatitis in mice.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Citrus; Dermatitis, Contact; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Edema; Erythema; Female; Fruit; Glucocorticoids; Hesperidin; Injections, Subcutaneous; Mice; Mice, Inbred ICR; Phytotherapy; Picryl Chloride; Plant Extracts; Prednisolone | 2008 |
Preliminary study of fresh juice of Benincasa hispida on morphine addiction in mice.
Topics: Animals; Behavior, Animal; Beverages; Citrus; Diarrhea; Disease Models, Animal; Female; Male; Mice; Morphine; Morphine Dependence; Narcotic Antagonists; Plant Extracts; Substance Withdrawal Syndrome | 2000 |
Polyphenol antioxidants in citrus juices: in vitro and in vivo studies relevant to heart disease.
Topics: Adult; Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Beverages; Citrus; Cricetinae; Diet, Atherogenic; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Female; Flavonoids; Heart Diseases; Hesperidin; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipids; Male; Mesocricetus; Middle Aged; Oxidation-Reduction; Phenols; Plant Extracts; Polymers; Species Specificity | 2002 |
Grapefruit pectin inhibits hypercholesterolemia and atherosclerosis in miniature swine.
Topics: Animals; Cholesterol; Citrus; Coronary Artery Disease; Diet, Atherogenic; Dietary Fiber; Disease Models, Animal; Female; Hypercholesterolemia; Pectins; Random Allocation; Swine; Swine, Miniature; Triglycerides | 1988 |